Phenotypic lentivirus screens to identify functional single domain antibodies

por Schmidt, Florian I., Hanke, Leo, Morin, Benjamin, Brewer, Rebeccah, Brusic, Vesna, Whelan, Sean P.J., Ploegh, Hidde L.
Publicado 2016

DNA-launched RNA replicon vaccines induce potent anti-SARS-CoV-2 immune responses in mice

por Szurgot, Inga, Hanke, Leo, Sheward, Daniel J., Vidakovics, Laura Perez, Murrell, Ben, McInerney, Gerald M., Liljeström, Peter
Publicado 2021

Picomolar SARS-CoV-2 Neutralization Using Multi-Arm PEG Nanobody Constructs

por Moliner-Morro, Ainhoa, J. Sheward, Daniel, Karl, Vivien, Perez Vidakovics, Laura, Murrell, Ben, McInerney, Gerald M., Hanke, Leo
Publicado 2020

The Antiviral Mechanism of an Influenza A Virus Nucleoprotein-Specific Single-Domain Antibody Fragment

por Hanke, Leo, Knockenhauer, Kevin E., Brewer, R. Camille, van Diest, Eline, Schmidt, Florian I., Schwartz, Thomas U., Ploegh, Hidde L.
Publicado 2016

A Multiparametric and High-Throughput Platform for Host–Virus Binding Screens

por Schlegel, Jan, Porebski, Bartlomiej, Andronico, Luca, Hanke, Leo, Edwards, Steven, Brismar, Hjalmar, Murrell, Ben, McInerney, Gerald M., Fernandez-Capetillo, Oscar, Sezgin, Erdinc
Publicado 2023

Silver nanoparticles with excellent biocompatibility block pseudotyped SARS-CoV-2 in the presence of lung surfactant

por Gupta, Govind, Hamawandi, Bejan, Sheward, Daniel J., Murrell, Ben, Hanke, Leo, McInerney, Gerald, Blosi, Magda, Costa, Anna L., Toprak, Muhammet S., Fadeel, Bengt
Publicado 2022

Adjuvanted SARS-CoV-2 spike protein elicits neutralizing antibodies and CD4 T cell responses after a single immunization in mice

por Wørzner, Katharina, Sheward, Daniel J., Schmidt, Signe Tandrup, Hanke, Leo, Zimmermann, Julie, McInerney, Gerald, Hedestam, Gunilla B. Karlsson, Murrell, Ben, Christensen, Dennis, Pedersen, Gabriel Kristian
Publicado 2021

An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction

por Hanke, Leo, Vidakovics Perez, Laura, Sheward, Daniel J., Das, Hrishikesh, Schulte, Tim, Moliner-Morro, Ainhoa, Corcoran, Martin, Achour, Adnane, Karlsson Hedestam, Gunilla B., Hällberg, B. Martin, Murrell, Ben, McInerney, Gerald M.
Publicado 2020

Multivariate mining of an alpaca immune repertoire identifies potent cross-neutralizing SARS-CoV-2 nanobodies

por Hanke, Leo, Sheward, Daniel J., Pankow, Alec, Vidakovics, Laura Perez, Karl, Vivien, Kim, Changil, Urgard, Egon, Smith, Natalie L., Astorga-Wells, Juan, Ekström, Simon, Coquet, Jonathan M., McInerney, Gerald M., Murrell, Ben
Publicado 2022

Beta RBD boost broadens antibody-mediated protection against SARS-CoV-2 variants in animal models

por Sheward, Daniel J., Mandolesi, Marco, Urgard, Egon, Kim, Changil, Hanke, Leo, Perez Vidakovics, Laura, Pankow, Alec, Smith, Natalie L., Castro Dopico, Xaquin, McInerney, Gerald M., Coquet, Jonathan M., Karlsson Hedestam, Gunilla B., Murrell, Ben
Publicado 2021

SARS-CoV-2 protein subunit vaccination of mice and rhesus macaques elicits potent and durable neutralizing antibody responses

por Mandolesi, Marco, Sheward, Daniel J., Hanke, Leo, Ma, Junjie, Pushparaj, Pradeepa, Perez Vidakovics, Laura, Kim, Changil, Àdori, Monika, Lenart, Klara, Loré, Karin, Castro Dopico, Xaquin, Coquet, Jonathan M., McInerney, Gerald M., Karlsson Hedestam, Gunilla B., Murrell, Ben
Publicado 2021

Probabilistic classification of anti‐SARS‐CoV‐2 antibody responses improves seroprevalence estimates

por Castro Dopico, Xaquin, Muschiol, Sandra, Grinberg, Nastasiya F, Aleman, Soo, Sheward, Daniel J, Hanke, Leo, Ahl, Marcus, Vikström, Linnea, Forsell, Mattias, Coquet, Jonathan M, McInerney, Gerald, Dillner, Joakim, Bogdanovic, Gordana, Murrell, Ben, Albert, Jan, Wallace, Chris, Karlsson Hedestam, Gunilla B
Publicado 2022

Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies

por Pushparaj, Pradeepa, Nicoletto, Andrea, Sheward, Daniel J., Das, Hrishikesh, Castro Dopico, Xaquin, Perez Vidakovics, Laura, Hanke, Leo, Chernyshev, Mark, Narang, Sanjana, Kim, Sungyong, Fischbach, Julian, Ekström, Simon, McInerney, Gerald, Hällberg, B. Martin, Murrell, Ben, Corcoran, Martin, Karlsson Hedestam, Gunilla B.
Publicado 2023

SARS-CoV-2 spike HexaPro formulated in aluminium hydroxide and administered in an accelerated vaccination schedule partially protects Syrian Hamsters against viral challenge despit...

por Christensen, Dennis, Polacek, Charlotta, Sheward, Daniel J., Hanke, Leo, McInerney, Gerald, Murrell, Ben, Hartmann, Katrine Top, Jensen, Henrik Elvang, Zimmermann, Julie, Jungersen, Gregers, Illigen, Kristin Engelhart, Isling, Louise Krag, Fernandez-Antunez, Carlota, Ramirez, Santseharay, Bukh, Jens, Pedersen, Gabriel Kristian
Publicado 2023

Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH

por Schulte, Tim, Panas, Marc D., Han, Xiao, Williams, Lucy, Kedersha, Nancy, Fleck, Jonas Simon, Tan, Timothy J. C., Dopico, Xaquin Castro, Olsson, Anders, Morro, Ainhoa Moliner, Hanke, Leo, Nilvebrant, Johan, Giang, Kim Anh, Nygren, Per-Åke, Anderson, Paul, Achour, Adnane, McInerney, Gerald M.
Publicado 2023

Multianalyte serology in home-sampled blood enables an unbiased assessment of the immune response against SARS-CoV-2

por Roxhed, Niclas, Bendes, Annika, Dale, Matilda, Mattsson, Cecilia, Hanke, Leo, Dodig-Crnković, Tea, Christian, Murray, Meineke, Birthe, Elsässer, Simon, Andréll, Juni, Havervall, Sebastian, Thålin, Charlotte, Eklund, Carina, Dillner, Joakim, Beck, Olof, Thomas, Cecilia E., McInerney, Gerald, Hong, Mun-Gwan, Murrell, Ben, Fredolini, Claudia, Schwenk, Jochen M.
Publicado 2021

A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo

por Hanke, Leo, Das, Hrishikesh, Sheward, Daniel J., Perez Vidakovics, Laura, Urgard, Egon, Moliner-Morro, Ainhoa, Kim, Changil, Karl, Vivien, Pankow, Alec, Smith, Natalie L., Porebski, Bartlomiej, Fernandez-Capetillo, Oscar, Sezgin, Erdinc, Pedersen, Gabriel K., Coquet, Jonathan M., Hällberg, B. Martin, Murrell, Ben, McInerney, Gerald M.
Publicado 2022

Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2

por Custódio, Tânia F., Das, Hrishikesh, Sheward, Daniel J., Hanke, Leo, Pazicky, Samuel, Pieprzyk, Joanna, Sorgenfrei, Michèle, Schroer, Martin A., Gruzinov, Andrey Yu., Jeffries, Cy M., Graewert, Melissa A., Svergun, Dmitri I., Dobrev, Nikolay, Remans, Kim, Seeger, Markus A., McInerney, Gerald M., Murrell, Ben, Hällberg, B. Martin, Löw, Christian
Publicado 2020

Protection against SARS-CoV-2 transmission by a parenteral prime—Intranasal boost vaccine strategy

por Christensen, Dennis, Polacek, Charlotta, Sheward, Daniel J., Hanke, Leo, Moliner-Morro, Ainhoa, McInerney, Gerald, Murrell, Ben, Hartmann, Katrine Top, Jensen, Henrik Elvang, Jungersen, Gregers, Illigen, Kristin, Isling, Louise Krag, Jensen, Rune Fledelius, Hansen, Julia Sid, Rosenkrands, Ida, Fernandez-Antunez, Carlota, Ramirez, Santseharay, Follmann, Frank, Bukh, Jens, Pedersen, Gabriel Kristian
Publicado 2022

At-home sampling to meet geographical challenges for serological assessment of SARS-CoV-2 exposure in a rural region of northern Sweden, March to May 2021: a retrospective cohort s...

por Byström, Julia Wigren, Vikström, Linnea, Rosendal, Ebba, Gröning, Remigius, Gwon, Yong-Dae, Nilsson, Emma, Sharma, Atin, Espaillat, Akbar, Hanke, Leo, McInerney, Gerald, Puhar, Andrea, Cava, Felipe, Karlsson Hedestam, Gunilla B, Thunberg, Therese, Monsen, Tor, Elgh, Fredrik, Evander, Magnus, Johansson, Anders F, Överby, Anna K, Ahlm, Clas, Normark, Johan, Forsell, Mattias NE
Publicado 2023