Validation of clinical‐grade whole genome sequencing reproduces cytogenetic analysis and identifies mutational landscape in newly‐diagnosed multiple myeloma patients: A pilot study...

por Lomas, Oliver C., Gooding, Sarah, Cabes, Maite, Dreau, Helene, Wilson, Edward, Polzella, Paolo, Ramasamy, Karthik, Hamblin, Angela D.
Publicado 2021

PB2000: A COMPREHENSIVE NGS PANEL APPROACH FOR CLINICAL GENOMIC ANALYSIS IN HAEMATOLOGICAL MALIGNANCY

por Mason, Joanne, Skowronska, Anna, Barrows, Natalie, Hill, David, Page, Paula, Hamblin, Angela, Clokie, Sam, Feber, Andrew, Hastings, Robert, Cross, Nicholas
Publicado 2023

Rapid Emergence of Chronic Lymphocytic Leukemia During JAK2 Inhibitor Therapy in a Patient With Myelofibrosis

por Sousos, Nikolaos, Buck, Gemma, Rodriguez-Meira, Alba, Norfo, Ruggiero, Hamblin, Angela, Pezzella, Francesco, Davies, Jennifer, Hublitz, Philip, Psaila, Bethan, Mead, Adam J.
Publicado 2020

The burden of invasive infections in neutropenic patients: incidence, outcomes, and use of granulocyte transfusions

por Netelenbos, Tanja, Massey, Edwin, de Wreede, Liesbeth C., Harding, Kay, Hamblin, Angela, Sekhar, Mallika, Li, Anna, Ypma, Paula F., Ball, Lynn, Zwaginga, Jaap Jan, Stanworth, Simon J.
Publicado 2018

In utero origin of myelofibrosis presenting in adult monozygotic twins

por Sousos, Nikolaos, Ní Leathlobhair, Máire, Simoglou Karali, Christina, Louka, Eleni, Bienz, Nicola, Royston, Daniel, Clark, Sally-Ann, Hamblin, Angela, Howard, Kieran, Mathews, Vikram, George, Biju, Roy, Anindita, Psaila, Bethan, Wedge, David C., Mead, Adam J.
Publicado 2022

Clinical applicability and cost of a 46-gene panel for genomic analysis of solid tumours: Retrospective validation and prospective audit in the UK National Health Service

por Hamblin, Angela, Wordsworth, Sarah, Fermont, Jilles M., Page, Suzanne, Kaur, Kulvinder, Camps, Carme, Kaisaki, Pamela, Gupta, Avinash, Talbot, Denis, Middleton, Mark, Henderson, Shirley, Cutts, Anthony, Vavoulis, Dimitrios V., Housby, Nick, Tomlinson, Ian, Taylor, Jenny C., Schuh, Anna
Publicado 2017

Unravelling Intratumoral Heterogeneity through High-Sensitivity Single-Cell Mutational Analysis and Parallel RNA Sequencing

por Rodriguez-Meira, Alba, Buck, Gemma, Clark, Sally-Ann, Povinelli, Benjamin J., Alcolea, Veronica, Louka, Eleni, McGowan, Simon, Hamblin, Angela, Sousos, Nikolaos, Barkas, Nikolaos, Giustacchini, Alice, Psaila, Bethan, Jacobsen, Sten Eirik W., Thongjuea, Supat, Mead, Adam J.
Publicado 2019

Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia

por Louka, Eleni, Povinelli, Benjamin, Rodriguez-Meira, Alba, Buck, Gemma, Wen, Wei Xiong, Wang, Guanlin, Sousos, Nikolaos, Ashley, Neil, Hamblin, Angela, Booth, Christopher A.G., Roy, Anindita, Elliott, Natalina, Iskander, Deena, de la Fuente, Josu, Fordham, Nicholas, O’Byrne, Sorcha, Inglott, Sarah, Norfo, Ruggiero, Salio, Mariolina, Thongjuea, Supat, Rao, Anupama, Roberts, Irene, Mead, Adam J.
Publicado 2021

Clinically actionable mutation profiles in patients with cancer identified by whole-genome sequencing

por Schuh, Anna, Dreau, Helene, Knight, Samantha J.L., Ridout, Kate, Mizani, Tuba, Vavoulis, Dimitris, Colling, Richard, Antoniou, Pavlos, Kvikstad, Erika M., Pentony, Melissa M., Hamblin, Angela, Protheroe, Andrew, Parton, Marina, Shah, Ketan A., Orosz, Zsolt, Athanasou, Nick, Hassan, Bass, Flanagan, Adrienne M., Ahmed, Ahmed, Winter, Stuart, Harris, Adrian, Tomlinson, Ian, Popitsch, Niko, Church, David, Taylor, Jenny C.
Publicado 2018

Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution

por Rodriguez-Meira, Alba, Norfo, Ruggiero, Wen, Sean, Chédeville, Agathe L., Rahman, Haseeb, O’Sullivan, Jennifer, Wang, Guanlin, Louka, Eleni, Kretzschmar, Warren W., Paterson, Aimee, Brierley, Charlotte, Martin, Jean-Edouard, Demeule, Caroline, Bashton, Matthew, Sousos, Nikolaos, Moralli, Daniela, Subha Meem, Lamia, Carrelha, Joana, Wu, Bishan, Hamblin, Angela, Guermouche, Helene, Pasquier, Florence, Marzac, Christophe, Girodon, François, Vainchenker, William, Drummond, Mark, Harrison, Claire, Chapman, J. Ross, Plo, Isabelle, Jacobsen, Sten Eirik W., Psaila, Bethan, Thongjuea, Supat, Antony-Debré, Iléana, Mead, Adam J.
Publicado 2023

Use of whole genome sequencing to determine genetic basis of suspected mitochondrial disorders: cohort study

por Schon, Katherine R, Horvath, Rita, Wei, Wei, Calabrese, Claudia, Tucci, Arianna, Ibañez, Kristina, Ratnaike, Thiloka, Pitceathly, Robert D S, Bugiardini, Enrico, Quinlivan, Rosaline, Hanna, Michael G, Clement, Emma, Ashton, Emma, Sayer, John A, Brennan, Paul, Josifova, Dragana, Izatt, Louise, Fratter, Carl, Nesbitt, Victoria, Barrett, Timothy, McMullen, Dominic J, Smith, Audrey, Deshpande, Charulata, Smithson, Sarah F, Festenstein, Richard, Canham, Natalie, Caulfield, Mark, Houlden, Henry, Rahman(, Shamima, Chinnery, Patrick F, Ambrose, John C, Arumugam, Prabhu, Bevers, Roel, Bleda, Marta, Boardman-Pretty, Freya, Boustred, Christopher R, Brittain, Helen, Caulfield, Mark J, Chan, Georgia C, Elgar, Greg, Fowler, Tom, Giess, Adam, Hamblin, Angela, Henderson, Shirley, Hubbard, Tim J P, Jackson, Rob, Jones, Louise J, Kasperaviciute, Dalia, Kayikci, Melis, Kousathanas, Athanasios, Lahnstein, Lea, Leigh, Sarah E A, Leong, Ivonne U S, Lopez, Javier F, Maleady-Crowe, Fiona, McEntegart, Meriel, Minneci, Federico, Moutsianas, Loukas, Mueller, Michael, Murugaesu, Nirupa, Need, Anna C, O’Donovan, Peter, Odhams, Chris A, Patch, Christine, Buonerimo Pereira, Mariana, Perez-Gil, Daniel, Pullinger, John, Rahim, Tahrima, Rendon, Augusto, Rogers, Tim, Savage, Kevin, Sawant, Kushmita, Scott, Richard H, Siddiq, Afshan, Sieghart, Alexander, Smith, Samuel C, Sosinsky, Alona, Stuckey, Alexander, Tanguy, Mélanie, Taylor Tavares, Ana Lisa, Thomas, Ellen R A, Thompson, Simon R, Tucci, Arianna, Welland, Matthew J, Williams, Eleanor, Witkowska, Katarzyna, Wood, Suzanne M
Publicado 2021