New Insights into Alzheimer's Disease Progression: A Combined TMS and Structural MRI Study

por Niskanen, Eini, Könönen, Mervi, Määttä, Sara, Hallikainen, Merja, Kivipelto, Miia, Casarotto, Silvia, Massimini, Marcello, Vanninen, Ritva, Mervaala, Esa, Karhu, Jari, Soininen, Hilkka
Publicado 2011

Tolerability of ORM-12741 and effects on episodic memory in patients with Alzheimer's disease

por Rinne, Juha O., Wesnes, Keith, Cummings, Jeffrey L., Hakulinen, Pasi, Hallikainen, Merja, Hänninen, Jutta, Murphy, Michael, Riordan, Henry, Scheinin, Mika, Soininen, Hilkka, Rouru, Juha
Publicado 2016

Obesity and Brain Vulnerability in Normal and Abnormal Aging: A Multimodal MRI Study

por Dake, Manmohi D., De Marco, Matteo, Blackburn, Daniel J., Wilkinson, Iain D., Remes, Anne, Liu, Yawu, Pikkarainen, Maria, Hallikainen, Merja, Soininen, Hilkka, Venneri, Annalena
Publicado 2021

Shortening of Saccades as a Possible Easy-to-Use Biomarker to Detect Risk of Alzheimer’s Disease

por Hannonen, Sanna, Andberg, Sami, Kärkkäinen, Virve, Rusanen, Minna, Lehtola, Juha-Matti, Saari, Toni, Korhonen, Ville, Hokkanen, Laura, Hallikainen, Merja, Hänninen, Tuomo, Leinonen, Ville, Kaarniranta, Kai, Bednarik, Roman, Koivisto, Anne M.
Publicado 2022

Computer-based Eye-tracking Analysis of King-Devick Test Differentiates Persons With Idiopathic Normal Pressure Hydrocephalus From Cognitively Unimpaired

por Lehtola, Juha-Matti, Kärkkäinen, Virve, Andberg, Sami, Hannonen, Sanna, Rusanen, Minna, Saari, Toni, Korhonen, Ville, Hokkanen, Laura, Hallikainen, Merja, Hänninen, Tuomo, Kaarniranta, Kai, Bednarik, Roman, Leinonen, Ville, Koivisto, Anne M.
Publicado 2022

Safety, tolerability and efficacy of the glutaminyl cyclase inhibitor PQ912 in Alzheimer’s disease: results of a randomized, double-blind, placebo-controlled phase 2a study

por Scheltens, Philip, Hallikainen, Merja, Grimmer, Timo, Duning, Thomas, Gouw, Alida A, Teunissen, Charlotte E, Wink, Alle Meije, Maruff, Paul, Harrison, John, van Baal, Caroline M, Bruins, Suzanne, Lues, Inge, Prins, Niels D
Publicado 2018

Third follow-up of the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) cohort investigating determinants of cognitive, physical, and psychosocial wellbeing among the oldest...

por Barbera, Mariagnese, Kulmala, Jenni, Lisko, Inna, Pietilä, Eija, Rosenberg, Anna, Hallikainen, Ilona, Hallikainen, Merja, Laatikainen, Tiina, Lehtisalo, Jenni, Neuvonen, Elisa, Rusanen, Minna, Soininen, Hilkka, Tuomilehto, Jaakko, Ngandu, Tiia, Solomon, Alina, Kivipelto, Miia
Publicado 2020

Using the Disease State Fingerprint Tool for Differential Diagnosis of Frontotemporal Dementia and Alzheimer's Disease

por Muñoz-Ruiz, Miguel Ángel, Hall, Anette, Mattila, Jussi, Koikkalainen, Juha, Herukka, Sanna-Kaisa, Husso, Minna, Hänninen, Tuomo, Vanninen, Ritva, Liu, Yawu, Hallikainen, Merja, Lötjönen, Jyrki, Remes, Anne M., Alafuzoff, Irina, Soininen, Hilkka, Hartikainen, Päivi
Publicado 2016

Metabolic Profiles Help Discriminate Mild Cognitive Impairment from Dementia Stage in Alzheimer’s Disease

por Jääskeläinen, Olli, Hall, Anette, Tiainen, Mika, van Gils, Mark, Lötjönen, Jyrki, Kangas, Antti J., Helisalmi, Seppo, Pikkarainen, Maria, Hallikainen, Merja, Koivisto, Anne, Hartikainen, Päivi, Hiltunen, Mikko, Ala-Korpela, Mika, Soininen, Pasi, Soininen, Hilkka, Herukka, Sanna-Kaisa
Publicado 2020

The influence of insulin resistance on cerebrospinal fluid and plasma biomarkers of Alzheimer’s pathology

por Westwood, Sarah, Liu, Benjamine, Baird, Alison L., Anand, Sneha, Nevado-Holgado, Alejo J., Newby, Danielle, Pikkarainen, Maria, Hallikainen, Merja, Kuusisto, Johanna, Streffer, Johannes R., Novak, Gerald, Blennow, Kaj, Andreasson, Ulf, Zetterberg, Henrik, Smith, Ulf, Laakso, Markku, Soininen, Hilkka, Lovestone, Simon
Publicado 2017

A FinnGen pilot clinical recall study for Alzheimer’s disease

por Julkunen, Valtteri, Schwarz, Claudia, Kalapudas, Juho, Hallikainen, Merja, Piironen, Aino-Kaisa, Mannermaa, Arto, Kujala, Hanna, Laitinen, Timo, Kosma, Veli-Matti, Paajanen, Teemu I., Kälviäinen, Reetta, Hiltunen, Mikko, Herukka, Sanna-Kaisa, Kärkkäinen, Sari, Kokkola, Tarja, Urjansson, Mia, Perola, Markus, Palotie, Aarno, Vuoksimaa, Eero, Runz, Heiko
Publicado 2023

Gait Disturbances are Associated with Increased Cognitive Impairment and Cerebrospinal Fluid Tau Levels in a Memory Clinic Cohort

por Muurling, Marijn, Rhodius-Meester, Hanneke F.M., Pärkkä, Juha, van Gils, Mark, Frederiksen, Kristian S., Bruun, Marie, Hasselbalch, Steen G., Soininen, Hilkka, Herukka, Sanna-Kaisa, Hallikainen, Merja, Teunissen, Charlotte E., Visser, Pieter Jelle, Scheltens, Philip, van der Flier, Wiesje M., Mattila, Jussi, Lötjönen, Jyrki, de Boer, Casper
Publicado 2020

Impact of a clinical decision support tool on prediction of progression in early-stage dementia: a prospective validation study

por Bruun, Marie, Frederiksen, Kristian S., Rhodius-Meester, Hanneke F. M., Baroni, Marta, Gjerum, Le, Koikkalainen, Juha, Urhemaa, Timo, Tolonen, Antti, van Gils, Mark, Rueckert, Daniel, Dyremose, Nadia, Andersen, Birgitte B., Lemstra, Afina W., Hallikainen, Merja, Kurl, Sudhir, Herukka, Sanna-Kaisa, Remes, Anne M., Waldemar, Gunhild, Soininen, Hilkka, Mecocci, Patrizia, van der Flier, Wiesje M., Lötjönen, Jyrki, Hasselbalch, Steen G.
Publicado 2019

Effects of age, amyloid, sex, and APOE ε4 on the CSF proteome in normal cognition

por Wesenhagen, Kirsten E.J., Gobom, Johan, Bos, Isabelle, Vos, Stephanie J.B., Martinez‐Lage, Pablo, Popp, Julius, Tsolaki, Magda, Vandenberghe, Rik, Freund‐Levi, Yvonne, Verhey, Frans, Lovestone, Simon, Streffer, Johannes, Dobricic, Valerija, Bertram, Lars, Blennow, Kaj, Pikkarainen, Maria, Hallikainen, Merja, Kuusisto, Johanna, Laakso, Markku, Soininen, Hilkka, Scheltens, Philip, Zetterberg, Henrik, Teunissen, Charlotte E., Visser, Pieter Jelle, Tijms, Betty M.
Publicado 2022