Disrupted expression of mitochondrial NCLX sensitizes neuroglial networks to excitotoxic stimuli and renders synaptic activity toxic

por Hagenston, Anna M., Yan, Jing, Bas-Orth, Carlos, Tan, Yanwei, Sekler, Israel, Bading, Hilmar
Publicado 2021

A microscopy-based small molecule screen in primary neurons reveals neuroprotective properties of the FDA-approved anti-viral drug Elvitegravir

por Merz, Simon F., Bengtson, C. Peter, Tepohl, Clara, Hagenston, Anna M., Bading, Hilmar, Bas-Orth, Carlos
Publicado 2020

Organic anion transporter 1 is an HDAC4-regulated mediator of nociceptive hypersensitivity in mice

por Litke, Christian, Hagenston, Anna M., Kenkel, Ann-Kristin, Paldy, Eszter, Lu, Jianning, Kuner, Rohini, Mauceri, Daniela
Publicado 2022

Epigenetic control of hypersensitivity in chronic inflammatory pain by the de novo DNA methyltransferase Dnmt3a2

por Oliveira, Ana MM, Litke, Christian, Paldy, Eszter, Hagenston, Anna M, Lu, Jianning, Kuner, Rohini, Bading, Hilmar, Mauceri, Daniela
Publicado 2019

A novel stem cell type at the basal side of the subventricular zone maintains adult neurogenesis

por Baur, Katja, Abdullah, Yomn, Mandl, Claudia, Hölzl‐Wenig, Gabriele, Shi, Yan, Edelkraut, Udo, Khatri, Priti, Hagenston, Anna M, Irmler, Martin, Beckers, Johannes, Ciccolini, Francesca
Publicado 2022

Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals

por Qiu, Jing, Tan, Yan-Wei, Hagenston, Anna M., Martel, Marc-Andre, Kneisel, Niclas, Skehel, Paul A., Wyllie, David J. A., Bading, Hilmar, Hardingham, Giles E.
Publicado 2013

EphB2-dependent signaling promotes neuronal excitotoxicity and inflammation in the acute phase of ischemic stroke

por Ernst, Anne-Sophie, Böhler, Laura-Inés, Hagenston, Anna M., Hoffmann, Angelika, Heiland, Sabine, Sticht, Carsten, Bendszus, Martin, Hecker, Markus, Bading, Hilmar, Marti, Hugo H., Korff, Thomas, Kunze, Reiner
Publicado 2019

Brain-enriched RagB isoforms regulate the dynamics of mTORC1 activity through GATOR1 inhibition

por Figlia, Gianluca, Müller, Sandra, Hagenston, Anna M., Kleber, Susanne, Roiuk, Mykola, Quast, Jan-Philipp, ten Bosch, Nora, Carvajal Ibañez, Damian, Mauceri, Daniela, Martin-Villalba, Ana, Teleman, Aurelio A.
Publicado 2022

Neuronal nuclear calcium signaling suppression of microglial reactivity is mediated by osteoprotegerin after traumatic brain injury

por Fröhlich, Albrecht, Olde Heuvel, Florian, Rehman, Rida, Krishnamurthy, Sruthi Sankari, Li, Shun, Li, Zhenghui, Bayer, David, Conquest, Alison, Hagenston, Anna M., Ludolph, Albert, Huber-Lang, Markus, Boeckers, Tobias, Knöll, Bernd, Morganti-Kossmann, Maria Cristina, Bading, Hilmar, Roselli, Francesco
Publicado 2022