Manhattan Harvester and Cropper: a system for GWAS peak detection

por Haller, Toomas, Tasa, Tõnis, Metspalu, Andres
Publicado 2019

RegScan: a GWAS tool for quick estimation of allele effects on continuous traits and their combinations

por Haller, Toomas, Kals, Mart, Esko, Tõnu, Mägi, Reedik, Fischer, Krista
Publicado 2015

Advances in Genomic Discovery and Implications for Personalized Prevention and Medicine: Estonia as Example

por Prins, Bram Peter, Leitsalu, Liis, Pärna, Katri, Fischer, Krista, Metspalu, Andres, Haller, Toomas, Snieder, Harold
Publicado 2021

Association analysis of juvenile idiopathic arthritis genetic susceptibility factors in Estonian patients

por Nikopensius, Tiit, Niibo, Priit, Haller, Toomas, Jagomägi, Triin, Voog-Oras, Ülle, Tõnisson, Neeme, Metspalu, Andres, Saag, Mare, Pruunsild, Chris
Publicado 2021

Ancestry deconvolution and partial polygenic score can improve susceptibility predictions in recently admixed individuals

por Marnetto, Davide, Pärna, Katri, Läll, Kristi, Molinaro, Ludovica, Montinaro, Francesco, Haller, Toomas, Metspalu, Mait, Mägi, Reedik, Fischer, Krista, Pagani, Luca
Publicado 2020

Common clinical blood and urine biomarkers for ischemic stroke: an Estonian Electronic Health Records database study

por Kurvits, Siim, Harro, Ainika, Reigo, Anu, Ott, Anne, Laur, Sven, Särg, Dage, Tampuu, Ardi, Alasoo, Kaur, Vilo, Jaak, Milani, Lili, Haller, Toomas
Publicado 2023

MixFit: Methodology for Computing Ancestry-Related Genetic Scores at the Individual Level and Its Application to the Estonian and Finnish Population Studies

por Haller, Toomas, Leitsalu, Liis, Fischer, Krista, Nuotio, Marja-Liisa, Esko, Tõnu, Boomsma, Dorothea Irene, Kyvik, Kirsten Ohm, Spector, Tim D., Perola, Markus, Metspalu, Andres
Publicado 2017

Genetic variation in the Estonian population: pharmacogenomics study of adverse drug effects using electronic health records

por Tasa, Tõnis, Krebs, Kristi, Kals, Mart, Mägi, Reedik, Lauschke, Volker M., Haller, Toomas, Puurand, Tarmo, Remm, Maido, Esko, Tõnu, Metspalu, Andres, Vilo, Jaak, Milani, Lili
Publicado 2018

Lacking mechanistic disease definitions and corresponding association data hamper progress in network medicine and beyond

por Sadegh, Sepideh, Skelton, James, Anastasi, Elisa, Maier, Andreas, Adamowicz, Klaudia, Möller, Anna, Kriege, Nils M., Kronberg, Jaanika, Haller, Toomas, Kacprowski, Tim, Wipat, Anil, Baumbach, Jan, Blumenthal, David B.
Publicado 2023

Metabolites of milk intake: a metabolomic approach in UK twins with findings replicated in two European cohorts

por Pallister, Tess, Haller, Toomas, Thorand, Barbara, Altmaier, Elisabeth, Cassidy, Aedin, Martin, Tiphaine, Jennings, Amy, Mohney, Robert P., Gieger, Christian, MacGregor, Alexander, Kastenmüller, Gabi, Metspalu, Andres, Spector, Tim D., Menni, Cristina
Publicado 2016

Biomarker Profiling by Nuclear Magnetic Resonance Spectroscopy for the Prediction of All-Cause Mortality: An Observational Study of 17,345 Persons

por Fischer, Krista, Kettunen, Johannes, Würtz, Peter, Haller, Toomas, Havulinna, Aki S., Kangas, Antti J., Soininen, Pasi, Esko, Tõnu, Tammesoo, Mari-Liis, Mägi, Reedik, Smit, Steven, Palotie, Aarno, Ripatti, Samuli, Salomaa, Veikko, Ala-Korpela, Mika, Perola, Markus, Metspalu, Andres
Publicado 2014

Untargeted metabolomics profiling in pediatric patients and adult populations indicates a connection between lipid imbalance and epilepsy

por Oja, Kaisa Teele, Ilisson, Mihkel, Reinson, Karit, Muru, Kai, Reimand, Tiia, Peterson, Hedi, Fishman, Dmytro, Esko, Tõnu, Haller, Toomas, Kronberg, Jaanika, Wojcik, Monica H., Kennedy, Adam, Michelotti, Gregory, O’Donnell-Luria, Anne, Õiglane-Šlik, Eve, Pajusalu, Sander, Õunap, Katrin
Publicado 2023

Circulating metabolic biomarkers of renal function in diabetic and non-diabetic populations

por Barrios, Clara, Zierer, Jonas, Würtz, Peter, Haller, Toomas, Metspalu, Andres, Gieger, Christian, Thorand, Barbara, Meisinger, Christa, Waldenberger, Melanie, Raitakari, Olli, Lehtimäki, Terho, Otero, Sol, Rodríguez, Eva, Pedro-Botet, Juan, Kähönen, Mika, Ala-Korpela, Mika, Kastenmüller, Gabi, Spector, Tim D., Pascual, Julio, Menni, Cristina
Publicado 2018

Search for Early Pancreatic Cancer Blood Biomarkers in Five European Prospective Population Biobanks Using Metabolomics

por Fest, Jesse, Vijfhuizen, Lisanne S, Goeman, Jelle J, Veth, Olga, Joensuu, Anni, Perola, Markus, Männistö, Satu, Ness-Jensen, Eivind, Hveem, Kristian, Haller, Toomas, Tonisson, Neeme, Mikkel, Kairit, Metspalu, Andres, van Duijn, Cornelia M, Ikram, Arfan, Stricker, Bruno H, Ruiter, Rikje, van Eijck, Casper H J, van Ommen, Gert-Jan B, ʼt Hoen, Peter A C
Publicado 2019

Rare variant analyses across multiethnic cohorts identify novel genes for refractive error

por Musolf, Anthony M., Haarman, Annechien E. G., Luben, Robert N., Ong, Jue-Sheng, Patasova, Karina, Trapero, Rolando Hernandez, Marsh, Joseph, Jain, Ishika, Jain, Riya, Wang, Paul Zhiping, Lewis, Deyana D., Tedja, Milly S., Iglesias, Adriana I., Li, Hengtong, Cowan, Cameron S., Biino, Ginevra, Klein, Alison P., Duggal, Priya, Mackey, David A., Hayward, Caroline, Haller, Toomas, Metspalu, Andres, Wedenoja, Juho, Pärssinen, Olavi, Cheng, Ching-Yu, Saw, Seang-Mei, Stambolian, Dwight, Hysi, Pirro G., Khawaja, Anthony P., Vitart, Veronique, Hammond, Christopher J., van Duijn, Cornelia M., Verhoeven, Virginie J. M., Klaver, Caroline C. W., Bailey-Wilson, Joan E.
Publicado 2023

The blood metabolome of incident kidney cancer: A case–control study nested within the MetKid consortium

por Guida, Florence, Tan, Vanessa Y., Corbin, Laura J., Smith-Byrne, Karl, Alcala, Karine, Langenberg, Claudia, Stewart, Isobel D., Butterworth, Adam S., Surendran, Praveen, Achaintre, David, Adamski, Jerzy, Amiano, Pilar, Bergmann, Manuela M., Bull, Caroline J., Dahm, Christina C., Gicquiau, Audrey, Giles, Graham G., Gunter, Marc J., Haller, Toomas, Langhammer, Arnulf, Larose, Tricia L., Ljungberg, Börje, Metspalu, Andres, Milne, Roger L., Muller, David C., Nøst, Therese H., Pettersen Sørgjerd, Elin, Prehn, Cornelia, Riboli, Elio, Rinaldi, Sabina, Rothwell, Joseph A., Scalbert, Augustin, Schmidt, Julie A., Severi, Gianluca, Sieri, Sabina, Vermeulen, Roel, Vincent, Emma E., Waldenberger, Melanie, Timpson, Nicholas J., Johansson, Mattias
Publicado 2021

Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium

por van der Spek, Ashley, Broer, Linda, Draisma, Harmen H. M., Pool, René, Albrecht, Eva, Beekman, Marian, Mangino, Massimo, Raag, Mait, Nyholt, Dale R., Dharuri, Harish K., Codd, Veryan, Amin, Najaf, de Geus, Eco J. C., Deelen, Joris, Demirkan, Ayse, Yet, Idil, Fischer, Krista, Haller, Toomas, Henders, Anjali K., Isaacs, Aaron, Medland, Sarah E., Montgomery, Grant W., Mooijaart, Simon P., Strauch, Konstantin, Suchiman, H. Eka D., Vaarhorst, Anika A. M., van Heemst, Diana, Wang-Sattler, Rui, Whitfield, John B., Willemsen, Gonneke, Wright, Margaret J., Martin, Nicholas G., Samani, Nilesh J., Metspalu, Andres, Eline Slagboom, P., Spector, Tim D., Boomsma, Dorret I., van Duijn, Cornelia M., Gieger, Christian
Publicado 2019

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

por Kettunen, Johannes, Demirkan, Ayşe, Würtz, Peter, Draisma, Harmen H.M., Haller, Toomas, Rawal, Rajesh, Vaarhorst, Anika, Kangas, Antti J., Lyytikäinen, Leo-Pekka, Pirinen, Matti, Pool, René, Sarin, Antti-Pekka, Soininen, Pasi, Tukiainen, Taru, Wang, Qin, Tiainen, Mika, Tynkkynen, Tuulia, Amin, Najaf, Zeller, Tanja, Beekman, Marian, Deelen, Joris, van Dijk, Ko Willems, Esko, Tõnu, Hottenga, Jouke-Jan, van Leeuwen, Elisabeth M, Lehtimäki, Terho, Mihailov, Evelin, Rose, Richard J., de Craen, Anton J.M., Gieger, Christian, Kähönen, Mika, Perola, Markus, Blankenberg, Stefan, Savolainen, Markku J., Verhoeven, Aswin, Viikari, Jorma, Willemsen, Gonneke, Boomsma, Dorret I., van Duijn, Cornelia M., Eriksson, Johan, Jula, Antti, Järvelin, Marjo-Riitta, Kaprio, Jaakko, Metspalu, Andres, Raitakari, Olli, Salomaa, Veikko, Slagboom, P. Eline, Waldenberger, Melanie, Ripatti, Samuli, Ala-Korpela, Mika
Publicado 2016

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

por Tedja, Milly S., Wojciechowski, Robert, Hysi, Pirro G., Eriksson, Nicholas, Furlotte, Nicholas A., Verhoeven, Virginie J.M., Iglesias, Adriana I., Meester-Smoor, Magda A., Tompson, Stuart W., Fan, Qiao, Khawaja, Anthony P., Cheng, Ching-Yu, Höhn, René, Yamashiro, Kenji, Wenocur, Adam, Grazal, Clare, Haller, Toomas, Metspalu, Andres, Wedenoja, Juho, Jonas, Jost B., Wang, Ya Xing, Xie, Jing, Mitchell, Paul, Foster, Paul J., Klein, Barbara E.K., Klein, Ronald, Paterson, Andrew D., Hosseini, S. Mohsen, Shah, Rupal L., Williams, Cathy, Teo, Yik Ying, Tham, Yih Chung, Gupta, Preeti, Zhao, Wanting, Shi, Yuan, Saw, Woei-Yuh, Tai, E-Shyong, Sim, Xue Ling, Huffman, Jennifer E., Polašek, Ozren, Hayward, Caroline, Bencic, Goran, Rudan, Igor, Wilson, James F., Joshi, Peter K., Tsujikawa, Akitaka, Matsuda, Fumihiko, Whisenhunt, Kristina N., Zeller, Tanja, van der Spek, Peter J., Haak, Roxanna, Meijers-Heijboer, Hanne, van Leeuwen, Elisabeth M., Iyengar, Sudha K., Lass, Jonathan H., Hofman, Albert, Rivadeneira, Fernando, Uitterlinden, André G., Vingerling, Johannes R., Lehtimäki, Terho, Raitakari, Olli T., Biino, Ginevra, Concas, Maria Pina, Schwantes-An, Tae-Hwi, Igo, Robert P., Cuellar-Partida, Gabriel, Martin, Nicholas G., Craig, Jamie E., Gharahkhani, Puya, Williams, Katie M., Nag, Abhishek, Rahi, Jugnoo S., Cumberland, Phillippa M., Delcourt, Cécile, Bellenguez, Céline, Ried, Janina S., Bergen, Arthur A., Meitinger, Thomas, Gieger, Christian, Wong, Tien Yin, Hewitt, Alex W., Mackey, David A., Simpson, Claire L., Pfeiffer, Norbert, Pärssinen, Olavi, Baird, Paul N., Vitart, Veronique, Amin, Najaf, van Duijn, Cornelia M., Bailey-Wilson, Joan E., Young, Terri L., Saw, Seang-Mei, Stambolian, Dwight, MacGregor, Stuart, Guggenheim, Jeremy A., Tung, Joyce Y., Hammond, Christopher J., Klaver, Caroline C.W.
Publicado 2018

Modulation of Genetic Associations with Serum Urate Levels by Body-Mass-Index in Humans

por Huffman, Jennifer E., Albrecht, Eva, Teumer, Alexander, Mangino, Massimo, Kapur, Karen, Johnson, Toby, Kutalik, Zoltán, Pirastu, Nicola, Pistis, Giorgio, Lopez, Lorna M., Haller, Toomas, Salo, Perttu, Goel, Anuj, Li, Man, Tanaka, Toshiko, Dehghan, Abbas, Ruggiero, Daniela, Malerba, Giovanni, Smith, Albert V., Nolte, Ilja M., Portas, Laura, Phipps-Green, Amanda, Boteva, Lora, Navarro, Pau, Johansson, Asa, Hicks, Andrew A., Polasek, Ozren, Esko, Tõnu, Peden, John F., Harris, Sarah E., Murgia, Federico, Wild, Sarah H., Tenesa, Albert, Tin, Adrienne, Mihailov, Evelin, Grotevendt, Anne, Gislason, Gauti K., Coresh, Josef, D'Adamo, Pio, Ulivi, Sheila, Vollenweider, Peter, Waeber, Gerard, Campbell, Susan, Kolcic, Ivana, Fisher, Krista, Viigimaa, Margus, Metter, Jeffrey E., Masciullo, Corrado, Trabetti, Elisabetta, Bombieri, Cristina, Sorice, Rossella, Döring, Angela, Reischl, Eva, Strauch, Konstantin, Hofman, Albert, Uitterlinden, Andre G., Waldenberger, Melanie, Wichmann, H-Erich, Davies, Gail, Gow, Alan J., Dalbeth, Nicola, Stamp, Lisa, Smit, Johannes H., Kirin, Mirna, Nagaraja, Ramaiah, Nauck, Matthias, Schurmann, Claudia, Budde, Kathrin, Farrington, Susan M., Theodoratou, Evropi, Jula, Antti, Salomaa, Veikko, Sala, Cinzia, Hengstenberg, Christian, Burnier, Michel, Mägi, Reedik, Klopp, Norman, Kloiber, Stefan, Schipf, Sabine, Ripatti, Samuli, Cabras, Stefano, Soranzo, Nicole, Homuth, Georg, Nutile, Teresa, Munroe, Patricia B., Hastie, Nicholas, Campbell, Harry, Rudan, Igor, Cabrera, Claudia, Haley, Chris, Franco, Oscar H., Merriman, Tony R., Gudnason, Vilmundur, Pirastu, Mario, Penninx, Brenda W., Snieder, Harold, Metspalu, Andres, Ciullo, Marina, Pramstaller, Peter P., van Duijn, Cornelia M., Ferrucci, Luigi, Gambaro, Giovanni, Deary, Ian J., Dunlop, Malcolm G., Wilson, James F., Gasparini, Paolo, Gyllensten, Ulf, Spector, Tim D., Wright, Alan F., Hayward, Caroline, Watkins, Hugh, Perola, Markus, Bochud, Murielle, Kao, W. H. Linda, Caulfield, Mark, Toniolo, Daniela, Völzke, Henry, Gieger, Christian, Köttgen, Anna, Vitart, Veronique
Publicado 2015