Whole-brain three-dimensional imaging for quantification of drug targets and treatment effects in mouse models of neurodegenerative diseases

por Hansen, Henrik H., Roostalu, Urmas, Hecksher-Sørensen, Jacob
Publicado 2020

Application of the Physical Disector Principle for Quantification of Dopaminergic Neuronal Loss in a Rat 6-Hydroxydopamine Nigral Lesion Model of Parkinson's Disease

por Fabricius, Katrine, Barkholt, Pernille, Jelsing, Jacob, Hansen, Henrik H.
Publicado 2017

Alterations in hypothalamic gene expression following Roux-en-Y gastric bypass

por Barkholt, Pernille, Pedersen, Philip J., Hay-Schmidt, Anders, Jelsing, Jacob, Hansen, Henrik H., Vrang, Niels
Publicado 2016

GABA(A) Receptor α Subunits Differentially Contribute to Diazepam Tolerance after Chronic Treatment

por Vinkers, Christiaan H., van Oorschot, Ruud, Nielsen, Elsebet Ø., Cook, James M., Hansen, Henrik H., Groenink, Lucianne, Olivier, Berend, Mirza, Naheed R.
Publicado 2012

Metabolic and hepatic effects of liraglutide, obeticholic acid and elafibranor in diet-induced obese mouse models of biopsy-confirmed nonalcoholic steatohepatitis

por Tølbøl, Kirstine S, Kristiansen, Maria NB, Hansen, Henrik H, Veidal, Sanne S, Rigbolt, Kristoffer TG, Gillum, Matthew P, Jelsing, Jacob, Vrang, Niels, Feigh, Michael
Publicado 2018

Characterization of combined linagliptin and Y2R agonist treatment in diet-induced obese mice

por Hansen, Henrik H., Grønlund, Rikke V., Baader-Pagler, Tamara, Haebel, Peter, Tammen, Harald, Larsen, Leif Kongskov, Jelsing, Jacob, Vrang, Niels, Klein, Thomas
Publicado 2021

The GLP-1 Receptor Agonist Liraglutide Improves Memory Function and Increases Hippocampal CA1 Neuronal Numbers in a Senescence-Accelerated Mouse Model of Alzheimer’s Disease

por Hansen, Henrik H., Fabricius, Katrine, Barkholt, Pernille, Niehoff, Michael L., Morley, John E., Jelsing, Jacob, Pyke, Charles, Knudsen, Lotte Bjerre, Farr, Susan A., Vrang, Niels
Publicado 2015

Long-Term Treatment with Liraglutide, a Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist, Has No Effect on β-Amyloid Plaque Load in Two Transgenic APP/PS1 Mouse Models of Alzheimer...

por Hansen, Henrik H., Fabricius, Katrine, Barkholt, Pernille, Kongsbak-Wismann, Pernille, Schlumberger, Chantal, Jelsing, Jacob, Terwel, Dick, Termont, Annelies, Pyke, Charles, Knudsen, Lotte Bjerre, Vrang, Niels
Publicado 2016

Nephroprotective Effects of Semaglutide as Mono- and Combination Treatment with Lisinopril in a Mouse Model of Hypertension-Accelerated Diabetic Kidney Disease

por Dalbøge, Louise S., Christensen, Michael, Madsen, Martin Rønn, Secher, Thomas, Endlich, Nicole, Drenic’, Vedran, Manresa-Arraut, Alba, Hansen, Henrik H., Rune, Ida, Fink, Lisbeth N., Østergaard, Mette V.
Publicado 2022

INT-767 improves histopathological features in a diet-induced ob/ob mouse model of biopsy-confirmed non-alcoholic steatohepatitis

por Roth, Jonathan D, Feigh, Michael, Veidal, Sanne S, Fensholdt, Louise KD, Rigbolt, Kristoffer T, Hansen, Henrik H, Chen, Li C, Petitjean, Mathieu, Friley, Weslyn, Vrang, Niels, Jelsing, Jacob, Young, Mark
Publicado 2018

Disease Progression and Pharmacological Intervention in a Nutrient-Deficient Rat Model of Nonalcoholic Steatohepatitis

por Tølbøl, Kirstine S., Stierstorfer, Birgit, Rippmann, Jörg F., Veidal, Sanne S., Rigbolt, Kristoffer T. G., Schönberger, Tanja, Gillum, Matthew P., Hansen, Henrik H., Vrang, Niels, Jelsing, Jacob, Feigh, Michael, Broermann, Andre
Publicado 2018

Lipidated PrRP31 metabolites are long acting dual GPR10 and NPFF2 receptor agonists with potent body weight lowering effect

por Alexopoulou, Flora, Bech, Esben Matzen, Pedersen, Søren Ljungberg, Thorbek, Ditte Dencker, Leurs, Ulrike, Rudkjær, Lise Christine Biehl, Fosgerau, Keld, Hansen, Henrik H., Vrang, Niels, Jelsing, Jacob, Elster, Lisbeth
Publicado 2022

Metabolic and gut microbiome changes following GLP-1 or dual GLP-1/GLP-2 receptor agonist treatment in diet-induced obese mice

por Madsen, Mette Simone Aae, Holm, Jacob Bak, Pallejà, Albert, Wismann, Pernille, Fabricius, Katrine, Rigbolt, Kristoffer, Mikkelsen, Martin, Sommer, Morten, Jelsing, Jacob, Nielsen, Henrik Bjørn, Vrang, Niels, Hansen, Henrik H.
Publicado 2019

Whole-brain activation signatures of weight-lowering drugs

por Hansen, Henrik H., Perens, Johanna, Roostalu, Urmas, Skytte, Jacob Lercke, Salinas, Casper Gravesen, Barkholt, Pernille, Thorbek, Ditte Dencker, Rigbolt, Kristoffer T.G., Vrang, Niels, Jelsing, Jacob, Hecksher-Sørensen, Jacob
Publicado 2021

Combined obeticholic acid and elafibranor treatment promotes additive liver histological improvements in a diet-induced ob/ob mouse model of biopsy-confirmed NASH

por Roth, Jonathan D., Veidal, Sanne S., Fensholdt, Louise K. D., Rigbolt, Kristoffer T. G., Papazyan, Romeo, Nielsen, Jens Christian, Feigh, Michael, Vrang, Niels, Young, Mark, Jelsing, Jacob, Adorini, Luciano, Hansen, Henrik H.
Publicado 2019

Global transcriptome analysis of rat hypothalamic arcuate nucleus demonstrates reversal of hypothalamic gliosis following surgically and diet induced weight loss

por Barkholt, Pernille, Rigbolt, Kristoffer T. G., Falkenhahn, Mechthilde, Hübschle, Thomas, Schwahn, Uwe, Fernandez-Cachon, Maria Luisa, Schmidt, Thorsten, Theis, Stefan, Hansen, Henrik H., Hay-Schmidt, Anders, Pedersen, Philip J., Vrang, Niels, Jelsing, Jacob
Publicado 2019

In Vitro and In Vivo Characterization of Dibenzothiophene Derivatives [(125)I]Iodo-ASEM and [(18)F]ASEM as Radiotracers of Homo- and Heteromeric α7 Nicotinic Acetylcholine Receptor...

por Donat, Cornelius K., Hansen, Henrik H., Hansen, Hanne D., Mease, Ronnie C., Horti, Andrew G., Pomper, Martin G., L’Estrade, Elina T., Herth, Matthias M., Peters, Dan, Knudsen, Gitte M., Mikkelsen, Jens D.
Publicado 2020

Quantitative whole-brain 3D imaging of tyrosine hydroxylase-labeled neuron architecture in the mouse MPTP model of Parkinson's disease

por Roostalu, Urmas, Salinas, Casper B. G., Thorbek, Ditte D., Skytte, Jacob L., Fabricius, Katrine, Barkholt, Pernille, John, Linu M., Jurtz, Vanessa Isabell, Knudsen, Lotte Bjerre, Jelsing, Jacob, Vrang, Niels, Hansen, Henrik H., Hecksher-Sørensen, Jacob
Publicado 2019

Effect of captopril on post-infarction remodelling visualized by light sheet microscopy and echocardiography

por Roostalu, Urmas, Thisted, Louise, Skytte, Jacob Lercke, Salinas, Casper Gravesen, Pedersen, Philip Juhl, Hecksher-Sørensen, Jacob, Rolin, Bidda, Hansen, Henrik H., MacKrell, James G., Christie, Robert M., Vrang, Niels, Jelsing, Jacob, Zois, Nora Elisabeth
Publicado 2021

Hepatoprotective effects of semaglutide, lanifibranor and dietary intervention in the GAN diet‐induced obese and biopsy‐confirmed mouse model of NASH

por Møllerhøj, Mathias B., Veidal, Sanne S., Thrane, Kirstine Tølbøl, Oró, Denise, Overgaard, Agnete, Salinas, Casper Gravesen, Madsen, Martin Rønn, Pfisterer, Larissa, Vyberg, Mogens, Simon, Eric, Broermann, Andre, Vrang, Niels, Jelsing, Jacob, Feigh, Michael, Hansen, Henrik H.
Publicado 2022