Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, β-arrestin 2, PDE4D3 complex

por Halls, Michelle L, Cooper, Dermot M F
Publicado 2010

Editorial: Recent Advances in G Protein-Coupled Receptor Signalling: Impact of Intracellular Location, Environment and Biased Agonism

por Halls, Michelle L., Davenport, Anthony P., Summers, Roger J.
Publicado 2021

GRK Mediates μ-Opioid Receptor Plasma Membrane Reorganization

por Gondin, Arisbel B., Halls, Michelle L., Canals, Meritxell, Briddon, Stephen J.
Publicado 2019

Muscarinic receptors stimulate AC2 by novel phosphorylation sites, whereas Gβγ subunits exert opposing effects depending on the G-protein source

por Shen, Jia X., Wachten, Sebastian, Halls, Michelle L., Everett, Katy L., Cooper, Dermot M. F.
Publicado 2012

AKAP79/150 Interacts with AC8 and Regulates Ca(2+)-dependent cAMP Synthesis in Pancreatic and Neuronal Systems

por Willoughby, Debbie, Masada, Nanako, Wachten, Sebastian, Pagano, Mario, Halls, Michelle L., Everett, Katy L., Ciruela, Antonio, Cooper, Dermot M. F.
Publicado 2010

Inhibition of the Proliferation of Human Lung Fibroblasts by Prostacyclin Receptor Agonists is Linked to a Sustained cAMP Signal in the Nucleus

por Roberts, Maxine J., May, Lauren T., Keen, Alastair C., Liu, Bonan, Lam, Terrance, Charlton, Steven J., Rosethorne, Elizabeth M., Halls, Michelle L.
Publicado 2021

Ligand-dependent spatiotemporal signaling profiles of the μ-opioid receptor are controlled by distinct protein-interaction networks

por Civciristov, Srgjan, Huang, Cheng, Liu, Bonan, Marquez, Elsa A., Gondin, Arisbel B., Schittenhelm, Ralf B., Ellisdon, Andrew M., Canals, Meritxell, Halls, Michelle L.
Publicado 2019

Structure of the metastatic factor P-Rex1 reveals a two-layered autoinhibitory mechanism

por Chang, Yong-Gang, Lupton, Christopher J., Bayly-Jones, Charles, Keen, Alastair C., D’Andrea, Laura, Lucato, Christina M., Steele, Joel R., Venugopal, Hari, Schittenhelm, Ralf B., Whisstock, James C., Halls, Michelle L., Ellisdon, Andrew M.
Publicado 2022

β2-adrenoceptor signaling regulates invadopodia formation to enhance tumor cell invasion

por Creed, Sarah J., Le, Caroline P., Hassan, Mona, Pon, Cindy K., Albold, Sabine, Chan, Keefe T., Berginski, Matthew E., Huang, Zhendong, Bear, James E., Lane, J. Robert, Halls, Michelle L., Ferrari, Davide, Nowell, Cameron J., Sloan, Erica K.
Publicado 2015

A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes

por Mai, Quynh N., Shenoy, Priyank, Quach, Tim, Retamal, Jeffri S., Gondin, Arisbel B., Yeatman, Holly R., Aurelio, Luigi, Conner, Joshua W., Poole, Daniel P., Canals, Meritxell, Nowell, Cameron J., Graham, Bim, Davis, Thomas P., Briddon, Stephen J., Hill, Stephen J., Porter, Christopher J.H., Bunnett, Nigel W., Halls, Michelle L., Veldhuis, Nicholas A.
Publicado 2021

Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy

por To, Eunice E., Vlahos, Ross, Luong, Raymond, Halls, Michelle L., Reading, Patrick C., King, Paul T., Chan, Christopher, Drummond, Grant R., Sobey, Christopher G., Broughton, Brad R. S., Starkey, Malcolm R., van der Sluis, Renee, Lewin, Sharon R., Bozinovski, Steven, O’Neill, Luke A. J., Quach, Tim, Porter, Christopher J. H., Brooks, Doug A., O’Leary, John J., Selemidis, Stavros
Publicado 2017