Isotopically Labeled Desthiobiotin Azide (isoDTB) Tags Enable Global Profiling of the Bacterial Cysteinome

por Zanon, Patrick R. A., Lewald, Lisa, Hacker, Stephan M.
Publicado 2020

Light-Activatable, 2,5-Disubstituted Tetrazoles for the Proteome-wide Profiling of Aspartates and Glutamates in Living Bacteria

por Bach, Kathrin, Beerkens, Bert L. H., Zanon, Patrick R. A., Hacker, Stephan M.
Publicado 2020

A tailored phosphoaspartate probe unravels CprR as a response regulator in Pseudomonas aeruginosa interkingdom signaling

por Allihn, Patrick W. A., Hackl, Mathias W., Ludwig, Christina, Hacker, Stephan M., Sieber, Stephan A.
Publicado 2021

A chemical probe unravels the reactive proteome of health-associated catechols

por Weigert Muñoz, Angela, Meighen-Berger, Kevin M., Hacker, Stephan M., Feige, Matthias J., Sieber, Stephan A.
Publicado 2023

HSP-90/kinase complexes are stabilized by the large PPIase FKB-6

por Sima, Siyuan, Barkovits, Katalin, Marcus, Katrin, Schmauder, Lukas, Hacker, Stephan M., Hellwig, Nils, Morgner, Nina, Richter, Klaus
Publicado 2021

Eukaryotic catecholamine hormones influence the chemotactic control of Vibrio campbellii by binding to the coupling protein CheW

por Weigert Muñoz, Angela, Hoyer, Elisabeth, Schumacher, Kilian, Grognot, Marianne, Taute, Katja M., Hacker, Stephan M., Sieber, Stephan A., Jung, Kirsten
Publicado 2022

Broad Spectrum Antibiotic Xanthocillin X Effectively Kills Acinetobacter baumanniivia Dysregulation of Heme Biosynthesis

por Hübner, Ines, Shapiro, Justin A., Hoßmann, Jörn, Drechsel, Jonas, Hacker, Stephan M., Rather, Philip N., Pieper, Dietmar H., Wuest, William M., Sieber, Stephan A.
Publicado 2021

Neocarzilin A Is a Potent Inhibitor of Cancer Cell Motility Targeting VAT-1 Controlled Pathways

por Gleissner, Carolin M.-L., Pyka, Carolin L., Heydenreuter, Wolfgang, Gronauer, Thomas F., Atzberger, Carina, Korotkov, Vadim S., Cheng, Weiting, Hacker, Stephan M., Vollmar, Angelika M., Braig, Simone, Sieber, Stephan A.
Publicado 2019

The covalent reactivity of functionalized 5-hydroxy-butyrolactams is the basis for targeting of fatty acid binding protein 5 (FABP5) by the neurotrophic agent MT-21

por Svenningsen, Esben B., Ottosen, Rasmus N., Jørgensen, Katrine H., Nisavic, Marija, Larsen, Camilla K., Hansen, Bente K., Wang, Yong, Lindorff-Larsen, Kresten, Tørring, Thomas, Hacker, Stephan M., Palmfeldt, Johan, Poulsen, Thomas B.
Publicado 2022

Repurposing human kinase inhibitors to create an antibiotic active against drug-resistant Staphylococcus aureus, persisters and biofilms

por Le, Philipp, Kunold, Elena, Macsics, Robert, Rox, Katharina, Jennings, Megan C., Ugur, Ilke, Reinecke, Maria, Chaves-Moreno, Diego, Hackl, Mathias W., Fetzer, Christian, Mandl, Franziska A. M., Lehmann, Johannes, Korotkov, Vadim S., Hacker, Stephan M., Kuster, Bernhard, Antes, Iris, Pieper, Dietmar H., Rohde, Manfred, Wuest, William M., Medina, Eva, Sieber, Stephan A.
Publicado 2019

SDR enzymes oxidize specific lipidic alkynylcarbinols into cytotoxic protein-reactive species

por Demange, Pascal, Joly, Etienne, Marcoux, Julien, Zanon, Patrick RA, Listunov, Dymytrii, Rullière, Pauline, Barthes, Cécile, Noirot, Céline, Izquierdo, Jean-Baptiste, Rozié, Alexandrine, Pradines, Karen, Hee, Romain, de Brito, Maria Vieira, Marcellin, Marlène, Serre, Remy-Felix, Bouchez, Olivier, Burlet-Schiltz, Odile, Oliveira, Maria Conceição Ferreira, Ballereau, Stéphanie, Bernardes-Génisson, Vania, Maraval, Valérie, Calsou, Patrick, Hacker, Stephan M, Génisson, Yves, Chauvin, Remi, Britton, Sébastien
Publicado 2022