Positive Correlation between nNOS and Stress-Activated Bowel Motility Is Confirmed by In Vivo HiBiT System

por Han, Jeong Pil, Lee, Jeong Hyeon, Lee, Geon Seong, Koo, Ok Jae, Yeom, Su Cheong
Publicado 2021

Novel Severe Hemophilia A Mouse Model with Factor VIII Intron 22 Inversion

por Han, Jeong Pil, Song, Dong Woo, Lee, Jeong Hyeon, Lee, Geon Seong, Yeom, Su Cheong
Publicado 2021

High Homology-Directed Repair Using Mitosis Phase and Nucleus Localizing Signal

por Han, Jeong Pil, Chang, Yoo Jin, Song, Dong Woo, Choi, Beom Seok, Koo, Ok Jae, Yi, Seung Youn, Park, Tae Sub, Yeom, Su Cheong
Publicado 2020

In vivo genome editing using 244-cis LNPs and low-dose AAV achieves therapeutic threshold in hemophilia A mice

por Han, Jeong Pil, Lee, Yeji, Lee, Jeong Hyeon, Chung, Hye Yoon, Lee, Geon Seong, Nam, Yu Ri, Choi, Myeongjin, Moon, Kyoung-Sik, Lee, Haeshin, Lee, Hyukjin, Yeom, Su Cheong
Publicado 2023

The position of the target site for engineered nucleases improves the aberrant mRNA clearance in in vivo genome editing

por Lee, Jae Hoon, Yu, Sungsook, Nam, Tae Wook, Roh, Jae-il, Jin, Young, Han, Jeong Pil, Cha, Ji-Young, Kim, Yoon Ki, Yeom, Su-Cheong, Nam, Ki Taek, Lee, Han-Woong
Publicado 2020

Morc2a p.S87L mutant mice develop peripheral and central neuropathies associated with neuronal DNA damage and apoptosis

por Lee, Geon Seong, Kwak, Geon, Bae, Ji Hyun, Han, Jeong Pil, Nam, Soo Hyun, Lee, Jeong Hyeon, Song, Sumin, Kim, Gap-Don, Park, Tae Sub, Choi, Yang Kyu, Choi, Byung-Ok, Yeom, Su Cheong
Publicado 2021

Genome editing-mediated knock-in of therapeutic genes ameliorates the disease phenotype in a model of hemophilia

por Lee, Jeong Hyeon, Oh, Hye-Kyung, Choi, Beom Seok, Lee, Ho Hyeon, Lee, Kyu Jun, Kim, Un Gi, Lee, Jina, Lee, Hyerim, Lee, Geon Seong, Ahn, Se Jun, Han, Jeong Pil, Kim, Seokjoong, Yeom, Su Cheong, Song, Dong Woo
Publicado 2022

In vivo delivery of CRISPR-Cas9 using lipid nanoparticles enables antithrombin gene editing for sustainable hemophilia A and B therapy

por Han, Jeong Pil, Kim, MinJeong, Choi, Beom Seok, Lee, Jeong Hyeon, Lee, Geon Seong, Jeong, Michaela, Lee, Yeji, Kim, Eun-Ah, Oh, Hye-Kyung, Go, Nanyeong, Lee, Hyerim, Lee, Kyu Jun, Kim, Un Gi, Lee, Jae Young, Kim, Seokjoong, Chang, Jun, Lee, Hyukjin, Song, Dong Woo, Yeom, Su Cheong
Publicado 2022