Up-regulation of the PI3K/AKT and RHO/RAC/PAK signalling pathways in CHK1 inhibitor resistant Eµ-Myc lymphoma cells

por Hunter, Jill E., Campbell, Amy E., Kerridge, Scott, Fraser, Callum, Hannaway, Nicola L., Luli, Saimir, Ivanova, Iglika, Brownridge, Philip J., Coxhead, Jonathan, Taylor, Leigh, Leary, Peter, Hasoon, Megan S. R., Eyers, Claire E., Perkins, Neil D.
Publicado 2022

Mutation of the RelA(p65) Thr505 phosphosite disrupts the DNA replication stress response leading to CHK1 inhibitor resistance

por Hunter, Jill E., Campbell, Amy E., Butterworth, Jacqueline A., Sellier, Helene, Hannaway, Nicola L., Luli, Saimir, Floudas, Achilleas, Kenneth, Niall S., Moore, Adam J., Brownridge, Philip J., Thomas, Huw D., Coxhead, Jonathan, Taylor, Leigh, Leary, Peter, Hasoon, Megan S.R., Knight, Andrew M., Garrett, Michelle D., Collins, Ian, Eyers, Claire E., Perkins, Neil D.
Publicado 2022

Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway

por Hunter, Jill E., Campbell, Amy E., Hannaway, Nicola L., Kerridge, Scott, Luli, Saimir, Butterworth, Jacqueline A., Sellier, Helene, Mukherjee, Reshmi, Dhillon, Nikita, Sudhindar, Praveen D., Shukla, Ruchi, Brownridge, Philip J., Bell, Hayden L., Coxhead, Jonathan, Taylor, Leigh, Leary, Peter, Hasoon, Megan S.R., Collins, Ian, Garrett, Michelle D., Eyers, Claire E., Perkins, Neil D.
Publicado 2022