Brief Guide: Experimental Strategies for High-Quality Hit Selection from Small-Molecule Screening Campaigns

por Rothenaigner, Ina, Hadian, Kamyar
Publicado 2021

Vaccination versus SARS-CoV-2 Omicron: three vaccine doses win the battle

por Popowicz, Grzegorz Maria, Pyrc, Krzysztof, Hadian, Kamyar
Publicado 2022

An in vivo high-throughput screening for riboswitch ligands using a reverse reporter gene system

por Kirchner, Marion, Schorpp, Kenji, Hadian, Kamyar, Schneider, Sabine
Publicado 2017

Heterogenous nuclear ribonucleoprotein Q increases protein expression from HIV-1 Rev-dependent transcripts

por Vincendeau, Michelle, Nagel, Daniel, Brenke, Jara K, Brack-Werner, Ruth, Hadian, Kamyar
Publicado 2013

Machine Learning Classifies Ferroptosis and Apoptosis Cell Death Modalities with TfR1 Immunostaining

por Jin, Jenny, Schorpp, Kenji, Samaga, Daniel, Unger, Kristian, Hadian, Kamyar, Stockwell, Brent R.
Publicado 2022

CellDeathPred: a deep learning framework for ferroptosis and apoptosis prediction based on cell painting

por Schorpp, Kenji, Bessadok, Alaa, Biibosunov, Aidin, Rothenaigner, Ina, Strasser, Stefanie, Peng, Tingying, Hadian, Kamyar
Publicado 2023

ABCA3 Deficiency—Variant-Specific Response to Hydroxychloroquine

por Yang, Xiaohua, Forstner, Maria, Rapp, Christina K., Rothenaigner, Ina, Li, Yang, Hadian, Kamyar, Griese, Matthias
Publicado 2023

YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κB

por Schimmack, Gisela, Schorpp, Kenji, Kutzner, Kerstin, Gehring, Torben, Brenke, Jara Kerstin, Hadian, Kamyar, Krappmann, Daniel
Publicado 2017

A high-content small molecule screen identifies novel inducers of definitive endoderm

por Korostylev, Alexander, Mahaddalkar, Pallavi U., Keminer, Oliver, Hadian, Kamyar, Schorpp, Kenji, Gribbon, Philip, Lickert, Heiko
Publicado 2017

Unleashing high content screening in hit detection – Benchmarking AI workflows including novelty detection

por Kupczyk, Erwin, Schorpp, Kenji, Hadian, Kamyar, Lin, Sean, Tziotis, Dimitrios, Schmitt-Kopplin, Philippe, Mueller, Constanze
Publicado 2022

New Small Molecules Targeting Apoptosis and Cell Viability in Osteosarcoma

por Maugg, Doris, Rothenaigner, Ina, Schorpp, Kenji, Potukuchi, Harish Kumar, Korsching, Eberhard, Baumhoer, Daniel, Hadian, Kamyar, Smida, Jan, Nathrath, Michaela
Publicado 2015

Three‐dimensional microtissues essentially contribute to preclinical validations of therapeutic targets in breast cancer

por Falkenberg, Natalie, Höfig, Ines, Rosemann, Michael, Szumielewski, Justine, Richter, Sabine, Schorpp, Kenji, Hadian, Kamyar, Aubele, Michaela, Atkinson, Michael J., Anastasov, Nataša
Publicado 2016

Identification of Small-Molecule Frequent Hitters from AlphaScreen High-Throughput Screens

por Schorpp, Kenji, Rothenaigner, Ina, Salmina, Elena, Reinshagen, Jeanette, Low, Terence, Brenke, Jara K., Gopalakrishnan, Jay, Tetko, Igor V., Gul, Sheraz, Hadian, Kamyar
Publicado 2014

A 3D-microtissue-based phenotypic screening of radiation resistant tumor cells with synchronized chemotherapeutic treatment

por Anastasov, Nataša, Höfig, Ines, Radulović, Vanja, Ströbel, Simon, Salomon, Michael, Lichtenberg, Jan, Rothenaigner, Ina, Hadian, Kamyar, Kelm, Jens M., Thirion, Christian, Atkinson, Michael J.
Publicado 2015

Novel small molecules targeting ciliary transport of Smoothened and oncogenic Hedgehog pathway activation

por Jung, Bomi, Messias, Ana C., Schorpp, Kenji, Geerlof, Arie, Schneider, Günter, Saur, Dieter, Hadian, Kamyar, Sattler, Michael, Wanker, Erich E., Hasenöder, Stefan, Lickert, Heiko
Publicado 2016

Small molecule mediated inhibition of protein cargo recognition by peroxisomal transport receptor PEX5 is toxic to Trypanosoma

por Napolitano, Valeria, Softley, Charlotte A., Blat, Artur, Kalel, Vishal C., Schorpp, Kenji, Siebenmorgen, Till, Hadian, Kamyar, Erdmann, Ralf, Sattler, Michael, Popowicz, Grzegorz M., Dubin, Grzegorz
Publicado 2022

Sox2 controls Schwann cell self-organization through fibronectin fibrillogenesis

por Torres-Mejía, Elen, Trümbach, Dietrich, Kleeberger, Charlotte, Dornseifer, Ulf, Orschmann, Tanja, Bäcker, Theresa, Brenke, Jara Kerstin, Hadian, Kamyar, Wurst, Wolfgang, López-Schier, Hernán, Desbordes, Sabrina C.
Publicado 2020

Viral DNA Binding Protein SUMOylation Promotes PML Nuclear Body Localization Next to Viral Replication Centers

por Stubbe, Miona, Mai, Julia, Paulus, Christina, Stubbe, Hans Christian, Berscheminski, Julia, Karimi, Maryam, Hofmann, Samuel, Weber, Elisabeth, Hadian, Kamyar, Hay, Ron, Groitl, Peter, Nevels, Michael, Dobner, Thomas, Schreiner, Sabrina
Publicado 2020

Retinoic acid signaling is critical during the totipotency window in early mammalian development

por Iturbide, Ane, Ruiz Tejada Segura, Mayra L., Noll, Camille, Schorpp, Kenji, Rothenaigner, Ina, Ruiz-Morales, Elias R., Lubatti, Gabriele, Agami, Ahmed, Hadian, Kamyar, Scialdone, Antonio, Torres-Padilla, Maria-Elena
Publicado 2021

Author Correction: Retinoic acid signaling is critical during the totipotency window in early mammalian development

por Iturbide, Ane, Ruiz Tejada Segura, Mayra L., Noll, Camille, Schorpp, Kenji, Rothenaigner, Ina, Ruiz-Morales, Elias R., Lubatti, Gabriele, Agami, Ahmed, Hadian, Kamyar, Scialdone, Antonio, Torres-Padilla, Maria-Elena
Publicado 2022