An Activating Mutation Reveals a Second Binding Mode of the Integrin α2 I Domain to the GFOGER Motif in Collagens

por Carafoli, Federico, Hamaia, Samir W., Bihan, Dominique, Hohenester, Erhard, Farndale, Richard W.
Publicado 2013

Tunable bioactivity and mechanics of collagen-based tissue engineering constructs: A comparison of EDC-NHS, genipin and TG2 crosslinkers

por Nair, Malavika, Johal, Ramneek K., Hamaia, Samir W., Best, Serena M., Cameron, Ruth E.
Publicado 2020

Selectivity of the collagen-binding integrin inhibitors, TC-I-15 and obtustatin

por Hunter, Emma J., Hamaia, Samir W., Gullberg, Donald, Malcor, Jean-Daniel, Farndale, Richard W.
Publicado 2021

Can the SARS-CoV-2 Spike Protein Bind Integrins Independent of the RGD Sequence?

por Beaudoin, Christopher A., Hamaia, Samir W., Huang, Christopher L.-H., Blundell, Tom L., Jackson, Antony P.
Publicado 2021

The effects of inhibition and siRNA knockdown of collagen-binding integrins on human umbilical vein endothelial cell migration and tube formation

por Hunter, Emma J., Hamaia, Samir W., Kim, Peter S.-K., Malcor, Jean-Daniel M., Farndale, Richard W.
Publicado 2022

Mapping of Potent and Specific Binding Motifs, GLOGEN and GVOGEA, for Integrin α1β1 Using Collagen Toolkits II and III

por Hamaia, Samir W., Pugh, Nicholas, Raynal, Nicolas, Némoz, Benjamin, Stone, Rachael, Gullberg, Donald, Bihan, Dominique, Farndale, Richard W.
Publicado 2012

Unique charge-dependent constraint on collagen recognition by integrin α10β1

por Hamaia, Samir W., Luff, Daisy, Hunter, Emma J., Malcor, Jean-Daniel, Bihan, Dominique, Gullberg, Donald, Farndale, Richard W.
Publicado 2017

MMP‐13 binds to platelet receptors αIIbβ3 and GPVI and impairs aggregation and thrombus formation

por Howes, Joanna‐Marie, Pugh, Nicholas, Hamaia, Samir W., Jung, Stephanie M., Knäuper, Vera, Malcor, Jean‐Daniel, Farndale, Richard W.
Publicado 2018

Identification of HSP47 Binding Site on Native Collagen and Its Implications for the Development of HSP47 Inhibitors

por Cai, Haiyan, Sasikumar, Parvathy, Little, Gemma, Bihan, Dominique, Hamaia, Samir W., Zhou, Aiwu, Gibbins, Jonathan M., Farndale, Richard W.
Publicado 2021

Measurement of the Interaction Between Recombinant I-domain from Integrin alpha 2 beta 1 and a Triple Helical Collagen Peptide with the GFOGER Binding Motif Using Molecular Force S...

por Attwood, Simon J., Simpson, Anna M. C., Hamaia, SamirW., Bihan, Dominique, Roy, Debdulal, Farndale, RichardW., Welland, Mark E.
Publicado 2013

Optimisation of UV irradiation as a binding site conserving method for crosslinking collagen-based scaffolds

por Davidenko, Natalia, Bax, Daniel V., Schuster, Carlos F., Farndale, Richard W., Hamaia, Samir W., Best, Serena M., Cameron, Ruth E.
Publicado 2015

Identification of the cis-molecular neighbours of the immune checkpoint protein B7-H4 in the breast cancer cell-line SK-BR-3 by proteomic proximity labelling

por Rees, Johanna S., Cheung, Lawrence C.C., Hamaia, Samir W., Davies, Gareth, Sandercock, Alan, Lilley, Kathryn S., Tigue, Natalie, Jackson, Antony P.
Publicado 2020

The Recognition of Collagen and Triple-helical Toolkit Peptides by MMP-13: SEQUENCE SPECIFICITY FOR BINDING AND CLEAVAGE

por Howes, Joanna-Marie, Bihan, Dominique, Slatter, David A., Hamaia, Samir W., Packman, Len C., Knauper, Vera, Visse, Robert, Farndale, Richard W.
Publicado 2014

The synthesis and coupling of photoreactive collagen-based peptides to restore integrin reactivity to an inert substrate, chemically-crosslinked collagen

por Malcor, Jean-Daniel, Bax, Daniel, Hamaia, Samir W., Davidenko, Natalia, Best, Serena M., Cameron, Ruth E., Farndale, Richard W., Bihan, Dominique
Publicado 2016

A Simple Bioconjugate Attachment Protocol for Use in Single Molecule Force Spectroscopy Experiments Based on Mixed Self-Assembled Monolayers

por Attwood, Simon J., Simpson, Anna M. C., Stone, Rachael, Hamaia, SamirW., Roy, Debdulal, Farndale, RichardW., Ouberai, Myriam, Welland, Mark E.
Publicado 2012

In silico analysis of mutations near S1/S2 cleavage site in SARS‐CoV‐2 spike protein reveals increased propensity of glycosylation in Omicron strain

por Beaudoin, Christopher A., Pandurangan, Arun P., Kim, So Yeon, Hamaia, Samir W., Huang, Christopher L.‐H., Blundell, Tom L., Vedithi, Sundeep Chaitanya, Jackson, Antony P.
Publicado 2022

Chain Alignment of Collagen I Deciphered using Computationally Designed Heterotrimers

por Jalan, Abhishek A., Sammon, Douglas, Hartgerink, Jeffrey D., Brear, Paul, Stott, Katherine, Hamaia, Samir W., Hunter, Emma J., Walker, Douglas R., Leitinger, Birgit, Farndale, Richard W.
Publicado 2020

New Insights into the DT40 B Cell Receptor Cluster Using a Proteomic Proximity Labeling Assay

por Li, Xue-Wen, Rees, Johanna S., Xue, Peng, Zhang, Hong, Hamaia, Samir W., Sanderson, Bailey, Funk, Phillip E., Farndale, Richard W., Lilley, Kathryn S., Perrett, Sarah, Jackson, Antony P.
Publicado 2014

SARS-CoV-2 Omicron subvariant spike N405 unlikely to rapidly deamidate

por Beaudoin, Christopher A., Petsolari, Emmanouela, Hamaia, Samir W., Hala, Sharif, Alofi, Fadwa S., Pandurangan, Arun P., Blundell, Tom L., Chaitanya Vedithi, Sundeep, Huang, Christopher L.-H., Jackson, Antony P.
Publicado 2023

Multimerin 1 supports platelet function in vivo and binds to specific GPAGPOGPX motifs in fibrillar collagens that enhance platelet adhesion

por Leatherdale, Alexander, Parker, D’Andra, Tasneem, Subia, Wang, Yiming, Bihan, Dominique, Bonna, Arkadiusz, Hamaia, Samir W., Gross, Peter L., Ni, Heyu, Doble, Bradley W., Lillicrap, David, Farndale, Richard W., Hayward, Catherine P. M.
Publicado 2020