Structural Mechanism of ER Retrieval of MHC Class I by Cowpox

por McCoy, William H., Wang, Xiaoli, Yokoyama, Wayne M., Hansen, Ted H., Fremont, Daved H.
Publicado 2012

Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3

por Wang, Xiaoli, Herr, Roger A., Chua, Wei-Jen, Lybarger, Lonnie, Wiertz, Emmanuel J.H.J., Hansen, Ted H.
Publicado 2007

Ube2j2 ubiquitinates hydroxylated amino acids on ER-associated degradation substrates

por Wang, Xiaoli, Herr, Roger A., Rabelink, Martijn, Hoeben, Rob C., Wiertz, Emmanuel J.H.J., Hansen, Ted H.
Publicado 2009

MR1 uses an endocytic pathway to activate mucosal-associated invariant T cells

por Huang, Shouxiong, Gilfillan, Susan, Kim, Sojung, Thompson, Bruce, Wang, Xiaoli, Sant, Andrea J., Fremont, Daved H., Lantz, Olivier, Hansen, Ted H.
Publicado 2008

MAIT Cell Recognition of MR1 on Bacterially Infected and Uninfected Cells

por Young, Mary H., U’Ren, Lance, Huang, Shouxiong, Mallevaey, Thierry, Scott-Browne, James, Crawford, Frances, Lantz, Olivier, Hansen, Ted H., Kappler, John, Marrack, Philippa, Gapin, Laurent
Publicado 2013

CD161(++)CD8(+) T cells, including the MAIT cell subset, are specifically activated by IL-12+IL-18 in a TCR-independent manner

por Ussher, James E, Bilton, Matthew, Attwod, Emma, Shadwell, Jonathan, Richardson, Rachel, de Lara, Catherine, Mettke, Elisabeth, Kurioka, Ayako, Hansen, Ted H, Klenerman, Paul, Willberg, Christian B
Publicado 2014

TLR signaling in human antigen‐presenting cells regulates MR1‐dependent activation of MAIT cells

por Ussher, James E., van Wilgenburg, Bonnie, Hannaway, Rachel F., Ruustal, Kerstin, Phalora, Prabhjeet, Kurioka, Ayako, Hansen, Ted H., Willberg, Christian B., Phillips, Rodney E., Klenerman, Paul
Publicado 2016

Cancer Genome Sequencing and Its Implications for Personalized Cancer Vaccines

por Li, Lijin, Goedegebuure, Peter, Mardis, Elaine R., Ellis, Matthew J.C., Zhang, Xiuli, Herndon, John M., Fleming, Timothy P., Carreno, Beatriz M., Hansen, Ted H., Gillanders, William E.
Publicado 2011

Incorporation of Porcine Adenovirus 4 Fiber Protein Enhances Infectivity of Adenovirus Vector on Dendritic Cells: Implications for Immune-Mediated Cancer Therapy

por Wilkinson-Ryan, Ivy, Kim, Julius, Kim, Sojung, Ak, Ferhat, Dodson, Lindzy, Colonna, Marco, Powell, Matthew, Mutch, David, Spitzer, Dirk, Hansen, Ted, Goedegebuure, Simon P., Curiel, David, Hawkins, William
Publicado 2015

Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor

por Reantragoon, Rangsima, Kjer-Nielsen, Lars, Patel, Onisha, Chen, Zhenjun, Illing, Patricia T., Bhati, Mugdha, Kostenko, Lyudmila, Bharadwaj, Mandvi, Meehan, Bronwyn, Hansen, Ted H., Godfrey, Dale I., Rossjohn, Jamie, McCluskey, James
Publicado 2012

A herpesvirus encoded Qa-1 mimic inhibits natural killer cell cytotoxicity through CD94/NKG2A receptor engagement

por Wang, Xiaoli, Piersma, Sytse J, Nelson, Christopher A, Dai, Ya-Nan, Christensen, Ted, Lazear, Eric, Yang, Liping, Sluijter, Marjolein, van Hall, Thorbald, Hansen, Ted H, Yokoyama, Wayne M, Fremont, Daved H
Publicado 2018

MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage

por Gold, Marielle C., McLaren, James E., Reistetter, Joseph A., Smyk-Pearson, Sue, Ladell, Kristin, Swarbrick, Gwendolyn M., Yu, Yik Y.L., Hansen, Ted H., Lund, Ole, Nielsen, Morten, Gerritsen, Bram, Kesmir, Can, Miles, John J., Lewinsohn, Deborah A., Price, David A., Lewinsohn, David M.
Publicado 2014

Human Mucosal Associated Invariant T Cells Detect Bacterially Infected Cells

por Gold, Marielle C., Cerri, Stefania, Smyk-Pearson, Susan, Cansler, Meghan E., Vogt, Todd M., Delepine, Jacob, Winata, Ervina, Swarbrick, Gwendolyn M., Chua, Wei-Jen, Yu, Yik Y. L., Lantz, Olivier, Cook, Matthew S., Null, Megan D., Jacoby, David B., Harriff, Melanie J., Lewinsohn, Deborah A., Hansen, Ted H., Lewinsohn, David M.
Publicado 2010

Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells

por Reantragoon, Rangsima, Corbett, Alexandra J., Sakala, Isaac G., Gherardin, Nicholas A., Furness, John B., Chen, Zhenjun, Eckle, Sidonia B.G., Uldrich, Adam P., Birkinshaw, Richard W., Patel, Onisha, Kostenko, Lyudmila, Meehan, Bronwyn, Kedzierska, Katherine, Liu, Ligong, Fairlie, David P., Hansen, Ted H., Godfrey, Dale I., Rossjohn, Jamie, McCluskey, James, Kjer-Nielsen, Lars
Publicado 2013

Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation

por Li, Lijin, Zhang, Xiuli, Wang, Xiaoli, Kim, Samuel W., Herndon, John M., Becker-Hapak, Michelle K., Carreno, Beatriz M., Myers, Nancy B., Sturmoski, Mark A., McLellan, Michael D., Miller, Christopher A., Johanns, Tanner M., Tan, Benjamin R., Dunn, Gavin P., Fleming, Timothy P., Hansen, Ted H., Goedegebuure, S. Peter, Gillanders, William E.
Publicado 2021