Mechanistic basis for potent neutralization of Sin Nombre hantavirus by a human monoclonal antibody

por Stass, Robert, Engdahl, Taylor B., Chapman, Nathaniel S., Wolters, Rachael M., Handal, Laura S., Diaz, Summer M., Crowe, James E., Bowden, Thomas A.
Publicado 2023

A highly potent human neutralizing antibody prevents vertical transmission of Rift Valley fever virus in a rat model

por McMillen, Cynthia M., Chapman, Nathaniel S., Hoehl, Ryan M., Skvarca, Lauren B., Schwarz, Madeline M., Handal, Laura S., Crowe, James E., Hartman, Amy L.
Publicado 2023

Potently neutralizing human mAbs against the zoonotic pararubulavirus Sosuga virus

por Parrington, Helen M., Kose, Nurgun, Armstrong, Erica, Handal, Laura, Diaz, Summer, Reidy, Joseph, Dong, Jinhui, Stewart-Jones, Guillaume B.E., Shrivastava-Ranjan, Punya, Jain, Shilpi, Albariño, César G., Carnahan, Robert H., Crowe, James E.
Publicado 2023

Multifunctional human monoclonal antibody combination mediates protection against Rift Valley fever virus at low doses

por Chapman, Nathaniel S., Hulswit, Ruben J. G., Westover, Jonna L. B., Stass, Robert, Paesen, Guido C., Binshtein, Elad, Reidy, Joseph X., Engdahl, Taylor B., Handal, Laura S., Flores, Alejandra, Gowen, Brian B., Bowden, Thomas A., Crowe, James E.
Publicado 2023

An antibody targeting the N-terminal domain of SARS-CoV-2 disrupts the spike trimer

por Suryadevara, Naveenchandra, Shiakolas, Andrea R., VanBlargan, Laura A., Binshtein, Elad, Chen, Rita E., Case, James Brett, Kramer, Kevin J., Armstrong, Erica C., Myers, Luke, Trivette, Andrew, Gainza, Christopher, Nargi, Rachel S., Selverian, Christopher N., Davidson, Edgar, Doranz, Benjamin J., Diaz, Summer M., Handal, Laura S., Carnahan, Robert H., Diamond, Michael S., Georgiev, Ivelin S., Crowe, James E.
Publicado 2022

Antigenic mapping and functional characterization of human New World hantavirus neutralizing antibodies

por Engdahl, Taylor B, Binshtein, Elad, Brocato, Rebecca L, Kuzmina, Natalia A, Principe, Lucia M, Kwilas, Steven A, Kim, Robert K, Chapman, Nathaniel S, Porter, Monique S, Guardado-Calvo, Pablo, Rey, Félix A, Handal, Laura S, Diaz, Summer M, Zagol-Ikapitte, Irene A, Tran, Minh H, McDonald, W Hayes, Meiler, Jens, Reidy, Joseph X, Trivette, Andrew, Bukreyev, Alexander, Hooper, Jay W, Crowe, James E
Publicado 2023

Computationally restoring the potency of a clinical antibody against SARS-CoV-2 Omicron subvariants

por Desautels, Thomas A., Arrildt, Kathryn T., Zemla, Adam T., Lau, Edmond Y., Zhu, Fangqiang, Ricci, Dante, Cronin, Stephanie, Zost, Seth J., Binshtein, Elad, Scheaffer, Suzanne M., Dadonaite, Bernadeta, Petersen, Brenden K., Engdahl, Taylor B., Chen, Elaine, Handal, Laura S., Hall, Lynn, Goforth, John W., Vashchenko, Denis, Nguyen, Sam, Weilhammer, Dina R., Lo, Jacky Kai-Yin, Rubinfeld, Bonnee, Saada, Edwin A., Weisenberger, Tracy, Lee, Tek-Hyung, Whitener, Bradley, Case, James B., Ladd, Alexander, Silva, Mary S., Haluska, Rebecca M., Grzesiak, Emilia A., Earnhart, Christopher G., Hopkins, Svetlana, Bates, Thomas W., Thackray, Larissa B., Segelke, Brent W., Lillo, Antonietta Maria, Sundaram, Shivshankar, Bloom, Jesse, Diamond, Michael S., Crowe, James E., Carnahan, Robert H., Faissol, Daniel M.
Publicado 2023