Observations on morphologic changes in the aging and degenerating human disc: Secondary collagen alterations

por Gruber, Helen E, Hanley, Edward N
Publicado 2002

Do We Need Biomarkers for Disc Degeneration?

por Gruber, Helen E., Hanley, Edward N.
Publicado 2007

Human disc cells in monolayer vs 3D culture: cell shape, division and matrix formation

por Gruber, Helen E, Hanley, Edward N
Publicado 2000

Biological Effects of Phosphocitrate on Osteoarthritic Articular Chondrocytes

por Sun, Yubo, Franklin, Atiya M, Mauerhan, David R, Hanley, Edward N
Publicado 2017

Computer aided vertebral visualization and analysis: a methodology using the sand rat, a small animal model of disc degeneration

por Wilson, Christy, Brown, Darien, Najarian, Kayvan, Hanley, Edward N, Gruber, Helen E
Publicado 2003

Genome-wide analysis of pain-, nerve- and neurotrophin -related gene expression in the degenerating human annulus

por Gruber, Helen E, Hoelscher, Gretchen L, Ingram, Jane A, Hanley, Edward N
Publicado 2012

The role of inhibition by phosphocitrate and its analogue in chondrocyte differentiation and subchondral bone advance in Hartley guinea pigs

por Sun, Yubo, Kiraly, Alex J., Cox, Michael, Mauerhan, David R., Hanley, Edward N.
Publicado 2018

Senescent vs. non-senescent cells in the human annulus in vivo: Cell harvest with laser capture microdissection and gene expression studies with microarray analysis

por Gruber, Helen E, Hoelscher, Gretchen L, Ingram, Jane A, Zinchenko, Natalia, Hanley, Edward N
Publicado 2010

Mucin 1, a signal transduction membrane-bound mucin, is present in human disc tissue and is downregulated in vitro by exposure to IL-1ß or TNF-α

por Gruber, Helen E., Ingram, Jane A., Hoelscher, Gretchen L., Marrero, Emilio, Hanley, Edward N.
Publicado 2017

Adipose-derived mesenchymal stem cells from the sand rat: transforming growth factor beta and 3D co-culture with human disc cells stimulate proteoglycan and collagen type I rich ex...

por Tapp, Hazel, Deepe, Ray, Ingram, Jane A, Kuremsky, Marshall, Hanley, Edward N, Gruber, Helen E
Publicado 2008

Expression of Phosphocitrate-Targeted Genes in Osteoarthritis Menisci

por Sun, Yubo, Mauerhan, David R., Steuerwald, Nury M., Ingram, Jane, Kneisl, Jeffrey S., Hanley, Edward N.
Publicado 2014

Brain-derived neurotrophic factor and its receptor in the human and the sand rat intervertebral disc

por Gruber, Helen E, Ingram, Jane A, Hoelscher, Gretchen, Zinchenko, Natalia, Norton, H James, Hanley, Edward N
Publicado 2008

Asporin, a susceptibility gene in osteoarthritis, is expressed at higher levels in the more degenerate human intervertebral disc

por Gruber, Helen E, Ingram, Jane A, Hoelscher, Gretchen L, Zinchenko, Natalia, Hanley, Edward N, Sun, Yubo
Publicado 2009

Phosphocitrate Is Potentially a Disease-Modifying Drug for Noncrystal-Associated Osteoarthritis

por Sun, Yubo, Mauerhan, David R., Franklin, Atiya M., Norton, James, Hanley, Edward N., Gruber, Helen E.
Publicado 2013

Biological Activities of Phosphocitrate: A Potential Meniscal Protective Agent

por Sun, Yubo, Roberts, Andrea, Mauerhan, David R., Sun, Andrew R., Norton, H. James, Hanley, Edward N.
Publicado 2013

Matrix metalloproteinase 28, a novel matrix metalloproteinase, is constitutively expressed in human intervertebral disc tissue and is present in matrix of more degenerated discs

por Gruber, Helen E, Ingram, Jane A, Hoelscher, Gretchen L, Zinchenko, Natalia, Norton, H James, Hanley, Edward N
Publicado 2009

Constitutive expression of cathepsin K in the human intervertebral disc: new insight into disc extracellular matrix remodeling via cathepsin K and receptor activator of nuclear fac...

por Gruber, Helen E, Ingram, Jane A, Hoelscher, Gretchen L, Zinchenko, Natalia, Norton, H James, Hanley, Edward N
Publicado 2011

A Novel Catechol-O-Methyltransferase Variant Associated with Human Disc Degeneration

por Gruber, Helen E., Sha, Wei, Brouwer, Cory R., Steuerwald, Nury, Hoelscher, Gretchen L., Hanley, Edward N. Jr.
Publicado 2014

Expression and localization of estrogen receptor-β in annulus cells of the human intervertebral disc and the mitogenic effect of 17-β-estradiol in vitro

por Gruber, Helen E, Yamaguchi, Dean, Ingram, Jane, Leslie, Kelly, Huang, Weibiao, Miller, Timothy A, Hanley, Edward N
Publicado 2002

Three-dimensional culture of human meniscal cells: Extracellular matrix and proteoglycan production

por Gruber, Helen E, Mauerhan, David, Chow, Yin, Ingram, Jane A, Norton, H James, Hanley, Edward N, Sun, Yubo
Publicado 2008