Expedient access to saturated nitrogen heterocycles by photoredox cyclization of imino-tethered dihydropyridines

por Bissonnette, Noah B., Ellis, J. Michael, Hamann, Lawrence G., Romanov-Michailidis, Fedor
Publicado 2019

Potency, selectivity and prolonged binding of saxagliptin to DPP4: maintenance of DPP4 inhibition by saxagliptin in vitro and ex vivo when compared to a rapidly-dissociating DPP4 i...

por Wang, Aiying, Dorso, Charles, Kopcho, Lisa, Locke, Gregory, Langish, Robert, Harstad, Eric, Shipkova, Petia, Marcinkeviciene, Jovita, Hamann, Lawrence, Kirby, Mark S
Publicado 2012

Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect

por Gao, Min, Nettles, Richard E., Belema, Makonen, Snyder, Lawrence B., Nguyen, Van N., Fridell, Robert A., Serrano-Wu, Michael H., Langley, David R., Sun, Jin-Hua, O’Boyle II, Donald R., Lemm, Julie A., Wang, Chunfu, Knipe, Jay O., Chien, Caly, Colonno, Richard J., Grasela, Dennis M., Meanwell, Nicholas A., Hamann, Lawrence G.
Publicado 2010

Small molecule allosteric inhibitors of RORγt block Th17-dependent inflammation and associated gene expression in vivo

por Saenz, Steven A., Local, Andrea, Carr, Tiffany, Shakya, Arvind, Koul, Shivsmriti, Hu, Haiqing, Chourb, Lisa, Stedman, Justin, Malley, Jenna, D’Agostino, Laura Akullian, Shanmugasundaram, Veerabahu, Malona, John, Schwartz, C. Eric, Beebe, Lisa, Clements, Meghan, Rajaraman, Ganesh, Cho, John, Jiang, Lan, Dubrovskiy, Alex, Kreilein, Matt, Shimanovich, Roman, Hamann, Lawrence G., Escoubet, Laure, Ellis, J. Michael
Publicado 2021