Shared genomic architecture between COVID-19 severity and numerous clinical and physiologic parameters revealed by LD score regression analysis

por Byun, Jinyoung, Han, Younghun, Walsh, Kyle M., Park, Amy S., Bondy, Melissa L., Amos, Christopher I.
Publicado 2022

Ancestry inference using principal component analysis and spatial analysis: a distance-based analysis to account for population substructure

por Byun, Jinyoung, Han, Younghun, Gorlov, Ivan P., Busam, Jonathan A., Seldin, Michael F., Amos, Christopher I.
Publicado 2017

A comprehensive analysis of lung cancer highlighting epidemiological factors and psychiatric comorbidities from the All of Us Research Program

por Shaw, Vikram R., Byun, Jinyoung, Pettit, Rowland W., Han, Younghun, Hsiou, David A., Nordstrom, Luke A., Amos, Christopher I.
Publicado 2023

Genome-wide gene–environment interaction analysis for asbestos exposure in lung cancer susceptibility

por Wei, Sheng, Wang, Li-E, McHugh, Michelle K., Han, Younghun, Xiong, Momiao, Amos, Christopher I., Spitz, Margaret R., Wei, Qingyi Wei
Publicado 2012

Disentangling the aetiological pathways between body mass index and site-specific cancer risk using tissue-partitioned Mendelian randomisation

por Leyden, Genevieve M., Greenwood, Michael P., Gaborieau, Valérie, Han, Younghun, Amos, Christopher I., Brennan, Paul, Murphy, David, Davey Smith, George, Richardson, Tom G.
Publicado 2022

Individual-Level Determinants of Lifestyle Behavioral Changes during COVID-19 Lockdown in the United States: Results of an Online Survey

por Zhang, Xiaotao, Oluyomi, Abiodun, Woodard, LeChauncy, Raza, Syed Ahsan, Adel Fahmideh, Maral, El-Mubasher, Ola, Byun, Jinyoung, Han, Younghun, Amos, Christopher I., Badr, Hoda
Publicado 2021

Effects of MDM2, MDM4 and TP53 Codon 72 Polymorphisms on Cancer Risk in a Cohort Study of Carriers of TP53 Germline Mutations

por Fang, Shenying, Krahe, Ralf, Lozano, Guillermina, Han, Younghun, Chen, Wei, Post, Sean M., Zhang, Baili, Wilson, Charmaine D., Bachinski, Linda L., Strong, Louise C., Amos, Christopher I.
Publicado 2010

FastPop: a rapid principal component derived method to infer intercontinental ancestry using genetic data

por Li, Yafang, Byun, Jinyoung, Cai, Guoshuai, Xiao, Xiangjun, Han, Younghun, Cornelis, Olivier, Dinulos, James E., Dennis, Joe, Easton, Douglas, Gorlov, Ivan, Seldin, Michael F., Amos, Christopher I.
Publicado 2016

The shared genetic architecture between epidemiological and behavioral traits with lung cancer

por Pettit, Rowland W., Byun, Jinyoung, Han, Younghun, Ostrom, Quinn T., Edelson, Jacob, Walsh, Kyle M., Bondy, Melissa L., Hung, Rayjean J., McKay, James D., Amos, Christopher I.
Publicado 2021

Rev-erb in GABAergic Neurons Controls Diurnal Hepatic Insulin Sensitivity

por Ding, Guolian, Li, Xin, Hou, Xinguo, Zhou, Wenjun, Gong, Yingyun, Liu, Fuqiang, He, Yanlin, Song, Jia, Wang, Jing, Basil, Paul, Li, Wenbo, Qian, Sichong, Saha, Pradip, Wang, Jinbang, Cui, Chen, Yang, Tingting, Zou, Kexin, Han, Younghun, Amos, Christopher I., Xu, Yong, Chen, Li, Sun, Zheng
Publicado 2021

Context-aware single-cell multiome approach identified cell-type specific lung cancer susceptibility genes

por Long, Erping, Yin, Jinhu, Shin, Ju Hye, Li, Yuyan, Kane, Alexander, Patel, Harsh, Luong, Thong, Xia, Jun, Han, Younghun, Byun, Jinyoung, Zhang, Tongwu, Zhao, Wei, Landi, Maria Teresa, Rothman, Nathaniel, Lan, Qing, Chang, Yoon Soo, Yu, Fulong, Amos, Christopher, Shi, Jianxin, Lee, Jin Gu, Kim, Eun Young, Choi, Jiyeon
Publicado 2023

Genetic variants of PTPN2 are associated with lung cancer risk: a re-analysis of eight GWASs in the TRICL-ILCCO consortium

por Feng, Yun, Wang, Yanru, Liu, Hongliang, Liu, Zhensheng, Mills, Coleman, Han, Younghun, Hung, Rayjean J., Brhane, Yonathan, McLaughlin, John, Brennan, Paul, Bickeboeller, Heike, Rosenberger, Albert, Houlston, Richard S., Caporaso, Neil E., Teresa Landi, Maria, Brueske, Irene, Risch, Angela, Ye, Yuanqing, Wu, Xifeng, Christiani, David C., Amos, Christopher I., Wei, Qingyi
Publicado 2017

Deciphering associations between three RNA splicing-related genetic variants and lung cancer risk

por Yang, Wenjun, Liu, Hongliang, Zhang, Ruoxin, Freedman, Jennifer A., Han, Younghun, Hung, Rayjean J., Brhane, Yonathan, McLaughlin, John, Brennan, Paul, Bickeboeller, Heike, Rosenberger, Albert, Houlston, Richard S., Caporaso, Neil E., Landi, Maria Teresa, Brueske, Irene, Risch, Angela, Christiani, David C., Amos, Christopher I., Chen, Xiaoxin, Patierno, Steven R., Wei, Qingyi
Publicado 2022

A Novel Genetic Variant in Long Non-coding RNA Gene NEXN-AS1 is Associated with Risk of Lung Cancer

por Yuan, Hua, Liu, Hongliang, Liu, Zhensheng, Owzar, Kouros, Han, Younghun, Su, Li, Wei, Yongyue, Hung, Rayjean J., McLaughlin, John, Brhane, Yonathan, Brennan, Paul, Bickeboeller, Heike, Rosenberger, Albert, Houlston, Richard S., Caporaso, Neil, Landi, Maria Teresa, Heinrich, Joachim, Risch, Angela, Christiani, David C., Gümüş, Zeynep H., Klein, Robert J., Amos, Christopher I., Wei, Qingyi
Publicado 2016

Associations between genetic variants in mRNA splicing-related genes and risk of lung cancer: a pathway-based analysis from published GWASs

por Pan, Yongchu, Liu, Hongliang, Wang, Yanru, Kang, Xiaozheng, Liu, Zhensheng, Owzar, Kouros, Han, Younghun, Su, Li, Wei, Yongyue, Hung, Rayjean J., Brhane, Yonathan, McLaughlin, John, Brennan, Paul, Bickeböller, Heike, Rosenberger, Albert, Houlston, Richard S., Caporaso, Neil, Teresa Landi, Maria, Heinrich, Joachim, Risch, Angela, Wu, Xifeng, Ye, Yuanqing, Christiani, David C., Amos, Christopher I., Wei, Qingyi
Publicado 2017

International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways

por Cordell, Heather J., Han, Younghun, Mells, George F., Li, Yafang, Hirschfield, Gideon M., Greene, Casey S., Xie, Gang, Juran, Brian D., Zhu, Dakai, Qian, David C., Floyd, James A. B., Morley, Katherine I., Prati, Daniele, Lleo, Ana, Cusi, Daniele, Gershwin, M. Eric, Anderson, Carl A., Lazaridis, Konstantinos N., Invernizzi, Pietro, Seldin, Michael F., Sandford, Richard N., Amos, Christopher I., Siminovitch, Katherine A.
Publicado 2015

Multitrait genome-wide analyses identify new susceptibility loci and candidate drugs to primary sclerosing cholangitis

por Han, Younghun, Byun, Jinyoung, Zhu, Catherine, Sun, Ryan, Roh, Julia Y., Cordell, Heather J., Lee, Hyun-Sung, Shaw, Vikram R., Kang, Sung Wook, Razjouyan, Javad, Cooley, Matthew A., Hassan, Manal M., Siminovitch, Katherine A., Folseraas, Trine, Ellinghaus, David, Bergquist, Annika, Rushbrook, Simon M., Franke, Andre, Karlsen, Tom H., Lazaridis, Konstantinos N., McGlynn, Katherine A., Roberts, Lewis R., Amos, Christopher I.
Publicado 2023

Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148

por Fang, Jun, Jia, Jinping, Makowski, Matthew, Xu, Mai, Wang, Zhaoming, Zhang, Tongwu, Hoskins, Jason W., Choi, Jiyeon, Han, Younghun, Zhang, Mingfeng, Thomas, Janelle, Kovacs, Michael, Collins, Irene, Dzyadyk, Marta, Thompson, Abbey, O'Neill, Maura, Das, Sudipto, Lan, Qi, Koster, Roelof, Stolzenberg-Solomon, Rachael S., Kraft, Peter, Wolpin, Brian M., Jansen, Pascal W. T. C., Olson, Sara, McGlynn, Katherine A., Kanetsky, Peter A., Chatterjee, Nilanjan, Barrett, Jennifer H., Dunning, Alison M., Taylor, John C., Newton-Bishop, Julia A., Bishop, D. Timothy, Andresson, Thorkell, Petersen, Gloria M., Amos, Christopher I., Iles, Mark M., Nathanson, Katherine L., Landi, Maria Teresa, Vermeulen, Michiel, Brown, Kevin M., Amundadottir, Laufey T.
Publicado 2017

Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence

por Hancock, Dana B., Guo, Yuelong, Reginsson, Gunnar W., Gaddis, Nathan C., Lutz, Sharon M., Sherva, Richard, Loukola, Anu, Minica, Camelia, Markunas, Christina A., Han, Younghun, Young, Kendra A., Gudbjartsson, Daniel F., Gu, Fangyi, McNeil, Daniel W., Qaiser, Beenish, Glasheen, Cristie, Olson, Sean, Landi, Maria Teresa, Madden, Pamela A. F., Farrer, Lindsay A., Vink, Jacqueline, Saccone, Nancy L., Neale, Michael C., Kranzler, Henry R., McKay, James, Hung, Rayjean J., Amos, Christopher I., Marazita, Mary L., Boomsma, Dorret I., Baker, Timothy B., Gelernter, Joel, Kaprio, Jaakko, Caporaso, Neil E., Thorgeirsson, Thorgeir E., Hokanson, John E., Bierut, Laura J., Stefansson, Kari, Johnson, Eric O.
Publicado 2017

Publisher correction: Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148

por Fang, Jun, Jia, Jinping, Makowski, Matthew, Xu, Mai, Wang, Zhaoming, Zhang, Tongwu, Hoskins, Jason W., Choi, Jiyeon, Han, Younghun, Zhang, Mingfeng, Thomas, Janelle, Kovacs, Michael, Collins, Irene, Dzyadyk, Marta, Thompson, Abbey, O'Neill, Maura, Das, Sudipto, Lan, Qi, Koster, Roelof, Stolzenberg-Solomon, Rachael S., Kraft, Peter, Wolpin, Brian M., Jansen, Pascal W. T. C., Olson, Sara, McGlynn, Katherine A., Kanetsky, Peter A., Chatterjee, Nilanjan, Barrett, Jennifer H., Dunning, Alison M., Taylor, John C., Newton-Bishop, Julia A., Timothy Bishop, D, Andresson, Thorkell, Petersen, Gloria M., Amos, Christopher I., Iles, Mark M., Nathanson, Katherine L., Teresa Landi, Maria, Vermeulen, Michiel, Brown, Kevin M., Amundadottir, Laufey T.
Publicado 2018