Histone deacetylase inhibitors for cancer therapy: An evolutionarily ancient resistance response may explain their limited success

por Halsall, John A., Turner, Bryan M.
Publicado 2016

Immunolabelling of human metaphase chromosomes reveals the same banded distribution of histone H3 isoforms methylated at lysine 4 in primary lymphocytes and cultured cell lines

por Terrenoire, Edith, Halsall, John A, Turner, Bryan M
Publicado 2015

Cells adapt to the epigenomic disruption caused by histone deacetylase inhibitors through a coordinated, chromatin-mediated transcriptional response

por Halsall, John A, Turan, Nil, Wiersma, Maaike, Turner, Bryan M
Publicado 2015

A long intergenic non-coding RNA regulates nuclear localization of DNA methyl transferase-1

por Jones, Rhian, Wijesinghe, Susanne, Wilson, Claire, Halsall, John, Liloglou, Triantafillos, Kanhere, Aditi
Publicado 2021

Genes Are Often Sheltered from the Global Histone Hyperacetylation Induced by HDAC Inhibitors

por Halsall, John, Gupta, Vibhor, O'Neill, Laura P., Turner, Bryan M., Nightingale, Karl P.
Publicado 2012

Protein kinase Msk1 physically and functionally interacts with the KMT2A/MLL1 methyltransferase complex and contributes to the regulation of multiple target genes

por Wiersma, Maaike, Bussiere, Marianne, Halsall, John A., Turan, Nil, Slany, Robert, Turner, Bryan M., Nightingale, Karl P.
Publicado 2016

Histone modifications form a cell-type-specific chromosomal bar code that persists through the cell cycle

por Halsall, John A., Andrews, Simon, Krueger, Felix, Rutledge, Charlotte E., Ficz, Gabriella, Reik, Wolf, Turner, Bryan M.
Publicado 2021

A novel form of JARID2 is required for differentiation in lineage‐committed cells

por Al‐Raawi, Diaa, Jones, Rhian, Wijesinghe, Susanne, Halsall, John, Petric, Marija, Roberts, Sally, Hotchin, Neil A, Kanhere, Aditi
Publicado 2018

Morphine leads to global genome changes in H3K27me3 levels via a Polycomb Repressive Complex 2 (PRC2) self-regulatory mechanism in mESCs

por Muñoa-Hoyos, Iraia, Halsall, John A., Araolaza, Manu, Ward, Carl, Garcia, Idoia, Urizar-Arenaza, Itziar, Gianzo, Marta, Garcia, Paloma, Turner, Bryan, Subirán, Nerea
Publicado 2020

The histone deacetylase inhibitor sodium valproate causes limited transcriptional change in mouse embryonic stem cells but selectively overrides Polycomb-mediated Hoxb silencing

por Boudadi, Elsa, Stower, Hannah, Halsall, John A, Rutledge, Charlotte E, Leeb, Martin, Wutz, Anton, O’Neill, Laura P, Nightingale, Karl P, Turner, Bryan M
Publicado 2013

Immunostaining of modified histones defines high-level features of the human metaphase epigenome

por Terrenoire, Edith, McRonald, Fiona, Halsall, John A, Page, Paula, Illingworth, Robert S, Taylor, A Malcolm R, Davison, Val, O'Neill, Laura P, Turner, Bryan M
Publicado 2010