Dissecting the Catalytic Mechanism of Trypanosoma brucei Trypanothione Synthetase by Kinetic Analysis and Computational Modeling

por Leroux, Alejandro E., Haanstra, Jurgen R., Bakker, Barbara M., Krauth-Siegel, R. Luise
Publicado 2013

Low affinity uniporter carrier proteins can increase net substrate uptake rate by reducing efflux

por Bosdriesz, Evert, Wortel, Meike T., Haanstra, Jurgen R., Wagner, Marijke J., de la Torre Cortés, Pilar, Teusink, Bas
Publicado 2018

Quantitative analysis of amino acid metabolism in liver cancer links glutamate excretion to nucleotide synthesis

por Nilsson, Avlant, Haanstra, Jurgen R., Engqvist, Martin, Gerding, Albert, Bakker, Barbara M., Klingmüller, Ursula, Teusink, Bas, Nielsen, Jens
Publicado 2020

Loss of Ercc1 Results in a Time- and Dose-Dependent Reduction of Proliferating Early Hematopoietic Progenitors

por Verhagen-Oldenampsen, Judith H. E., Haanstra, Jurgen R., van Strien, Paulina M. H., Valkhof, Marijke, Touw, Ivo P., von Lindern, Marieke
Publicado 2012

Transcriptome-wide analysis of trypanosome mRNA decay reveals complex degradation kinetics and suggests a role for co-transcriptional degradation in determining mRNA levels

por Fadda, Abeer, Ryten, Mark, Droll, Dorothea, Rojas, Federico, Färber, Valentin, Haanstra, Jurgen R, Merce, Clemetine, Bakker, Barbara M, Matthews, Keith, Clayton, Christine
Publicado 2014

Integrative analysis of the Trypanosoma brucei gene expression cascade predicts differential regulation of mRNA processing and unusual control of ribosomal protein expression

por Antwi, Enoch B., Haanstra, Jurgen R., Ramasamy, Gowthaman, Jensen, Bryan, Droll, Dorothea, Rojas, Federico, Minia, Igor, Terrao, Monica, Mercé, Clémentine, Matthews, Keith, Myler, Peter J., Parsons, Marilyn, Clayton, Christine
Publicado 2016

Naphthoquinone Derivatives Exert Their Antitrypanosomal Activity via a Multi-Target Mechanism

por Pieretti, Simone, Haanstra, Jurgen R., Mazet, Muriel, Perozzo, Remo, Bergamini, Christian, Prati, Federica, Fato, Romana, Lenaz, Giorgio, Capranico, Giovanni, Brun, Reto, Bakker, Barbara M., Michels, Paul A. M., Scapozza, Leonardo, Bolognesi, Maria Laura, Cavalli, Andrea
Publicado 2013

Targeting pathogen metabolism without collateral damage to the host

por Haanstra, Jurgen R., Gerding, Albert, Dolga, Amalia M., Sorgdrager, Freek J. H., Buist-Homan, Manon, du Toit, François, Faber, Klaas Nico, Holzhütter, Hermann-Georg, Szöör, Balázs, Matthews, Keith R., Snoep, Jacky L., Westerhoff, Hans V., Bakker, Barbara M.
Publicado 2017

How much (ATP) does it cost to build a trypanosome? A theoretical study on the quantity of ATP needed to maintain and duplicate a bloodstream-form Trypanosoma brucei cell

por Nascimento, Janaina F., Souza, Rodolpho O. O., Alencar, Mayke B., Marsiccobetre, Sabrina, Murillo, Ana M., Damasceno, Flávia S., Girard, Richard B. M. M., Marchese, Letícia, Luévano-Martinez, Luis A., Achjian, Renan W., Haanstra, Jurgen R., Michels, Paul A. M., Silber, Ariel M.
Publicado 2023

Correction: How much (ATP) does it cost to build a trypanosome? A theoretical study on the quantity of ATP needed to maintain and duplicate a bloodstream-form Trypanosoma brucei ce...

por Nascimento, Janaina F., O. Souza, Rodolpho O., Alencar, Mayke B., Marsiccobetre, Sabrina, Murillo, Ana M., Damasceno, Flávia S., M. Girard, Richard B. M., Marchese, Letícia, Luévano-Martinez, Luis A., Achjian, Renan W., Haanstra, Jurgen R., M. Michels, Paul A., Silber, Ariel M.
Publicado 2023