Trends in industrialization of biotherapeutics: a survey of product characteristics of 89 antibody-based biotherapeutics

por Martin, Kyle P., Grimaldi, Christine, Grempler, Rolf, Hansel, Steven, Kumar, Sandeep
Publicado 2023

Using quantitative systems pharmacology modeling to optimize combination therapy of anti-PD-L1 checkpoint inhibitor and T cell engager

por Anbari, Samira, Wang, Hanwen, Zhang, Yu, Wang, Jun, Pilvankar, Minu, Nickaeen, Masoud, Hansel, Steven, Popel, Aleksander S.
Publicado 2023

Development of novel ultra-sensitive IL-11 target engagement assays to support mechanistic PK/PD modeling for an anti-IL-11 antibody therapeutic

por Myzithras, Maria, Lin, Siqi, Radden, Legairre, Hess Kenny, Cynthia, Cai, Zheng, MacDonald, Angus, Binetti, Ralph, Marlow, Michael, Fracasso, Paul, Gibson, Glenn, Bartlett, Christina, Hawkins, Julie, Hansel, Steven
Publicado 2022

Retrospective analysis of model-based predictivity of human pharmacokinetics for anti-IL-36R monoclonal antibody MAB92 using a rat anti-mouse IL-36R monoclonal antibody and RNA exp...

por Ahlberg, Jennifer, Giragossian, Craig, Li, Hua, Myzithras, Maria, Raymond, Ernie, Caviness, Gary, Grimaldi, Christine, Brown, Su-Ellen, Perez, Rocio, Yang, Danlin, Kroe-Barrett, Rachel, Joseph, David, Pamulapati, Chandrasena, Coble, Kelly, Ruus, Peter, Woska, Joseph R., Ganesan, Rajkumar, Hansel, Steven, Mbow, M. Lamine
Publicado 2019