Protocol for rapid manipulation of mitochondrial morphology in living cells using inducible counter mitochondrial morphology (iCMM)

por Miyamoto, Takafumi, Han, Song-Iee, Shimano, Hitoshi
Publicado 2021

CREBH Systemically Regulates Lipid Metabolism by Modulating and Integrating Cellular Functions

por Nakagawa, Yoshimi, Araki, Masaya, Han, Song-iee, Mizunoe, Yuhei, Shimano, Hitoshi
Publicado 2021

The Peroxisome Proliferator-Activated Receptor α (PPARα) Agonist Pemafibrate Protects against Diet-Induced Obesity in Mice

por Araki, Masaya, Nakagawa, Yoshimi, Oishi, Asayo, Han, Song-iee, Wang, Yunong, Kumagai, Kae, Ohno, Hiroshi, Mizunoe, Yuhei, Iwasaki, Hitoshi, Sekiya, Motohiro, Matsuzaka, Takashi, Shimano, Hitoshi
Publicado 2018

CREB3L3 controls fatty acid oxidation and ketogenesis in synergy with PPARα

por Nakagawa, Yoshimi, Satoh, Aoi, Tezuka, Hitomi, Han, Song-iee, Takei, Kenta, Iwasaki, Hitoshi, Yatoh, Shigeru, Yahagi, Naoya, Suzuki, Hiroaki, Iwasaki, Yasumasa, Sone, Hirohito, Matsuzaka, Takashi, Yamada, Nobuhiro, Shimano, Hitoshi
Publicado 2016

Selective peroxisome proliferator‐activated receptor‐α modulator K‐877 efficiently activates the peroxisome proliferator‐activated receptor‐α pathway and improves lipid metabolism...

por Takei, Kenta, Han, Song‐iee, Murayama, Yuki, Satoh, Aoi, Oikawa, Fusaka, Ohno, Hiroshi, Osaki, Yoshinori, Matsuzaka, Takashi, Sekiya, Motohiro, Iwasaki, Hitoshi, Yatoh, Shigeru, Yahagi, Naoya, Suzuki, Hiroaki, Yamada, Nobuhiro, Nakagawa, Yoshimi, Shimano, Hitoshi
Publicado 2017

CREBH Improves Diet-Induced Obesity, Insulin Resistance, and Metabolic Disturbances by FGF21-Dependent and FGF21-Independent Mechanisms

por Satoh, Aoi, Han, Song-iee, Araki, Masaya, Nakagawa, Yoshimi, Ohno, Hiroshi, Mizunoe, Yuhei, Kumagai, Kae, Murayama, Yuki, Osaki, Yoshinori, Iwasaki, Hitoshi, Sekiya, Motohiro, Konishi, Morichika, Itoh, Nobuyuki, Matsuzaka, Takashi, Sone, Hirohito, Shimano, Hitoshi
Publicado 2020

Different Effects of Eicosapentaenoic and Docosahexaenoic Acids on Atherogenic High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice

por Suzuki-Kemuriyama, Noriko, Matsuzaka, Takashi, Kuba, Motoko, Ohno, Hiroshi, Han, Song-iee, Takeuchi, Yoshinori, Isaka, Masaaki, Kobayashi, Kazuto, Iwasaki, Hitoshi, Yatoh, Shigeru, Suzuki, Hiroaki, Miyajima, Katsuhiro, Nakae, Dai, Yahagi, Naoya, Nakagawa, Yoshimi, Sone, Hirohito, Yamada, Nobuhiro, Shimano, Hitoshi
Publicado 2016

Enterohepatic Transcription Factor CREB3L3 Protects Atherosclerosis via SREBP Competitive Inhibition

por Nakagawa, Yoshimi, Wang, Yunong, Han, Song-iee, Okuda, Kanako, Oishi, Asayo, Yagishita, Yuka, Kumagai, Kae, Ohno, Hiroshi, Osaki, Yoshinori, Mizunoe, Yuhei, Araki, Masaya, Murayama, Yuki, Iwasaki, Hitoshi, Konishi, Morichika, Itoh, Nobuyuki, Matsuzaka, Takashi, Sone, Hirohito, Yamada, Nobuhiro, Shimano, Hitoshi
Publicado 2020

Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression

por Kikuchi, Takuya, Orihara, Kana, Oikawa, Fusaka, Han, Song-iee, Kuba, Motoko, Okuda, Kanako, Satoh, Aoi, Osaki, Yoshinori, Takeuchi, Yoshinori, Aita, Yuichi, Matsuzaka, Takashi, Iwasaki, Hitoshi, Yatoh, Shigeru, Sekiya, Motohiro, Yahagi, Naoya, Suzuki, Hiroaki, Sone, Hirohito, Nakagawa, Yoshimi, Yamada, Nobuhiro, Shimano, Hitoshi
Publicado 2016

Rapid manipulation of mitochondrial morphology in a living cell with iCMM

por Miyamoto, Takafumi, Uosaki, Hideki, Mizunoe, Yuhei, Han, Song-Iee, Goto, Satoi, Yamanaka, Daisuke, Masuda, Masato, Yoneyama, Yosuke, Nakamura, Hideki, Hattori, Naoko, Takeuchi, Yoshinori, Ohno, Hiroshi, Sekiya, Motohiro, Matsuzaka, Takashi, Hakuno, Fumihiko, Takahashi, Shin-Ichiro, Yahagi, Naoya, Ito, Koichi, Shimano, Hitoshi
Publicado 2021

Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system

por Nakagawa, Yoshimi, Oikawa, Fusaka, Mizuno, Seiya, Ohno, Hiroshi, Yagishita, Yuka, Satoh, Aoi, Osaki, Yoshinori, Takei, Kenta, Kikuchi, Takuya, Han, Song-iee, Matsuzaka, Takashi, Iwasaki, Hitoshi, Kobayashi, Kazuto, Yatoh, Shigeru, Yahagi, Naoya, Isaka, Masaaki, Suzuki, Hiroaki, Sone, Hirohito, Takahashi, Satoru, Yamada, Nobuhiro, Shimano, Hitoshi
Publicado 2016

Absence of Elovl6 attenuates steatohepatitis but promotes gallstone formation in a lithogenic diet-fed Ldlr(−/−) mouse model

por Kuba, Motoko, Matsuzaka, Takashi, Matsumori, Rie, Saito, Ryo, Kaga, Naoko, Taka, Hikari, Ikehata, Kei, Okada, Naduki, Kikuchi, Takuya, Ohno, Hiroshi, Han, Song-iee, Takeuchi, Yoshinori, Kobayashi, Kazuto, Iwasaki, Hitoshi, Yatoh, Shigeru, Suzuki, Hiroaki, Sone, Hirohito, Yahagi, Naoya, Arakawa, Yoji, Fujimura, Tsutomu, Nakagawa, Yoshimi, Yamada, Nobuhiro, Shimano, Hitoshi
Publicado 2015

Octacosanol and policosanol prevent high-fat diet-induced obesity and metabolic disorders by activating brown adipose tissue and improving liver metabolism

por Sharma, Rahul, Matsuzaka, Takashi, Kaushik, Mahesh K., Sugasawa, Takehito, Ohno, Hiroshi, Wang, Yunong, Motomura, Kaori, Shimura, Takuya, Okajima, Yuka, Mizunoe, Yuhei, Ma, Yang, Saber, Zahara M., Iwasaki, Hitoshi, Yatoh, Shigeru, Suzuki, Hiroaki, Aita, Yuichi, Han, Song-iee, Takeuchi, Yoshinori, Yahagi, Naoya, Miyamoto, Takafumi, Sekiya, Motohiro, Nakagawa, Yoshimi, Shimano, Hitoshi
Publicado 2019

Rhomboid protease RHBDL4/RHBDD1 cleaves SREBP-1c at endoplasmic reticulum monitoring and regulating fatty acids

por Han, Song-Iee, Nakakuki, Masanori, Nakagawa, Yoshimi, Wang, Yunong, Araki, Masaya, Yamamoto, Yuta, Tokiwa, Hiroaki, Takeda, Hiroyuki, Mizunoe, Yuhei, Motomura, Kaori, Ohno, Hiroshi, Kainoh, Kenta, Murayama, Yuki, Aita, Yuichi, Takeuchi, Yoshinori, Osaki, Yoshinori, Miyamoto, Takafumi, Sekiya, Motohiro, Matsuzaka, Takashi, Yahagi, Naoya, Sone, Hirohito, Daitoku, Hiroaki, Sato, Ryuichiro, Kawano, Hiroyuki, Shimano, Hitoshi
Publicado 2023

Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity

por Saito, Kenji, Sekiya, Motohiro, Kainoh, Kenta, Yoshino, Ryunosuke, Hayashi, Akio, Han, Song-Iee, Araki, Masaya, Ohno, Hiroshi, Takeuchi, Yoshinori, Tsuyuzaki, Tomomi, Yamazaki, Daichi, Wanpei, Chen, Hada, Lisa, Watanabe, Sho, Paramita Adi Putri, Putu Indah, Murayama, Yuki, Sugano, Yoko, Osaki, Yoshinori, Iwasaki, Hitoshi, Yahagi, Naoya, Suzuki, Hiroaki, Miyamoto, Takafumi, Matsuzaka, Takashi, Shimano, Hitoshi
Publicado 2023