Inflammatory Mediators in Intervertebral Disk Degeneration and Discogenic Pain

por Wuertz, Karin, Haglund, Lisbet
Publicado 2013

Low-Frequency High-Magnitude Mechanical Strain of Articular Chondrocytes Activates p38 MAPK and Induces Phenotypic Changes Associated with Osteoarthritis and Pain

por Rosenzweig, Derek H., Quinn, Thomas M., Haglund, Lisbet
Publicado 2014

Maintenance of cell viability in axially loaded intervertebral disc organ culture

por Awwad, Waleed, Steffen, Thomas, Roughley, Peter, Haglund, Lisbet, Ouellet, Jean
Publicado 2011

3D-Printed ABS and PLA Scaffolds for Cartilage and Nucleus Pulposus Tissue Regeneration

por Rosenzweig, Derek H., Carelli, Eric, Steffen, Thomas, Jarzem, Peter, Haglund, Lisbet
Publicado 2015

o-Vanillin Modulates Cell Phenotype and Extracellular Vesicles of Human Mesenchymal Stem Cells and Intervertebral Disc Cells

por Li, Li, Sheng, Kai, Mannarino, Matthew, Jarzem, Peter, Cherif, Hosni, Haglund, Lisbet
Publicado 2022

Physiological Loading Can Restore the Proteoglycan Content in a Model of Early IVD Degeneration

por Gawri, Rahul, Moir, Janet, Ouellet, Jean, Beckman, Lorne, Steffen, Thomas, Roughley, Peter, Haglund, Lisbet
Publicado 2014

Curcumin and o-Vanillin Exhibit Evidence of Senolytic Activity in Human IVD Cells In Vitro

por Cherif, Hosni, Bisson, Daniel G., Jarzem, Peter, Weber, Michael, Ouellet, Jean A., Haglund, Lisbet
Publicado 2019

Senotherapeutic drugs for human intervertebral disc degeneration and low back pain

por Cherif, Hosni, Bisson, Daniel G, Mannarino, Matthew, Rabau, Oded, Ouellet, Jean A, Haglund, Lisbet
Publicado 2020

The effect of Link N on differentiation of human bone marrow-derived mesenchymal stem cells

por Antoniou, John, Wang, Hong Tian, Alaseem, Abdulrahman M, Haglund, Lisbet, Roughley, Peter J, Mwale, Fackson
Publicado 2012

Toll-like Receptor Activation Induces Degeneration of Human Intervertebral Discs

por Krock, Emerson, Rosenzweig, Derek H., Currie, J. Brooke, Bisson, Daniel G., Ouellet, Jean A., Haglund, Lisbet
Publicado 2017

Single-Cell RNA-Seq Analysis of Cells from Degenerating and Non-Degenerating Intervertebral Discs from the Same Individual Reveals New Biomarkers for Intervertebral Disc Degenerati...

por Cherif, Hosni, Mannarino, Matthew, Pacis, Alain Sarabia, Ragoussis, Jiannis, Rabau, Oded, Ouellet, Jean A., Haglund, Lisbet
Publicado 2022

High mechanical strain of primary intervertebral disc cells promotes secretion of inflammatory factors associated with disc degeneration and pain

por Gawri, Rahul, Rosenzweig, Derek H, Krock, Emerson, Ouellet, Jean A, Stone, Laura S, Quinn, Thomas M, Haglund, Lisbet
Publicado 2014

Facet joint degeneration in adolescent idiopathic scoliosis

por G. Bisson, Daniel, Lama, Polly, Abduljabbar, Fahad, Rosenzweig, Derek H., Saran, Neil, Ouellet, Jean A., Haglund, Lisbet
Publicado 2018

Mesenchymal Stem Cell Homing Into Intervertebral Discs Enhances the Tie2-positive Progenitor Cell Population, Prevents Cell Death, and Induces a Proliferative Response

por Wangler, Sebastian, Peroglio, Marianna, Menzel, Ursula, Benneker, Lorin M., Haglund, Lisbet, Sakai, Daisuke, Alini, Mauro, Grad, Sibylle
Publicado 2019

Toll‐like receptor involvement in adolescent scoliotic facet joint degeneration

por Bisson, Daniel G., Sheng, Kai, Kocabas, Semsi, Krock, Emerson, Teles, Alisson, Saran, Neil, Ouellet, Jean A., Haglund, Lisbet
Publicado 2020

DNA methylation of SPARC and chronic low back pain

por Tajerian, Maral, Alvarado, Sebastian, Millecamps, Magali, Dashwood, Thomas, Anderson, Kathleen M, Haglund, Lisbet, Ouellet, Jean, Szyf, Moshe, Stone, Laura S
Publicado 2011

Low-dose zoledronate for the treatment of bone metastasis secondary to prostate cancer

por Akoury, Elie, Ahangar, Pouyan, Nour, Antone, Lapointe, Jacques, Guérard, Karl-Philippe, Haglund, Lisbet, Rosenzweig, Derek H., Weber, Michael H.
Publicado 2019

Toll-like receptor 2 induced senescence in intervertebral disc cells of patients with back pain can be attenuated by o-vanillin

por Mannarino, Matthew, Cherif, Hosni, Li, Li, Sheng, Kai, Rabau, Oded, Jarzem, Peter, Weber, Michael H., Ouellet, Jean A., Haglund, Lisbet
Publicado 2021

Senolytic Combination Treatment Is More Potent Than Single Drugs in Reducing Inflammatory and Senescence Burden in Cells from Painful Degenerating IVDs

por Mannarino, Matthew, Wu-Martinez, Oliver, Sheng, Kai, Li, Li, Navarro-Ramirez, Rodrigo, Jarzem, Peter, Ouellet, Jean A., Cherif, Hosni, Haglund, Lisbet
Publicado 2023

Painful, degenerating intervertebral discs up-regulate neurite sprouting and CGRP through nociceptive factors

por Krock, Emerson, Rosenzweig, Derek H, Chabot-Doré, Anne-Julie, Jarzem, Peter, Weber, Michael H, Ouellet, Jean A, Stone, Laura S, Haglund, Lisbet
Publicado 2014