Prediction of Burkholderia pseudomallei DsbA substrates identifies potential virulence factors and vaccine targets

por Vezina, Ben, Petit, Guillaume A., Martin, Jennifer L., Halili, Maria A.
Publicado 2020

Rv2969c, essential for optimal growth in Mycobacterium tuberculosis, is a DsbA-like enzyme that interacts with VKOR-derived peptides and has atypical features of DsbA-like disulfid...

por Premkumar, Lakshmanane, Heras, Begoña, Duprez, Wilko, Walden, Patricia, Halili, Maria, Kurth, Fabian, Fairlie, David P., Martin, Jennifer L.
Publicado 2013

The α-Proteobacteria Wolbachia pipientis Protein Disulfide Machinery Has a Regulatory Mechanism Absent in γ-Proteobacteria

por Walden, Patricia M., Halili, Maria A., Archbold, Julia K., Lindahl, Fredrik, Fairlie, David P., Inaba, Kenji, Martin, Jennifer L.
Publicado 2013

The atypical thiol–disulfide exchange protein α-DsbA2 from Wolbachia pipientis is a homotrimeric disulfide isomerase

por Walden, Patricia M., Whitten, Andrew E., Premkumar, Lakshmanane, Halili, Maria A., Heras, Begoña, King, Gordon J., Martin, Jennifer L.
Publicado 2019

Oxidoreductase disulfide bond proteins DsbA and DsbB form an active redox pair in Chlamydia trachomatis, a bacterium with disulfide dependent infection and development

por Christensen, Signe, Halili, Maria A., Strange, Natalie, Petit, Guillaume A., Huston, Wilhelmina M., Martin, Jennifer L., McMahon, Róisín M.
Publicado 2019

The Glitazone Class of Drugs as Carbonic Anhydrase Inhibitors—A Spin-Off Discovery from Fragment Screening

por Mueller, Sarah L., Chrysanthopoulos, Panagiotis K., Halili, Maria A., Hepburn, Caryn, Nebl, Tom, Supuran, Claudiu T., Nocentini, Alessio, Peat, Thomas S., Poulsen, Sally-Ann
Publicado 2021

Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA

por Petit, Guillaume A., Mohanty, Biswaranjan, McMahon, Róisín M., Nebl, Stefan, Hilko, David H., Wilde, Karyn L., Scanlon, Martin J., Martin, Jennifer L., Halili, Maria A.
Publicado 2022

Comparative Sequence, Structure and Redox Analyses of Klebsiella pneumoniae DsbA Show That Anti-Virulence Target DsbA Enzymes Fall into Distinct Classes

por Kurth, Fabian, Rimmer, Kieran, Premkumar, Lakshmanane, Mohanty, Biswaranjan, Duprez, Wilko, Halili, Maria A., Shouldice, Stephen R., Heras, Begoña, Fairlie, David P., Scanlon, Martin J., Martin, Jennifer L.
Publicado 2013

The suppressor of copper sensitivity protein C from Caulobacter crescentus is a trimeric disulfide isomerase that binds copper(I) with subpicomolar affinity

por Petit, Guillaume A., Hong, Yaoqin, Djoko, Karrera Y., Whitten, Andrew E., Furlong, Emily J., McCoy, Airlie J., Gulbis, Jacqueline M., Totsika, Makrina, Martin, Jennifer L., Halili, Maria A.
Publicado 2022

A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance

por Furlong, Emily J., Lo, Alvin W., Kurth, Fabian, Premkumar, Lakshmanane, Totsika, Makrina, Achard, Maud E. S., Halili, Maria A., Heras, Begoña, Whitten, Andrew E., Choudhury, Hassanul G., Schembri, Mark A., Martin, Jennifer L.
Publicado 2017

Author Correction: A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance

por Furlong, Emily J., Lo, Alvin W., Kurth, Fabian, Premkumar, Lakshmanane, Totsika, Makrina, Achard, Maud E. S., Halili, Maria A., Heras, Begoña, Whitten, Andrew E., Choudhury, Hassanul G., Schembri, Mark A., Martin, Jennifer L.
Publicado 2019

Exploiting a novel conformational switch to control innate immunity mediated by complement protein C3a

por Lohman, Rink-Jan, Hamidon, Johan K., Reid, Robert C., Rowley, Jessica A., Yau, Mei-Kwan, Halili, Maria A., Nielsen, Daniel S., Lim, Junxian, Wu, Kai-Chen, Loh, Zhixuan, Do, Anh, Suen, Jacky Y., Iyer, Abishek, Fairlie, David P.
Publicado 2017