Patient-derived skin fibroblasts as a model to study frontotemporal lobar degeneration

por Hoffmann, Dorit, Haapasalo, Annakaisa
Publicado 2022

Synaptic dysfunction and septin protein family members in neurodegenerative diseases

por Marttinen, Mikael, Kurkinen, Kaisa MA, Soininen, Hilkka, Haapasalo, Annakaisa, Hiltunen, Mikko
Publicado 2015

Prodromal and Early bvFTD: Evaluating Clinical Features and Current Biomarkers

por Katisko, Kasper, Cajanus, Antti, Korhonen, Titta, Remes, Anne M., Haapasalo, Annakaisa, Solje, Eino
Publicado 2019

State-of-the-Art Methods and Emerging Fluid Biomarkers in the Diagnostics of Dementia—A Short Review and Diagnostic Algorithm

por Solje, Eino, Benussi, Alberto, Buratti, Emanuele, Remes, Anne M., Haapasalo, Annakaisa, Borroni, Barbara
Publicado 2021

γ-Secretase Components as Predictors of Breast Cancer Outcome

por Peltonen, Hanna M., Haapasalo, Annakaisa, Hiltunen, Mikko, Kataja, Vesa, Kosma, Veli-Matti, Mannermaa, Arto
Publicado 2013

Bepridil decreases Aβ and calcium levels in the thalamus after middle cerebral artery occlusion in rats

por Sarajärvi, Timo, Lipsanen, Anu, Mäkinen, Petra, Peräniemi, Sirpa, Soininen, Hilkka, Haapasalo, Annakaisa, Jolkkonen, Jukka, Hiltunen, Mikko
Publicado 2012

C9orf72 Proteins Regulate Autophagy and Undergo Autophagosomal or Proteasomal Degradation in a Cell Type-Dependent Manner

por Leskelä, Stina, Huber, Nadine, Rostalski, Hannah, Natunen, Teemu, Remes, Anne M., Takalo, Mari, Hiltunen, Mikko, Haapasalo, Annakaisa
Publicado 2019

Deficient neurotransmitter systems and synaptic function in frontotemporal lobar degeneration—Insights into disease mechanisms and current therapeutic approaches

por Huber, Nadine, Korhonen, Sonja, Hoffmann, Dorit, Leskelä, Stina, Rostalski, Hannah, Remes, Anne M., Honkakoski, Paavo, Solje, Eino, Haapasalo, Annakaisa
Publicado 2021

Brainstem atrophy is linked to extrapyramidal symptoms in frontotemporal dementia

por Heikkinen, Sami, Cajanus, Antti, Katisko, Kasper, Hartikainen, Päivi, Vanninen, Ritva, Haapasalo, Annakaisa, Krüger, Johanna, Remes, Anne M., Solje, Eino
Publicado 2022

Regulation of key proteins in Alzheimer’s disease molecular pathogenesis by ubiquilin-1

por Takalo, Mari, Viswanathan, Jayashree, Natunen, Teemu, Kurkinen, Kaisa MA, Tanila, Heikki, Soininen, Hilkka, Tanzi, Rudolph E, Hiltunen, Mikko, Haapasalo, Annakaisa
Publicado 2013

Molecular Mechanisms of Synaptotoxicity and Neuroinflammation in Alzheimer’s Disease

por Marttinen, Mikael, Takalo, Mari, Natunen, Teemu, Wittrahm, Rebekka, Gabbouj, Sami, Kemppainen, Susanna, Leinonen, Ville, Tanila, Heikki, Haapasalo, Annakaisa, Hiltunen, Mikko
Publicado 2018

Rare PMP22 variants in mild to severe neuropathy uncorrelated to plasma GDF15 or neurofilament light

por Palu, Edouard, Järvilehto, Julius, Pennonen, Jana, Huber, Nadine, Herukka, Sanna-Kaisa, Haapasalo, Annakaisa, Isohanni, Pirjo, Tyynismaa, Henna, Auranen, Mari, Ylikallio, Emil
Publicado 2023

Altered Insulin Signaling in Alzheimer’s Disease Brain – Special Emphasis on PI3K-Akt Pathway

por Gabbouj, Sami, Ryhänen, Simo, Marttinen, Mikael, Wittrahm, Rebekka, Takalo, Mari, Kemppainen, Susanna, Martiskainen, Henna, Tanila, Heikki, Haapasalo, Annakaisa, Hiltunen, Mikko, Natunen, Teemu
Publicado 2019

Astrocytes and Microglia as Potential Contributors to the Pathogenesis of C9orf72 Repeat Expansion-Associated FTLD and ALS

por Rostalski, Hannah, Leskelä, Stina, Huber, Nadine, Katisko, Kasper, Cajanus, Antti, Solje, Eino, Marttinen, Mikael, Natunen, Teemu, Remes, Anne M., Hiltunen, Mikko, Haapasalo, Annakaisa
Publicado 2019

Serum neurofilament light chain in FTLD: association with C9orf72, clinical phenotype, and prognosis

por Cajanus, Antti, Katisko, Kasper, Kontkanen, Aleksi, Jääskeläinen, Olli, Hartikainen, Päivi, Haapasalo, Annakaisa, Herukka, Sanna‐Kaisa, Vanninen, Ritva, Solje, Eino, Hall, Anette, Remes, Anne M.
Publicado 2020

FTLD Patient–Derived Fibroblasts Show Defective Mitochondrial Function and Accumulation of p62

por Leskelä, Stina, Hoffmann, Dorit, Rostalski, Hannah, Huber, Nadine, Wittrahm, Rebekka, Hartikainen, Päivi, Korhonen, Ville, Leinonen, Ville, Hiltunen, Mikko, Solje, Eino, Remes, Anne M., Haapasalo, Annakaisa
Publicado 2021

Modifiable potential risk factors in familial and sporadic frontotemporal dementia

por Soppela, Helmi, Katisko, Kasper, Gadola, Yasmine, Krüger, Johanna, Hartikainen, Päivi, Alberici, Antonella, Benussi, Alberto, Koivisto, Anne, Haapasalo, Annakaisa, Remes, Anne M, Borroni, Barbara, Solje, Eino
Publicado 2022

MECP2 Increases the Pro-Inflammatory Response of Microglial Cells and Phosphorylation at Serine 423 Regulates Neuronal Gene Expression upon Neuroinflammation

por Wittrahm, Rebekka, Takalo, Mari, Marttinen, Mikael, Kuulasmaa, Teemu, Mäkinen, Petra, Kemppainen, Susanna, Martiskainen, Henna, Rauramaa, Tuomas, Pike, Ian, Leinonen, Ville, Natunen, Teemu, Haapasalo, Annakaisa, Hiltunen, Mikko
Publicado 2021

Increased γ-Secretase Activity in Idiopathic Normal Pressure Hydrocephalus Patients with β-Amyloid Pathology

por Laiterä, Tiina, Sarajärvi, Timo, Haapasalo, Annakaisa, Puli, Lakshman, Kauppinen, Tarja, Mäkinen, Petra, Rauramaa, Tuomas, Tanila, Heikki, Jääskeläinen, Juha E., Alafuzoff, Irina, Soininen, Hilkka, Leinonen, Ville, Hiltunen, Mikko
Publicado 2014

Decreased plasma C‐reactive protein levels in APOE ε4 allele carriers

por Martiskainen, Henna, Takalo, Mari, Solomon, Alina, Stančáková, Alena, Marttinen, Mikael, Natunen, Teemu, Haapasalo, Annakaisa, Herukka, Sanna‐Kaisa, Kuusisto, Johanna, Soininen, Hilkka, Kivipelto, Miia, Laakso, Markku, Hiltunen, Mikko
Publicado 2018