HGG-53. PROJECT HOPE: “PEDIATRIC AND AYA HIGH-GRADE GLIOMA OMICS PROJECT”- A LONGITUDINAL MOLECULAR LANDSCAPE OF HIGH-GRADE GLIOMAS RESOLVED AT SINGLE-CELL LEVEL

por Hack, Olivia A, Babikir, Husam, Jiang, Li, Shamardani, Karin, Liu, Ilon, Shaw, McKenzie, Cunliffe-Koehler, Kennedy, Resnick, Adam, Prados, Michael, Monje, Michelle, Diaz, Aaron, Filbin, Mariella G
Publicado 2020

EPEN-12. COMPARING CELLULAR HIERARCHIES AND SPATIAL ARCHITECTURE ACROSS MOLECULAR SUBGROUPS OF SUPRATENTORIAL EPENDYMOMAS

por Jeong, Daeun, Maass, Kendra K, Ghasemi, David R, Englinger, Bernhard, Jiang, Li, Nascimento, Andrezza, Hack, Olivia A, Shaw, McKenzie L, Pfister, Stefan M, Kool, Marcel, Gojo, Johannes, Pajtler *, Kristian W, Filbin *, Mariella G
Publicado 2023

ETMR-17. SINGLE-CELL TRANSCRIPTOME ANALYSIS OF ETMR PATIENT SAMPLES

por Hovestadt, Volker, Shaw, McKenzie L, Beck, Alexander, Lambo, Sander, Hack, Olivia A, Gojo, Johannes, Madlener, Sibylle, Mayr, Lisa, Haberler, Christine, Czech, Thomas, Hanson, Derek R, Koschmann, Carl, Jabado, Nada, Huang, Annie A, Slavc, Irene, Pfister, Stefan M, Alexandrescu, Sanda, Bernstein, Bradley E, Kool, Marcel, Filbin, Mariella G
Publicado 2020

ATRT-10. SINGLE-CELL TRANSCRIPTOME ANALYSIS REVEALS CELLULAR HIERARCHIES AND THERAPEUTIC VULNERABILITIES OF ETMR

por Beck, Alexander, Gabler, Lisa, Cruzeiro, Gustavo A V, Lambo, Sander, Englinger, Bernhard, Shaw, McKenzie L, Hack, Olivia A, Liu, Ilon, Junior, Carlos A O de Biagi, Haase, Rebecca D, Klenner, Marbod, Freidel, Pia, Madlener, Sibylle, Mayr, Lisa, Senfter, Daniel, Peyrl, Andreas, Slavc, Irene, Lötsch, Daniela, Dorfer, Christian, Haberler, Christine, Pfister, Stefan M, Baird, Lissa, Chi, Susan N, Alexandrescu, Sanda, Gojo, Johannes, Kool, Marcel, Hovestadt, Volker, Filbin, Mariella G
Publicado 2023

HGG-17. SINGLE-CELL AND SPATIAL ANALYSES DECIPHER THE UNIQUE INVASIVE GROWTH PATTERN OF GLIOMATOSIS CEREBRI

por Crampsie, Shauna, Liu, Ilon, Petrilli, Lucia Lisa, Mackay, Alan, Spinozzi, Giulio, Grabovska, Yura, Hack, Olivia A, Kessler, Ketty, Temelso, Sara, Carvalho, Diana Martins, Burford, Anna, Sejdiu, Drenusha, Molinari, Valeria, Shaw, McKenzie L, Mire, Hafsa M, Pericoli, Giulia, Cerimele, Alfredo, Barry, Clémentine, Cocito, Carolina, Debily, Marie-Anne, Kergrohen, Thomas, Ajlil, Yassine, Beccaria, Kévin, Varlet, Pascale, Tauziède-Espariat, Arnault, Mastronuzzi, Angela, Carai, Andrea, Giovannoni, Isabella, Rossi, Sabrina, Miele, Evelina, Grill, Jacques, Jacques, Thomas S, Greenfield, Jeffery P, Castel, David, Vinci, Maria, Filbin, Mariella G, Jones, Chris
Publicado 2023

EPEN-21. IMPAIRED NEURONAL-GLIAL FATE SPECIFICATION IN PEDIATRIC EPENDYMOMA REVEALED BY SINGLE-CELL RNA-SEQ

por Englinger, Bernhard, Gojo, Johannes, Jiang, Li, Hübner, Jens M, Shaw, McKenzie L, Hack, Olivia A, Madlener, Sibylle, Kirchhofer, Dominik, Liu, Ilon, Pyrdol, Jason, Hovestadt, Volker, Mazzola, Emanuele, Mathewson, Nathan D, Trissal, Maria, Lötsch, Daniela, Berger, Walter, Dorfer, Christian, Haberler, Christine, Halfmann, Angela, Mayr, Lisa, Peyrl, Andreas, Geyeregger, Rene, Pajtler, Kristian W, Milde, Till, Geduldig, Jack E, Pelton, Kristine, Czech, Thomas, Ashenberg, Orr, Wucherpfennig, Kai W, Rozenblatt-Rosen, Orit, Alexandrescu, Sanda, Ligon, Keith L, Pfister, Stefan M, Regev, Aviv, Slavc, Irene, Suva, Mario L, Kool, Marcel, Filbin, Mariella
Publicado 2020

DIPG-08. THE LANDSCAPE OF TUMOR CELL STATES AND SPATIAL ORGANIZATION IN H3-K27M MUTANT DIFFUSE MIDLINE GLIOMA ACROSS AGE AND LOCATION

por Liu, Ilon, Jiang, Li, Samuelsson, Erik, Salas, Sergio Marco, Beck, Alexander, Hack, Olivia, Jeong, Daeun, Shaw, McKenzie, Englinger, Bernhard, LaBelle, Jenna, Mire, Hafsa, Madlener, Sibylle, Mayr, Lisa, Quezada, Michael, Trissal, Maria, Panditharatna, Eshini, Ernst, Kati, Vogelzang, Jayne, Gatesman, Taylor, Halbert, Matthew, Palova, Hana, Vesela, Petra, Sterba, Jaroslav, Slaby, Ondrej, Geyeregger, Rene, Diaz, Aaron, Findlay, Izac, Dun, Matt, Resnick, Adam, Suva, Mario, Jones, David, Agnihotri, Sameer, Ostlin, Jessica, Koschmann, Carl, Haberler, Christine, Czech, Thomas, Slavc, Irene, Cotter, Jennifer, Ligon, Keith, Alexandrescu, Sanda, Yung, W K Alfred, Arrillaga-Romany, Isabel, Gojo, Johannes, Monje, Michelle, Nilsson, Mats, Filbin, Mariella
Publicado 2023

Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma

por Gojo, Johannes, Englinger, Bernhard, Jiang, Li, Hübner, Jens M., Shaw, McKenzie L., Hack, Olivia A., Madlener, Sibylle, Kirchhofer, Dominik, Liu, Ilon, Pyrdol, Jason, Hovestadt, Volker, Mazzola, Emanuele, Mathewson, Nathan D., Trissal, Maria, Lötsch, Daniela, Dorfer, Christian, Haberler, Christine, Halfmann, Angela, Mayr, Lisa, Peyrl, Andreas, Geyeregger, Rene, Schwalm, Benjamin, Mauermann, Monica, Pajtler, Kristian W., Milde, Till, Shore, Marni E., Geduldig, Jack E., Pelton, Kristine, Czech, Thomas, Ashenberg, Orr, Wucherpfennig, Kai W., Rozenblatt-Rosen, Orit, Alexandrescu, Sanda, Ligon, Keith L., Pfister, Stefan M., Regev, Aviv, Slavc, Irene, Berger, Walter, Suvà, Mario L., Kool, Marcel, Filbin, Mariella G.
Publicado 2020

HGG-05. PERTURBING GABAERGIC NEURONAL LINEAGE IN DIFFUSE HEMISPHERIC GLIOMA, H3G34-MUTANT, HIGHLIGHTS CDK6 AS A CLINICALLY ACTIONABLE TARGET

por Liu, Ilon, Cruzeiro, Gustavo Alencastro Veiga, Bjerke, Lynn, Rogers, Rebecca, Grabovska, Yura, Beck, Alexander, Mackay, Alan, Barron, Tara, Hack, Olivia, Quezada, Michael, Molinari, Valeria, Shaw, McKenzie, Temelso, Sara, Raynaud, Florence, Ruddle, Ruth, Panditharatna, Eshini, Englinger, Bernhard, Mire, Hafsa, Jiang, Li, Silva, Andrezza Do Nascimento, LaBelle, Jenna, Haase, Rebecca, Rozowsky, Jacob, Nguyen, Quang-De, Pericoli, Giulia, Madlener, Sibylle, Mayr, Lisa, Dorfer, Christian, Geyeregger, Rene, Ricken, Gerda, Ligon, Keith, Alexandrescu, Sanda, Agnihotri, Sameer, Eisenstat, David, Carceller, Fernando, Stapleton, Simon, Bleil, Cristina, Mastronuzzi, Angela, Cole, Kristina, Waanders, Angela, Carcaboso, Angel Montero, Schüller, Ulrich, Vinci, Maria, Hargrave, Darren, Haberler, Christine, Slavc, Irene, Gojo, Johannes, Monje, Michelle, Jones, Chris, Filbin, Mariella
Publicado 2023

DIPG-19. BAF COMPLEX PERTURBATION AS A NOVEL THERAPEUTIC OPPORTUNITY IN H3K27M PEDIATRIC GLIOMA

por Panditharatna, Eshini, Marques, Joana G, Wang, Tingjian, Trissal, Maria, Liu, Ilon, Jiang, Li, Beck, Alexander, Groves, Andrew, Dharia, Neekesh, Hoffman, Samantha, Kugener, Guillaume, Shaw, McKenzie, Hack, Olivia, Dempster, Joshua, Lareau, Caleb, Quezada, Michael, Stanton, Ann-Catherine, Wyatt, Meghan, Kalani, Zohra, Goodale, Amy, Vazquez, Francisca, Piccioni, Federica, Doench, John, Root, David, Anastas, Jamie, Jones, Kristen, Conway, Amy, Stopka, Sylwia, Regan, Michael, Liang, Yu, Seo, Hyuk-Soo, Song, Kijun, Bashyal, Puspalata, Mathewson, Nathan, Dhe-Paganon, Sirano, Suvà, Mario L, Carcaboso, Angel M, Lavarino, Cinzia, Mora, Jaume, Nguyen, Quang-De, Ligon, Keith L, Shi, Yang, Agnihotri, Sameer, Agar, Nathalie Y R, Stegmaier, Kimberly, Stiles, Charles D, Monje, Michelle, Golub, Todd R, Qi, Jun, Filbin, Mariella G
Publicado 2023

HGG-06. EARLY GABAERGIC NEURONAL LINEAGE DEFINES DEPENDENCIES IN HISTONE H3 G34R/V GLIOMA

por Liu, Ilon, Bjerke, Lynn, Cruzeiro, Gustavo Alencastro Veiga, Rogers, Rebecca F, Grabovska, Yura, Panditharatna, Eshini, Mackay, Alan, Barron, Tara, Shaw, McKenzie, Hoffman, Samantha E, Hack, Olivia A, Quezada, Michael A, Dempster, Joshua, Temelso, Sara, Englinger, Bernhard, Molinari, Valeria, Mire, Hafsa M, Jiang, Li, Madlener, Sibylle, Mayr, Lisa, Dorfer, Christian, Geyeregger, Rene, Rota, Christopher, Ricken, Gerda, Alexandrescu, Sanda, Braun, Emelie, Danan-Gotthold, Miri, Hu, Lijuan, Siletti, Kimberly, Sundstroem, Erik, Hodge, Rebecca, Lein, Ed, Agnihotri, Sameer, Eisenstat, David D, Carceller, Fernando, Stapleton, Simon, Bleil, Cristina, Mastronuzzi, Angela, Cole, Kristina A, Waanders, Angela J, Carcaboso, Angel Montero, Vinci, Maria, Hargrave, Darren, Haberler, Christine, Gojo, Johannes, Slavc, Irene, Linnarsson, Sten, Monje, Michelle, Jones, Chris, Filbin, Mariella G
Publicado 2021

The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location

por Liu, Ilon, Jiang, Li, Samuelsson, Erik R., Marco Salas, Sergio, Beck, Alexander, Hack, Olivia A., Jeong, Daeun, Shaw, McKenzie L., Englinger, Bernhard, LaBelle, Jenna, Mire, Hafsa M., Madlener, Sibylle, Mayr, Lisa, Quezada, Michael A., Trissal, Maria, Panditharatna, Eshini, Ernst, Kati J., Vogelzang, Jayne, Gatesman, Taylor A., Halbert, Matthew E., Palova, Hana, Pokorna, Petra, Sterba, Jaroslav, Slaby, Ondrej, Geyeregger, Rene, Diaz, Aaron, Findlay, Izac J., Dun, Matthew D., Resnick, Adam, Suvà, Mario L., Jones, David T. W., Agnihotri, Sameer, Svedlund, Jessica, Koschmann, Carl, Haberler, Christine, Czech, Thomas, Slavc, Irene, Cotter, Jennifer A., Ligon, Keith L., Alexandrescu, Sanda, Yung, W. K. Alfred, Arrillaga-Romany, Isabel, Gojo, Johannes, Monje, Michelle, Nilsson, Mats, Filbin, Mariella G.
Publicado 2022

HGG-19. CLINICAL RESPONSE TO THE PDGFRA/KIT INHIBITOR AVAPRITINIB IN PEDIATRIC AND YOUNG ADULT HIGH-GRADE GLIOMA PATIENTS WITH H3K27M OR PDGFRA GENOMIC ALTERATIONS

por Trissal, Maria, Mayr, Lisa, Schwark, Kallen, LaBelle, Jenna, Kong, Seongbae, Furtner, Julia, Weiler-Wichtl, Liesa, Supko, Jeffrey, Rozowsky, Jacob, Hack, Olivia, Groves, Andrew, Marques, Joana, Leiss, Ulrike, Rosenmayr, Verena, Dubois, Frank, Greenwald, Noah F, Madlener, Sibylle, Guntner, Armin Sebastian, Pálová, Hana, Stepien, Natalia, Lötsch-Gojo, Daniela, Dorfer, Christian, Dieckmann, Karen, Peyrl, Andreas, Azizi, Amadeo A, Baumgartner, Alicia, Slabý, Ondřej, Pokorná, Petra, Bandopadhayay, Pratiti, Rameen_Beroukhim@dfci.harvard.edu Beroukhim, Rameen Beroukhim, Ligon, Keith L, Kramm, Christof M, Bronsema, Annika, Bailey, Simon, Stucklin, Ana Guerreiro, Mueller, Sabine Mueller, Jones, David T W, Jäger, Natalie, Mullauer, Leonhard, Haberler, Christine, Kumar-Sinha, Chandan, Chinnaiyan, Arul, Mody, Rajen, Sterba.Jaroslav@fnbrno.cz Štěrba, Jaroslav Štěrba, Skrypek, Mary, Martinez, Nina, Bowers, Daniel C, Koschmann, Carl Koschmann, Gojo, Johannes, Filbin, Mariella
Publicado 2023

BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma

por Panditharatna, Eshini, Marques, Joana G., Wang, Tingjian, Trissal, Maria C., Liu, Ilon, Jiang, Li, Beck, Alexander, Groves, Andrew, Dharia, Neekesh V., Li, Deyao, Hoffman, Samantha E., Kugener, Guillaume, Shaw, McKenzie L., Mire, Hafsa M., Hack, Olivia A., Dempster, Joshua M., Lareau, Caleb, Dai, Lingling, Sigua, Logan H., Quezada, Michael A., Stanton, Ann-Catherine J., Wyatt, Meghan, Kalani, Zohra, Goodale, Amy, Vazquez, Francisca, Piccioni, Federica, Doench, John G., Root, David E., Anastas, Jamie N., Jones, Kristen L., Conway, Amy Saur, Stopka, Sylwia, Regan, Michael S., Liang, Yu, Seo, Hyuk-Soo, Song, Kijun, Bashyal, Puspalata, Jerome, William P., Mathewson, Nathan D., Dhe-Paganon, Sirano, Suvà, Mario L., Carcaboso, Angel M., Lavarino, Cinzia, Mora, Jaume, Nguyen, Quang-De, Ligon, Keith L., Shi, Yang, Agnihotri, Sameer, Agar, Nathalie Y.R., Stegmaier, Kimberly, Stiles, Charles D., Monje, Michelle, Golub, Todd R., Qi, Jun, Filbin, Mariella G.
Publicado 2022