Analytic validation and clinical utilization of the comprehensive genomic profiling test, GEM ExTra(®)

por White, Tracey, Szelinger, Szabolcs, LoBello, Janine, King, Amy, Aldrich, Jessica, Garinger, Nathan, Halbert, Matthew, Richholt, Ryan F., Mastrian, Stephen D., Babb, Cody, Ozols, Audrey A., Goodman, Laurie J., Basu, Gargi D., Royce, Thomas
Publicado 2021

DIPG-36. H3K27M HISTONE MUTANT GLIOMAS ARE SENSITIVE TO METHIONINE LOSS AND MAT2A INHIBITION THROUGH A NOVEL FEEDBACK MECHANISM BETWEEN AMD1 AND METTL16

por Chilukuri, Akanksha, Halbert, Matthew, Golbourn, Brian, Varadharajan, Srinidhi, Krug, Brian, Mbah, Nneka, Casillo, Stephanie, Gatesman, Taylor, Cruz, Andrea, Zapotocky, Michael, Hu, Baoli, Kohanbash, Gary, Bertrand, Kelsey, Kleinman, Claudia, Lyssiotis, Costas, Jabado, Nada, Pollack, Ian, Mack, Stephen, Agnihotri, Sameer
Publicado 2023

Targeting mitochondrial energetics reverses panobinostat‐ and marizomib‐induced resistance in pediatric and adult high‐grade gliomas

por Jane, Esther P., Reslink, Matthew C., Gatesman, Taylor A., Halbert, Matthew E., Miller, Tracy A., Golbourn, Brian J., Casillo, Stephanie M., Mullett, Steven J., Wendell, Stacy G., Obodo, Udochukwu, Mohanakrishnan, Dinesh, Dange, Riya, Michealraj, Antony, Brenner, Charles, Agnihotri, Sameer, Premkumar, Daniel R., Pollack, Ian F.
Publicado 2023

Sorting nexin 10 sustains PDGF receptor signaling in glioblastoma stem cells via endosomal protein sorting

por Gimple, Ryan C., Zhang, Guoxin, Wang, Shuai, Huang, Tengfei, Lee, Jina, Taori, Suchet, Lv, Deguan, Dixit, Deobrat, Halbert, Matthew E., Morton, Andrew R., Kidwell, Reilly L., Dong, Zhen, Prager, Briana C., Kim, Leo J.Y., Qiu, Zhixin, Zhao, Linjie, Xie, Qi, Wu, Qiulian, Agnihotri, Sameer, Rich, Jeremy N.
Publicado 2023

DIPG-46. TARGETING THE METABOLIC ERK5-PFKFB3 AXIS IN PEDIATRIC DIFFUSE MIDLINE GLIOMA

por Casillo, Stephanie, Gatesman, Taylor, Chilukuri, Akanksha, Jane, Esther, Premkumar, Daniel, Barber, Callie, Halbert, Matthew, Cruz, Andrea, Mullett, Steven, Michel, Joshua, Chang, Yue-Fang, MichaelRaj, Antony, Lieberman, Frank, Felker, James, Shiva, Sruti, Abdullah, Kalil, Zinn, Pascal, Friedlander, Robert, Abel, Taylor, Venneti, Sriram, Mack, Stephen, Wendell, Stacy, Pollack, Ian, Agnihotri, Sameer
Publicado 2023

DIPG-08. THE LANDSCAPE OF TUMOR CELL STATES AND SPATIAL ORGANIZATION IN H3-K27M MUTANT DIFFUSE MIDLINE GLIOMA ACROSS AGE AND LOCATION

por Liu, Ilon, Jiang, Li, Samuelsson, Erik, Salas, Sergio Marco, Beck, Alexander, Hack, Olivia, Jeong, Daeun, Shaw, McKenzie, Englinger, Bernhard, LaBelle, Jenna, Mire, Hafsa, Madlener, Sibylle, Mayr, Lisa, Quezada, Michael, Trissal, Maria, Panditharatna, Eshini, Ernst, Kati, Vogelzang, Jayne, Gatesman, Taylor, Halbert, Matthew, Palova, Hana, Vesela, Petra, Sterba, Jaroslav, Slaby, Ondrej, Geyeregger, Rene, Diaz, Aaron, Findlay, Izac, Dun, Matt, Resnick, Adam, Suva, Mario, Jones, David, Agnihotri, Sameer, Ostlin, Jessica, Koschmann, Carl, Haberler, Christine, Czech, Thomas, Slavc, Irene, Cotter, Jennifer, Ligon, Keith, Alexandrescu, Sanda, Yung, W K Alfred, Arrillaga-Romany, Isabel, Gojo, Johannes, Monje, Michelle, Nilsson, Mats, Filbin, Mariella
Publicado 2023

The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location

por Liu, Ilon, Jiang, Li, Samuelsson, Erik R., Marco Salas, Sergio, Beck, Alexander, Hack, Olivia A., Jeong, Daeun, Shaw, McKenzie L., Englinger, Bernhard, LaBelle, Jenna, Mire, Hafsa M., Madlener, Sibylle, Mayr, Lisa, Quezada, Michael A., Trissal, Maria, Panditharatna, Eshini, Ernst, Kati J., Vogelzang, Jayne, Gatesman, Taylor A., Halbert, Matthew E., Palova, Hana, Pokorna, Petra, Sterba, Jaroslav, Slaby, Ondrej, Geyeregger, Rene, Diaz, Aaron, Findlay, Izac J., Dun, Matthew D., Resnick, Adam, Suvà, Mario L., Jones, David T. W., Agnihotri, Sameer, Svedlund, Jessica, Koschmann, Carl, Haberler, Christine, Czech, Thomas, Slavc, Irene, Cotter, Jennifer A., Ligon, Keith L., Alexandrescu, Sanda, Yung, W. K. Alfred, Arrillaga-Romany, Isabel, Gojo, Johannes, Monje, Michelle, Nilsson, Mats, Filbin, Mariella G.
Publicado 2022