Constellation Map: Downstream visualization and interpretation of gene set enrichment results

por Tan, Yan, Wu, Felix, Tamayo, Pablo, Haining, W. Nicholas, Mesirov, Jill P.
Publicado 2015

Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates

por Sarkar, Surojit, Kalia, Vandana, Haining, W. Nicholas, Konieczny, Bogumila T., Subramaniam, Shruti, Ahmed, Rafi
Publicado 2008

CD28 Costimulation Regulates Genome-Wide Effects on Alternative Splicing

por Butte, Manish J., Lee, Sun Jung, Jesneck, Jonathan, Keir, Mary E., Haining, W. Nicholas, Sharpe, Arlene H.
Publicado 2012

Early Effector CD8 T Cells Display Plasticity in Populating the Short-Lived Effector and Memory-Precursor Pools Following Bacterial or Viral Infection

por Plumlee, Courtney R., Obar, Joshua J., Colpitts, Sara L., Jellison, Evan R., Haining, W. Nicholas, Lefrancois, Leo, Khanna, Kamal M.
Publicado 2015

High-throughput gene expression profiling of memory differentiation in primary human T cells

por Haining, W Nicholas, Angelosanto, Jill, Brosnahan, Kathleen, Ross, Kenneth, Hahn, Cynthia, Russell, Kate, Drury, Linda, Norton, Stephanie, Nadler, Lee, Stegmaier, Kimberly
Publicado 2008

PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity

por Juneja, Vikram R., McGuire, Kathleen A., Manguso, Robert T., LaFleur, Martin W., Collins, Natalie, Haining, W. Nicholas, Freeman, Gordon J., Sharpe, Arlene H.
Publicado 2017

Coregulation of CD8(+) T cell exhaustion during chronic viral infection by multiple inhibitory receptors

por Blackburn, Shawn D., Shin, Haina, Haining, W. Nicholas, Zou, Tao, Workman, Creg J., Polley, Antonio, Betts, Michael R., Freeman, Gordon J., Vignali, Dario A. A., Wherry, E. John
Publicado 2008

The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8(+) T cells

por Kurachi, Makoto, Barnitz, R. Anthony, Yosef, Nir, Odorizzi, Pamela M., Dilorio, Michael A., Lemieux, Madeleine E., Yates, Kathleen, Godec, Jernej, Klatt, Martin G., Regev, Aviv, Wherry, E. John, Haining, W. Nicholas
Publicado 2014

Targeted reconstruction of T cell receptor sequence from single cell RNA-seq links CDR3 length to T cell differentiation state

por Afik, Shaked, Yates, Kathleen B., Bi, Kevin, Darko, Samuel, Godec, Jernej, Gerdemann, Ulrike, Swadling, Leo, Douek, Daniel C., Klenerman, Paul, Barnes, Eleanor J., Sharpe, Arlene H., Haining, W. Nicholas, Yosef, Nir
Publicado 2017

A CRISPR-Cas9 delivery system for in vivo screening of genes in the immune system

por LaFleur, Martin W., Nguyen, Thao H., Coxe, Matthew A., Yates, Kathleen B., Trombley, Justin D., Weiss, Sarah A., Brown, Flavian D., Gillis, Jacob E., Coxe, Daniel J., Doench, John G., Haining, W. Nicholas, Sharpe, Arlene H.
Publicado 2019

PTPN2 regulates the generation of exhausted CD8(+) T cell subpopulations and restrains tumor immunity

por LaFleur, Martin W., Nguyen, Thao H., Coxe, Matthew A., Miller, Brian C., Yates, Kathleen B., Gillis, Jacob E., Sen, Debattama R., Gaudiano, Emily F., Abosy, Rose Al, Freeman, Gordon J., Haining, W. Nicholas, Sharpe, Arlene H.
Publicado 2019

The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells

por Beyaz, Semir, Kim, Ji Hyung, Pinello, Luca, Xifaras, Michael E., Hu, Yu, Huang, Jialiang, Kerenyi, Marc A., Das, Partha P., Barnitz, R. Anthony, Herault, Aurelie, Dogum, Rizkullah, Haining, W. Nicholas, Yilmaz, Ömer H., Passegue, Emmanuelle, Yuan, Guo-Cheng, Orkin, Stuart H., Winau, Florian
Publicado 2016

Epigenetic Features of HIV-Induced T-Cell Exhaustion Persist Despite Early Antiretroviral Therapy

por Martin, Genevieve E., Sen, Debattama R., Pace, Matthew, Robinson, Nicola, Meyerowitz, Jodi, Adland, Emily, Thornhill, John P., Jones, Mathew, Ogbe, Ane, Parolini, Lucia, Olejniczak, Natalia, Zacharopoulou, Panagiota, Brown, Helen, Willberg, Christian B., Nwokolo, Nneka, Fox, Julie, Fidler, Sarah, Haining, W. Nicholas, Frater, John
Publicado 2021

Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion

por Battistello, Elena, Hixon, Kimberlee A., Comstock, Dawn E., Collings, Clayton K., Chen, Xufeng, Hernaez, Javier Rodriguez, Lee, Soobeom, Cervantes, Kasey S., Hinkley, Madeline M., Ntatsoulis, Konstantinos, Cesarano, Annamaria, Hockemeyer, Kathryn, Haining, W. Nicholas, Witkowski, Matthew T., Qi, Jun, Tsirigos, Aristotelis, Perna, Fabiana, Aifantis, Iannis, Kadoch, Cigall
Publicado 2023

CD39 Expression Identifies Terminally Exhausted CD8(+) T Cells

por Gupta, Prakash K., Godec, Jernej, Wolski, David, Adland, Emily, Yates, Kathleen, Pauken, Kristen E., Cosgrove, Cormac, Ledderose, Carola, Junger, Wolfgang G., Robson, Simon C., Wherry, E. John, Alter, Galit, Goulder, Philip J. R., Klenerman, Paul, Sharpe, Arlene H., Lauer, Georg M., Haining, W. Nicholas
Publicado 2015

Recapitulating adult human immune traits in laboratory mice by normalizing environment

por Beura, Lalit K., Hamilton, Sara E., Bi, Kevin, Schenkel, Jason M., Odumade, Oludare A., Casey, Kerry A., Thompson, Emily A., Fraser, Kathryn A., Rosato, Pamela C., Filali-Mouhim, Ali, Sekaly, Rafick P., Jenkins, Marc K., Vezys, Vaiva, Haining, W. Nicholas, Jameson, Stephen C., Masopust, David
Publicado 2016

PI3K activation allows immune evasion by promoting an inhibitory myeloid tumor microenvironment

por Collins, Natalie B, Al Abosy, Rose, Miller, Brian C, Bi, Kevin, Zhao, Qihong, Quigley, Michael, Ishizuka, Jeffrey J, Yates, Kathleen B, Pope, Hans W, Manguso, Robert T, Shrestha, Yashaswi, Wadsworth, Marc, Hughes, Travis, Shalek, Alex K, Boehm, Jesse S, Hahn, William C, Doench, John G, Haining, W Nicholas
Publicado 2022

Systems Biology of Seasonal Influenza Vaccination in Humans

por Nakaya, Helder I, Wrammert, Jens, Lee, Eva K, Racioppi, Luigi, Marie-Kunze, Stephanie, Haining, W. Nicholas, Means, Anthony R, Kasturi, Sudhir P, Khan, Nooruddin, Li, Gui-Mei, McCausland, Megan, Kanchan, Vibhu, Kokko, Kenneth E, Li, Shuzhao, Elbein, Rivka, Mehta, Aneesh K, Aderem, Alan, Subbarao, Kanta, Ahmed, Rafi, Pulendran, Bali
Publicado 2011

Integrative genomic analysis of HIV-specific CD8(+) T cells reveals that PD-1 inhibits T cell function by upregulating BATF

por Quigley, Michael, Pereyra, Florencia, Nilsson, Björn, Porichis, Filippos, Fonseca, Catia, Eichbaum, Quentin, Julg, Boris, Jesneck, Jonathan L., Brosnahan, Kathleen, Imam, Sabrina, Russell, Kate, Toth, Ildiko, Piechocka-Trocha, Alicja, Dolfi, Douglas, Angelosanto, Jill, Crawford, Alison, Shin, Haina, Kwon, Douglas S., Zupkosky, Jennifer, Francisco, Loise, Freeman, Gordon J., Wherry, E. John, Kaufmann, Daniel E., Walker, Bruce D., Ebert, Benjamin, Haining, W. Nicholas
Publicado 2010

Differentiation of exhausted CD8 T cells after termination of chronic antigen stimulation stops short of achieving functional T cell memory

por Tonnerre, Pierre, Wolski, David, Subudhi, Sonu, Al-Jabban, Jihad, Hoogeveen, Ruben C., Damasio, Marcos, Drescher, Hannah K., Bartsch, Lea M., Tully, Damien C., Sen, Debattama R., Bean, David J., Brown, Joelle, Torres-Cornejo, Almudena, Robidoux, Maxwell, Kvistad, Daniel, Alatrakchi, Nadia, Cui, Ang, Lieb, David, Cheney, James A., Gustafson, Jenna, Lewis-Ximenez, Lia L, Massenet-Regad, Lucile, Eisenhaure, Thomas, Aneja, Jasneet, Haining, W. Nicholas, Chung, Raymond T., Hacohen, Nir, Allen, Todd M., Kim, Arthur Y., Lauer, Georg M.
Publicado 2021