BRD4 inhibition for the treatment of pathological organ fibrosis

por Stratton, Matthew S., Haldar, Saptarsi M., McKinsey, Timothy A.
Publicado 2017

Transcription factors KLF15 and PPARδ cooperatively orchestrate genome-wide regulation of lipid metabolism in skeletal muscle

por Fan, Liyan, Sweet, David R., Fan, Erica K., Prosdocimo, Domenick A., Madera, Annmarie, Jiang, Zhen, Padmanabhan, Roshan, Haldar, Saptarsi M., Vinayachandran, Vinesh, Jain, Mukesh K.
Publicado 2022

Molecular mechanisms of coronary artery disease risk at the PDGFD locus

por Kim, Hyun-Jung, Cheng, Paul, Travisano, Stanislao, Weldy, Chad, Monteiro, João P., Kundu, Ramendra, Nguyen, Trieu, Sharma, Disha, Shi, Huitong, Lin, Yi, Liu, Boxiang, Haldar, Saptarsi, Jackson, Simon, Quertermous, Thomas
Publicado 2023

Molecular mechanisms of coronary artery disease risk at the PDGFD locus

por Kim, Hyun-Jung, Cheng, Paul, Travisano, Stanislao, Weldy, Chad, Monteiro, João P., Kundu, Ramendra, Nguyen, Trieu, Sharma, Disha, Shi, Huitong, Lin, Yi, Liu, Boxiang, Haldar, Saptarsi, Jackson, Simon, Quertermous, Thomas
Publicado 2023

KLF15 cistromes reveal a hepatocyte pathway governing plasma corticosteroid transport and systemic inflammation

por Jiang, Zhen, Elsarrag, Selma Z., Duan, Qiming, LaGory, Edward L., Wang, Zhe, Alexanian, Michael, McMahon, Sarah, Rulifson, Ingrid C., Winchester, Sarah, Wang, Yi, Vaisse, Christian, Brown, Jonathan D., Quattrocelli, Mattia, Lin, Charles Y., Haldar, Saptarsi M.
Publicado 2022

BET bromodomain proteins regulate enhancer function during adipogenesis

por Brown, Jonathan D., Feldman, Zachary B., Doherty, Sean P., Reyes, Jaime M., Rahl, Peter B., Lin, Charles Y., Sheng, Quanhu, Duan, Qiong, Federation, Alexander J., Kung, Andrew L., Haldar, Saptarsi M., Young, Richard A., Plutzky, Jorge, Bradner, James E.
Publicado 2018

Targeting transcription in heart failure via CDK7/12/13 inhibition

por Hsu, Austin, Duan, Qiming, Day, Daniel S., Luo, Xin, McMahon, Sarah, Huang, Yu, Feldman, Zachary B., Jiang, Zhen, Zhang, Tinghu, Liang, Yanke, Alexanian, Michael, Padmanabhan, Arun, Brown, Jonathan D., Lin, Charles Y., Gray, Nathanael S., Young, Richard A., Bruneau, Benoit G., Haldar, Saptarsi M.
Publicado 2022

Circadian rhythms govern cardiac repolarization and arrhythmogenesis

por Jeyaraj, Darwin, Haldar, Saptarsi M., Wan, Xiaoping, McCauley, Mark D., Ripperger, Jürgen A., Hu, Kun, Lu, Yuan, Eapen, Betty L., Sharma, Nikunj, Ficker, Eckhard, Cutler, Michael J., Gulick, James, Sanbe, Atsushi, Robbins, Jeffrey, Demolombe, Sophie, Kondratov, Roman V., Shea, Steven A., Albrecht, Urs, Wehrens, Xander H.T., Rosenbaum, David S., Jain, Mukesh K.
Publicado 2012

Interventions Targeting Glucocorticoid-Krüppel-like Factor 15-Branched-Chain Amino Acid Signaling Improve Disease Phenotypes in Spinal Muscular Atrophy Mice

por Walter, Lisa M., Deguise, Marc-Olivier, Meijboom, Katharina E., Betts, Corinne A., Ahlskog, Nina, van Westering, Tirsa L.E., Hazell, Gareth, McFall, Emily, Kordala, Anna, Hammond, Suzan M., Abendroth, Frank, Murray, Lyndsay M., Shorrock, Hannah K., Prosdocimo, Domenick A., Haldar, Saptarsi M., Jain, Mukesh K., Gillingwater, Thomas H., Claus, Peter, Kothary, Rashmi, Wood, Matthew J.A., Bowerman, Melissa
Publicado 2018

Chromatin Remodeling Drives Immune-Fibroblast Crosstalk in Heart Failure Pathogenesis

por Alexanian, Michael, Padmanabhan, Arun, Nishino, Tomohiro, Travers, Joshua G., Ye, Lin, Lee, Clara Youngna, Sadagopan, Nandhini, Huang, Yu, Pelonero, Angelo, Auclair, Kirsten, Zhu, Ada, Teran, Barbara Gonzalez, Flanigan, Will, Kim, Charis Kee-Seon, Lumbao-Conradson, Koya, Costa, Mauro, Jain, Rajan, Charo, Israel, Haldar, Saptarsi M., Pollard, Katherine S., Vagnozzi, Ronald J., McKinsey, Timothy A., Przytycki, Pawel F., Srivastava, Deepak
Publicado 2023