Methods to Make Homogenous Antibody Drug Conjugates

por Kline, Toni, Steiner, Alexander R., Penta, Kalyani, Sato, Aaron K., Hallam, Trevor J., Yin, Gang
Publicado 2014

Development of an E. coli strain for cell‐free ADC manufacturing

por Groff, Dan, Carlos, Nina A., Chen, Rishard, Hanson, Jeffrey A., Liang, Shengwen, Armstrong, Stephanie, Li, Xiaofan, Zhou, Sihong, Steiner, Alex, Hallam, Trevor J., Yin, Gang
Publicado 2021

A simplified and robust protocol for immunoglobulin expression in E scherichia coli cell‐free protein synthesis systems

por Cai, Qi, Hanson, Jeffrey A., Steiner, Alexander R., Tran, Cuong, Masikat, Mary Rose, Chen, Rishard, Zawada, James F., Sato, Aaron K., Hallam, Trevor J., Yin, Gang
Publicado 2015

Targeting CD74 in B-cell non-Hodgkin lymphoma with the antibody-drug conjugate STRO-001

por Li, Xiaofan, Abrahams, Cristina, Yu, Abigail, Embry, Millicent, Henningsen, Robert, DeAlmeida, Venita, Matheny, Shannon, Kline, Toni, Yam, Alice, Stafford, Ryan, Hallam, Trevor, Lupher, Mark, Molina, Arturo
Publicado 2023

Production of bispecific antibodies in “knobs-into-holes” using a cell-free expression system

por Xu, Yiren, Lee, John, Tran, Cuong, Heibeck, Tyler H, Wang, Willie D, Yang, Junhao, Stafford, Ryan L, Steiner, Alexander R, Sato, Aaron K, Hallam, Trevor J, Yin, Gang
Publicado 2014

An Integrated In Vivo/In Vitro Protein Production Platform for Site-Specific Antibody Drug Conjugates

por Hanson, Jeffrey, Groff, Dan, Carlos, Abi, Usman, Hans, Fong, Kevin, Yu, Abigail, Armstrong, Stephanie, Dwyer, Allison, Masikat, Mary Rose, Yuan, Dawei, Tran, Cuong, Heibeck, Tyler, Zawada, James, Chen, Rishard, Hallam, Trevor, Yin, Gang
Publicado 2023

Post-Exposure Protection in Mice against Sudan Virus by a Two Antibody Cocktail

por Froude, Jeffrey W., Herbert, Andrew S., Pelat, Thibaut, Miethe, Sebastian, Zak, Samantha E., Brannan, Jennifer M., Bakken, Russell R., Steiner, Alexander R., Yin, Gang, Hallam, Trevor J., Sato, Aaron K., Hust, Michael, Thullier, Philippe, Dye, John M.
Publicado 2018

Targeting CD74 in multiple myeloma with the novel, site-specific antibody-drug conjugate STRO-001

por Abrahams, Cristina L., Li, Xiaofan, Embry, Millicent, Yu, Abigail, Krimm, Stellanie, Krueger, Sarah, Greenland, Nancy Y., Wen, Kwun Wah, Jones, Chris, DeAlmeida, Venita, Solis, Willy A., Matheny, Shannon, Kline, Toni, Yam, Alice Y., Stafford, Ryan, Wiita, Arun P., Hallam, Trevor, Lupher, Mark, Molina, Arturo
Publicado 2018

In vitro Fab display: a cell-free system for IgG discovery

por Stafford, Ryan L., Matsumoto, Marissa L., Yin, Gang, Cai, Qi, Fung, Juan Jose, Stephenson, Heather, Gill, Avinash, You, Monica, Lin, Shwu-Hwa, Wang, Willie D., Masikat, Mary Rose, Li, Xiaofan, Penta, Kalyani, Steiner, Alex R., Baliga, Ramesh, Murray, Christopher J., Thanos, Christopher D., Hallam, Trevor J., Sato, Aaron K.
Publicado 2014

Discovery of STRO-002, a Novel Homogeneous ADC Targeting Folate Receptor Alpha, for the Treatment of Ovarian and Endometrial Cancers

por Li, Xiaofan, Zhou, Sihong, Abrahams, Cristina L., Krimm, Stellanie, Smith, Jennifer, Bajjuri, Krishna, Stephenson, Heather T., Henningsen, Robert, Hanson, Jeffrey, Heibeck, Tyler H., Calarese, Daniel, Tran, Cuong, Yin, Gang, Stafford, Ryan L., Yam, Alice Y., Kline, Toni, De Almeida, Venita I., Sato, Aaron K., Lupher, Mark, Bedard, Kristin, Hallam, Trevor J.
Publicado 2023

RF1 attenuation enables efficient non-natural amino acid incorporation for production of homogeneous antibody drug conjugates

por Yin, Gang, Stephenson, Heather T., Yang, Junhao, Li, Xiaofan, Armstrong, Stephanie M., Heibeck, Tyler H., Tran, Cuong, Masikat, Mary Rose, Zhou, Sihong, Stafford, Ryan L., Yam, Alice Y., Lee, John, Steiner, Alexander R., Gill, Avinash, Penta, Kalyani, Pollitt, Sonia, Baliga, Ramesh, Murray, Christopher J., Thanos, Christopher D., McEvoy, Leslie M., Sato, Aaron K., Hallam, Trevor J.
Publicado 2017

Egg-Derived Anti-SARS-CoV-2 Immunoglobulin Y (IgY) With Broad Variant Activity as Intranasal Prophylaxis Against COVID-19

por Frumkin, Lyn R., Lucas, Michaela, Scribner, Curtis L., Ortega-Heinly, Nastassja, Rogers, Jayden, Yin, Gang, Hallam, Trevor J., Yam, Alice, Bedard, Kristin, Begley, Rebecca, Cohen, Courtney A., Badger, Catherine V., Abbasi, Shawn A., Dye, John M., McMillan, Brian, Wallach, Michael, Bricker, Traci L., Joshi, Astha, Boon, Adrianus C. M., Pokhrel, Suman, Kraemer, Benjamin R., Lee, Lucia, Kargotich, Stephen, Agochiya, Mahima, John, Tom St., Mochly-Rosen, Daria
Publicado 2022