Genetic Ablation of Nrf2/Antioxidant Response Pathway in Alexander Disease Mice Reduces Hippocampal Gliosis but Does Not Impact Survival

por Hagemann, Tracy L., Jobe, Emily M., Messing, Albee
Publicado 2012

GFAP expression as an indicator of disease severity in mouse models of Alexander disease

por Jany, Paige L., Hagemann, Tracy L., Messing, Albee
Publicado 2013

The effect of glial fibrillary acidic protein expression on neurite outgrowth from retinal explants in a permissive environment

por Toops, Kimberly A, Hagemann, Tracy L, Messing, Albee, Nickells, Robert W
Publicado 2012

STAT3 Drives GFAP Accumulation and Astrocyte Pathology in a Mouse Model of Alexander Disease

por Hagemann, Tracy L., Coyne, Sierra, Levin, Alder, Wang, Liqun, Feany, Mel B., Messing, Albee
Publicado 2023

Caspase cleavage of GFAP produces an assembly-compromised proteolytic fragment that promotes filament aggregation

por Chen, Mei-Hsuan, Hagemann, Tracy L., Quinlan, Roy A., Messing, Albee, Perng, Ming-Der
Publicado 2013

Nitric oxide mediates glial-induced neurodegeneration in Alexander disease

por Wang, Liqun, Hagemann, Tracy L., Kalwa, Hermann, Michel, Thomas, Messing, Albee, Feany, Mel B.
Publicado 2015

Pexidartinib treatment in Alexander disease model mice reduces macrophage numbers and increases glial fibrillary acidic protein levels, yet has minimal impact on other disease phen...

por Boyd, Michelle M., Litscher, Suzanne J., Seitz, Laura L., Messing, Albee, Hagemann, Tracy L., Collier, Lara S.
Publicado 2021

Tissue and cellular rigidity and mechanosensitive signaling activation in Alexander disease

por Wang, Liqun, Xia, Jing, Li, Jonathan, Hagemann, Tracy L., Jones, Jeffrey R., Fraenkel, Ernest, Weitz, David A., Zhang, Su-Chun, Messing, Albee, Feany, Mel B.
Publicado 2018