Progressive right ventricular functional and structural changes in a mouse model of pulmonary arterial hypertension

por Wang, Zhijie, Schreier, David A., Hacker, Timothy A., Chesler, Naomi C.
Publicado 2013

Limiting collagen turnover via collagenase‐resistance attenuates right ventricular dysfunction and fibrosis in pulmonary arterial hypertension

por Golob, Mark J., Wang, Zhijie, Prostrollo, Anthony J., Hacker, Timothy A., Chesler, Naomi C.
Publicado 2016

Significant reduction of ischemia‐reperfusion cell death in mouse myocardial infarcts using the immediate‐acting PrC‐210 ROS‐scavenger

por Hacker, Timothy A., Diarra, Gaoussou, Fahl, Bryan L., Back, Susan, Kaufmann, Erin, Fahl, William E.
Publicado 2019

Cardiac MyBP-C phosphorylation regulates the Frank–Starling relationship in murine hearts

por Hanft, Laurin M., Fitzsimons, Daniel P., Hacker, Timothy A., Moss, Richard L., McDonald, Kerry S.
Publicado 2021

Two-site regional oxygen saturation and capnography monitoring during resuscitation after cardiac arrest in a swine pediatric ventricular fibrillatory arrest model

por Al-Subu, Awni M., Hacker, Timothy A., Eickhoff, Jens C., Ofori-Amanfo, George, Eldridge, Marlowe W.
Publicado 2019

Does prenatal alcohol exposure cause a metabolic syndrome? (Non-)evidence from a mouse model of fetal alcohol spectrum disorder

por Amos-Kroohs, Robyn M., Nelson, David W., Hacker, Timothy A., Yen, Chi-Liang Eric, Smith, Susan M.
Publicado 2018

Effects of calorie restriction on the lifespan and healthspan of POLG mitochondrial mutator mice

por Someya, Shinichi, Kujoth, Gregory C., Kim, Mi-Jung, Hacker, Timothy A., Vermulst, Marc, Weindruch, Richard, Prolla, Tomas A.
Publicado 2017

A Large Animal Model of Right Ventricular Failure due to Chronic Thromboembolic Pulmonary Hypertension: A Focus on Function

por Mulchrone, Ashley, Kellihan, Heidi B., Forouzan, Omid, Hacker, Timothy A., Bates, Melissa L., Francois, Christopher J., Chesler, Naomi C.
Publicado 2019

Development of Aortic Valve Disease in Familial Hypercholesterolemic Swine: Implications for Elucidating Disease Etiology

por Porras, Ana M., Shanmuganayagam, Dhanansayan, Meudt, Jennifer J., Krueger, Christian G., Hacker, Timothy A., Rahko, Peter S., Reed, Jess D., Masters, Kristyn S.
Publicado 2015

Single-dose mRNA therapy via biomaterial-mediated sequestration of overexpressed proteins

por Khalil, Andrew S., Yu, Xiaohua, Umhoefer, Jennifer M., Chamberlain, Connie S., Wildenauer, Linzie A., Diarra, Gaoussou M., Hacker, Timothy A., Murphy, William L.
Publicado 2020

Estrogen maintains mitochondrial content and function in the right ventricle of rats with pulmonary hypertension

por Liu, Aiping, Philip, Jennifer, Vinnakota, Kalyan C., Van den Bergh, Francoise, Tabima, Diana M., Hacker, Timothy, Beard, Daniel A., Chesler, Naomi C.
Publicado 2017

Transgenic overexpression of the SUR2A-55 splice variant in mouse heart reduces infract size and promotes protective mitochondrial function

por Ramratnam, Mohun, Kenny, Barrett, Kyle, John W., Wiedmeyer, Brandi, Hacker, Timothy A., Barefield, David Y., McNally, Elizabeth M., Makielski, Jonathan C.
Publicado 2018

Murine cardiac fibrosis localization using adaptive Bayesian cardiac strain imaging in vivo

por Al Mukaddim, Rashid, Weichmann, Ashley M., Taylor, Rachel, Hacker, Timothy A., Pier, Thomas, Hardin, Joseph, Graham, Melissa, Mitchell, Carol C., Varghese, Tomy
Publicado 2022

Ablation of the Cardiac-Specific Gene Leucine-Rich Repeat Containing 10 (Lrrc10) Results in Dilated Cardiomyopathy

por Brody, Matthew J., Hacker, Timothy A., Patel, Jitandrakumar R., Feng, Li, Sadoshima, Junichi, Tevosian, Sergei G., Balijepalli, Ravi C., Moss, Richard L., Lee, Youngsook
Publicado 2012

Overexpression of a Short Sulfonylurea Splice Variant Increases Cardiac Glucose Uptake and Uncouples Mitochondria by Regulating ROMK Activity

por El-Meanawy, Sarah K., Dooge, Holly, Wexler, Allison C., Kosmach, Anna C., Serban, Lara, Santos, Elizabeth A., Alvarado, Francisco J., Hacker, Timothy A., Ramratnam, Mohun
Publicado 2023

Biodistribution and Clearance of Human Mesenchymal Stem Cells by Quantitative Three-Dimensional Cryo-Imaging After Intravenous Infusion in a Rat Lung Injury Model

por Schmuck, Eric G., Koch, Jill M., Centanni, John M., Hacker, Timothy A., Braun, Rudolf K., Eldridge, Marlowe, Hei, Derek J., Hematti, Peiman, Raval, Amish N.
Publicado 2016

RBM20 phosphorylation and its role in nucleocytoplasmic transport and cardiac pathogenesis

por Zhang, Yanghai, Wang, Chunyan, Sun, Mingming, Jin, Yutong, Braz, Camila Urbano, Khatib, Hasan, Hacker, Timothy A., Liss, Martin, Gotthardt, Michael, Granzier, Henk, Ge, Ying, Guo, Wei
Publicado 2022

Disruption of the nuclear localization signal in RBM20 is causative in dilated cardiomyopathy

por Zhang, Yanghai, Gregorich, Zachery R., Wang, Yujuan, Braz, Camila Urbano, Zhang, Jibin, Liu, Yang, Liu, Peiheng, Shen, Jiaxi, Aori, Nanyumuzi, Hacker, Timothy A., Granzier, Henk, Guo, Wei
Publicado 2023

Altered Right Ventricular Mechanical Properties Are Afterload Dependent in a Rodent Model of Bronchopulmonary Dysplasia

por Patel, Jitandrakumar R., Barton, Gregory P., Braun, Rudolf K., Goss, Kara N., Haraldsdottir, Kristin, Hopp, Alexandria, Diffee, Gary, Hacker, Timothy A., Moss, Richard L., Eldridge, Marlowe W.
Publicado 2017

Stretchable piezoelectric biocrystal thin films

por Li, Jun, Carlos, Corey, Zhou, Hao, Sui, Jiajie, Wang, Yikai, Silva-Pedraza, Zulmari, Yang, Fan, Dong, Yutao, Zhang, Ziyi, Hacker, Timothy A., Liu, Bo, Mao, Yanchao, Wang, Xudong
Publicado 2023