mRNA trans‐splicing in gene therapy for genetic diseases

por Berger, Adeline, Maire, Séverine, Gaillard, Marie‐Claude, Sahel, José‐Alain, Hantraye, Philippe, Bemelmans, Alexis‐Pierre
Publicado 2016

Normal Aging Modulates the Neurotoxicity of Mutant Huntingtin

por Diguet, Elsa, Petit, Fanny, Escartin, Carole, Cambon, Karine, Bizat, Nicolas, Dufour, Noëlle, Hantraye, Philippe, Déglon, Nicole, Brouillet, Emmanuel
Publicado 2009

Differential Dopamine Receptor Occupancy Underlies L-DOPA-Induced Dyskinesia in a Rat Model of Parkinson's Disease

por Sahin, Gurdal, Thompson, Lachlan H., Lavisse, Sonia, Ozgur, Merve, Rbah-Vidal, Latifa, Dollé, Frédéric, Hantraye, Philippe, Kirik, Deniz
Publicado 2014

Automated Individualization of Size-Varying and Touching Neurons in Macaque Cerebral Microscopic Images

por You, Zhenzhen, Balbastre, Yaël, Bouvier, Clément, Hérard, Anne-Sophie, Gipchtein, Pauline, Hantraye, Philippe, Jan, Caroline, Souedet, Nicolas, Delzescaux, Thierry
Publicado 2019

Comparative test-retest variability of outcome parameters derived from brain [(18)F]FDG PET studies in non-human primates

por Goutal, Sébastien, Tournier, Nicolas, Guillermier, Martine, Van Camp, Nadja, Barret, Olivier, Gaudin, Mylène, Bottlaender, Michel, Hantraye, Philippe, Lavisse, Sonia
Publicado 2020

miRNA profile is altered in a modified EAE mouse model of multiple sclerosis featuring cortical lesions

por Orefice, Nicola S, Guillemot-Legris, Owein, Capasso, Rosanna, Bottemanne, Pauline, Hantraye, Philippe, Caraglia, Michele, Orefice, Giuseppe, Alhouayek, Mireille, Muccioli, Giulio G
Publicado 2020

Dopamine determines the vulnerability of striatal neurons to the N-terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II

por Benchoua, Alexandra, Trioulier, Yaël, Diguet, Elsa, Malgorn, Carole, Gaillard, Marie-Claude, Dufour, Noelle, Elalouf, Jean-Marc, Krajewski, Stan, Hantraye, Philippe, Déglon, Nicole, Brouillet, Emmanuel
Publicado 2008

In Vivo Cross-sectional Characterization of Cerebral Alterations Induced by Intracerebroventricular Administration of Streptozotocin

por Kraska, Audrey, Santin, Mathieu D., Dorieux, Olène, Joseph-Mathurin, Nelly, Bourrin, Emmanuel, Petit, Fanny, Jan, Caroline, Chaigneau, Marion, Hantraye, Philippe, Lestage, Pierre, Dhenain, Marc
Publicado 2012

Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson’s Disease

por Grealish, Shane, Diguet, Elsa, Kirkeby, Agnete, Mattsson, Bengt, Heuer, Andreas, Bramoulle, Yann, Van Camp, Nadja, Perrier, Anselme L., Hantraye, Philippe, Björklund, Anders, Parmar, Malin
Publicado 2014

Real-Time Monitoring of Exosome Enveloped-AAV Spreading by Endomicroscopy Approach: A New Tool for Gene Delivery in the Brain

por Orefice, Nicola Salvatore, Souchet, Benoît, Braudeau, Jérôme, Alves, Sandro, Piguet, Françoise, Collaud, Fanny, Ronzitti, Giuseppe, Tada, Satoru, Hantraye, Philippe, Mingozzi, Federico, Ducongé, Frédéric, Cartier, Nathalie
Publicado 2019

The pharmacokinetics of [(18)F]UCB-H revisited in the healthy non-human primate brain

por Goutal, Sébastien, Guillermier, Martine, Becker, Guillaume, Gaudin, Mylène, Bramoullé, Yann, Luxen, André, Lemaire, Christian, Plenevaux, Alain, Salmon, Eric, Hantraye, Philippe, Barret, Olivier, Van Camp, Nadja
Publicado 2021

Allele-Specific RNA Silencing of Mutant Ataxin-3 Mediates Neuroprotection in a Rat Model of Machado-Joseph Disease

por Alves, Sandro, Nascimento-Ferreira, Isabel, Auregan, Gwennaëlle, Hassig, Raymonde, Dufour, Noëlle, Brouillet, Emmanuel, Pedroso de Lima, Maria C., Hantraye, Philippe, Pereira de Almeida, Luís, Déglon, Nicole
Publicado 2008

Clustering of Tau fibrils impairs the synaptic composition of α3‐Na(+)/K(+)‐ATPase and AMPA receptors

por Shrivastava, Amulya Nidhi, Redeker, Virginie, Pieri, Laura, Bousset, Luc, Renner, Marianne, Madiona, Karine, Mailhes‐Hamon, Caroline, Coens, Audrey, Buée, Luc, Hantraye, Philippe, Triller, Antoine, Melki, Ronald
Publicado 2019

MHC matching fails to prevent long-term rejection of iPSC-derived neurons in non-human primates

por Aron Badin, Romina, Bugi, Aurore, Williams, Susannah, Vadori, Marta, Michael, Marie, Jan, Caroline, Nassi, Alberto, Lecourtois, Sophie, Blancher, Antoine, Cozzi, Emanuele, Hantraye, Philippe, Perrier, Anselme L.
Publicado 2019

In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects

por Faideau, Mathilde, Kim, Jinho, Cormier, Kerry, Gilmore, Richard, Welch, Mackenzie, Auregan, Gwennaelle, Dufour, Noelle, Guillermier, Martine, Brouillet, Emmanuel, Hantraye, Philippe, Déglon, Nicole, Ferrante, Robert J., Bonvento, Gilles
Publicado 2010

Neocortical morphometry in Huntington's disease: Indication of the coexistence of abnormal neurodevelopmental and neurodegenerative processes

por Mangin, Jean-Francois, Rivière, Denis, Duchesnay, Edouard, Cointepas, Yann, Gaura, Véronique, Verny, Christophe, Damier, Philippe, Krystkowiak, Pierre, Bachoud-Lévi, Anne-Catherine, Hantraye, Philippe, Remy, Philippe, Douaud, Gwenaëlle
Publicado 2020

Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies

por Dujardin, Simon, Lécolle, Katia, Caillierez, Raphaëlle, Bégard, Séverine, Zommer, Nadège, Lachaud, Cédrick, Carrier, Sébastien, Dufour, Noëlle, Aurégan, Gwennaëlle, Winderickx, Joris, Hantraye, Philippe, Déglon, Nicole, Colin, Morvane, Buée, Luc
Publicado 2014

A validation dataset for Macaque brain MRI segmentation

por Balbastre, Yaël, Rivière, Denis, Souedet, Nicolas, Fischer, Clara, Hérard, Anne-Sophie, Williams, Susannah, Vandenberghe, Michel E., Flament, Julien, Aron-Badin, Romina, Hantraye, Philippe, Mangin, Jean-François, Delzescaux, Thierry
Publicado 2017

Voxel-Based Statistical Analysis of 3D Immunostained Tissue Imaging

por Vandenberghe, Michel E., Souedet, Nicolas, Hérard, Anne-Sophie, Ayral, Anne-Marie, Letronne, Florent, Balbastre, Yaël, Sadouni, Elmahdi, Hantraye, Philippe, Dhenain, Marc, Frouin, Frédérique, Lambert, Jean-Charles, Delzescaux, Thierry
Publicado 2018

Experimental transfusion of variant CJD-infected blood reveals previously uncharacterised prion disorder in mice and macaque

por Comoy, Emmanuel E., Mikol, Jacqueline, Jaffré, Nina, Lebon, Vincent, Levavasseur, Etienne, Streichenberger, Nathalie, Sumian, Chryslain, Perret-Liaudet, Armand, Eloit, Marc, Andreoletti, Olivier, Haïk, Stéphane, Hantraye, Philippe, Deslys, Jean-Philippe
Publicado 2017