Do apicomplexan parasites hijack the host cell microRNA pathway for their intracellular development?

por Hakimi, Mohamed-Ali, Ménard, Robert
Publicado 2010

Sustained Egr-1 Response via p38 MAP Kinase Signaling Modulates Early Immune Responses of Dendritic Cells Parasitized by Toxoplasma gondii

por ten Hoeve, Arne L., Hakimi, Mohamed-Ali, Barragan, Antonio
Publicado 2019

Toxoplasma gondii peroxiredoxin promotes altered macrophage function, caspase-1-dependent IL-1β secretion enhances parasite replication

por Marshall, Edward S, Elshekiha, Hany M, Hakimi, Mohamed-Ali, Flynn, Robin J
Publicado 2011

How Fitch-Margoliash Algorithm can Benefit from Multi Dimensional Scaling

por Lespinats, Sylvain, Grando, Delphine, Maréchal, Eric, Hakimi, Mohamed-Ali, Tenaillon, Olivier, Bastien, Olivier
Publicado 2011

UAP56 associates with DRM2 and is localized to chromatin in Arabidopsis

por Azevedo, Jacinthe, Picart, Claire, Dureau, Laurent, Pontier, Dominique, Jaquinod‐Kieffer, Sylvie, Hakimi, Mohamed‐Ali, Lagrange, Thierry
Publicado 2019

A Critical Role for Toxoplasma gondii Vacuolar Protein Sorting VPS9 in Secretory Organelle Biogenesis and Host Infection

por Sakura, Takaya, Sindikubwabo, Fabien, Oesterlin, Lena K., Bousquet, Hugo, Slomianny, Christian, Hakimi, Mohamed-Ali, Langsley, Gordon, Tomavo, Stanislas
Publicado 2016

Structural Basis for the Subversion of MAP Kinase Signaling by an Intrinsically Disordered Parasite Secreted Agonist

por Pellegrini, Erika, Palencia, Andrés, Braun, Laurence, Kapp, Ulrike, Bougdour, Alexandre, Belrhali, Hassan, Bowler, Matthew W., Hakimi, Mohamed-Ali
Publicado 2017

Target Identification of an Antimalarial Oxaborole Identifies AN13762 as an Alternative Chemotype for Targeting CPSF3 in Apicomplexan Parasites

por Bellini, Valeria, Swale, Christopher, Brenier-Pinchart, Marie-Pierre, Pezier, Tiffany, Georgeault, Sonia, Laurent, Fabrice, Hakimi, Mohamed-Ali, Bougdour, Alexandre
Publicado 2020

Characterization of a Toxoplasma effector uncovers an alternative GSK3/β-catenin-regulatory pathway of inflammation

por He, Huan, Brenier-Pinchart, Marie-Pierre, Braun, Laurence, Kraut, Alexandra, Touquet, Bastien, Couté, Yohann, Tardieux, Isabelle, Hakimi, Mohamed-Ali, Bougdour, Alexandre
Publicado 2018

Double drugging of prolyl-tRNA synthetase provides a new paradigm for anti-infective drug development

por Manickam, Yogavel, Malhotra, Nipun, Mishra, Siddhartha, Babbar, Palak, Dusane, Abhishek, Laleu, Benoît, Bellini, Valeria, Hakimi, Mohamed-Ali, Bougdour, Alexandre, Sharma, Amit
Publicado 2022

Drug inhibition of HDAC3 and epigenetic control of differentiation in Apicomplexa parasites

por Bougdour, Alexandre, Maubon, Danièle, Baldacci, Patricia, Ortet, Philippe, Bastien, Olivier, Bouillon, Anthony, Barale, Jean-Christophe, Pelloux, Hervé, Ménard, Robert, Hakimi, Mohamed-Ali
Publicado 2009

A Complex Small RNA Repertoire Is Generated by a Plant/Fungal-Like Machinery and Effected by a Metazoan-Like Argonaute in the Single-Cell Human Parasite Toxoplasma gondii

por Braun, Laurence, Cannella, Dominique, Ortet, Philippe, Barakat, Mohamed, Sautel, Céline F., Kieffer, Sylvie, Garin, Jérôme, Bastien, Olivier, Voinnet, Olivier, Hakimi, Mohamed-Ali
Publicado 2010

Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis

por Yogavel, Manickam, Bougdour, Alexandre, Mishra, Siddhartha, Malhotra, Nipun, Chhibber-Goel, Jyoti, Bellini, Valeria, Harlos, Karl, Laleu, Benoît, Hakimi, Mohamed-Ali, Sharma, Amit
Publicado 2023

Assembly of the Novel Five-Component Apicomplexan Multi-Aminoacyl-tRNA Synthetase Complex Is Driven by the Hybrid Scaffold Protein Tg-p43

por van Rooyen, Jason M., Murat, Jean-Benjamin, Hammoudi, Pierre-Mehdi, Kieffer-Jaquinod, Sylvie, Coute, Yohann, Sharma, Amit, Pelloux, Hervé, Belrhali, Hassan, Hakimi, Mohamed-Ali
Publicado 2014

Dual role of the Toxoplasma gondii clathrin adaptor AP1 in the sorting of rhoptry and microneme proteins and in parasite division

por Venugopal, Kannan, Werkmeister, Elisabeth, Barois, Nicolas, Saliou, Jean-Michel, Poncet, Anais, Huot, Ludovic, Sindikubwabo, Fabien, Hakimi, Mohamed Ali, Langsley, Gordon, Lafont, Frank, Marion, Sabrina
Publicado 2017

Multi-omics analysis delineates the distinct functions of sub-cellular acetyl-CoA pools in Toxoplasma gondii

por Kloehn, Joachim, Oppenheim, Rebecca D., Siddiqui, Ghizal, De Bock, Pieter-Jan, Kumar Dogga, Sunil, Coute, Yohann, Hakimi, Mohamed-Ali, Creek, Darren J., Soldati-Favre, Dominique
Publicado 2020

A brain cyst load-associated antigen is a Toxoplasma gondii biomarker for serodetection of persistent parasites and chronic infection

por Dard, Céline, Swale, Christopher, Brenier-Pinchart, Marie-Pierre, Farhat, Dayana C., Bellini, Valeria, Robert, Marie Gladys, Cannella, Dominique, Pelloux, Hervé, Tardieux, Isabelle, Hakimi, Mohamed-Ali
Publicado 2021

A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental gene partitioning in Toxoplasma

por Farhat, Dayana C, Bowler, Matthew W, Communie, Guillaume, Pontier, Dominique, Belmudes, Lucid, Mas, Caroline, Corrao, Charlotte, Couté, Yohann, Bougdour, Alexandre, Lagrange, Thierry, Hakimi, Mohamed-Ali, Swale, Christopher
Publicado 2021

Evidence for ARGONAUTE4–DNA interactions in RNA-directed DNA methylation in plants

por Lahmy, Sylvie, Pontier, Dominique, Bies-Etheve, Natacha, Laudié, Michèle, Feng, Suhua, Jobet, Edouard, Hale, Christopher J., Cooke, Richard, Hakimi, Mohamed-Ali, Angelov, Dimitar, Jacobsen, Steven E., Lagrange, Thierry
Publicado 2016

A MORC-driven transcriptional switch controls Toxoplasma developmental trajectories and sexual commitment

por Farhat, Dayana C., Swale, Christopher, Dard, Céline, Cannella, Dominique, Ortet, Philippe, Barakat, Mohamed, Sindikubwabo, Fabien, Belmudes, Lucid, De Bock, Pieter-Jan, Couté, Yohann, Bougdour, Alexandre, Hakimi, Mohamed-Ali
Publicado 2020