Impacts of the 2015 Heat Waves on Mortality in the Czech Republic—A Comparison with Previous Heat Waves

por Urban, Aleš, Hanzlíková, Hana, Kyselý, Jan, Plavcová, Eva
Publicado 2017

Multifunctional adaptor protein Daxx interacts with chromatin-remodelling ATPase Brg1

por Svadlenka, Jan, Brazina, Jan, Hanzlikova, Hana, Cermak, Lukas, Andera, Ladislav
Publicado 2015

Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin

por Hanzlikova, Hana, Gittens, William, Krejcikova, Katerina, Zeng, Zhihong, Caldecott, Keith W.
Publicado 2017

ATAD5 deficiency alters DNA damage metabolism and sensitizes cells to PARP inhibition

por Giovannini, Sara, Weller, Marie-Christine, Hanzlíková, Hana, Shiota, Tetsuya, Takeda, Shunichi, Jiricny, Josef
Publicado 2020

DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase

por Brazina, Jan, Svadlenka, Jan, Macurek, Libor, Andera, Ladislav, Hodny, Zdenek, Bartek, Jiri, Hanzlikova, Hana
Publicado 2015

The Importance of Poly(ADP-Ribose) Polymerase as a Sensor of Unligated Okazaki Fragments during DNA Replication

por Hanzlikova, Hana, Kalasova, Ilona, Demin, Annie A., Pennicott, Lewis E., Cihlarova, Zuzana, Caldecott, Keith W.
Publicado 2018

PARP inhibition impedes the maturation of nascent DNA strands during DNA replication

por Vaitsiankova, Alina, Burdova, Kamila, Sobol, Margarita, Gautam, Amit, Benada, Oldrich, Hanzlikova, Hana, Caldecott, Keith W.
Publicado 2022

Cells and Stripes: A novel quantitative photo-manipulation technique

por Mistrik, Martin, Vesela, Eva, Furst, Tomas, Hanzlikova, Hana, Frydrych, Ivo, Gursky, Jan, Majera, Dusana, Bartek, Jiri
Publicado 2016

Spatial Patterns of Heat-Related Cardiovascular Mortality in the Czech Republic

por Urban, Aleš, Burkart, Katrin, Kyselý, Jan, Schuster, Christian, Plavcová, Eva, Hanzlíková, Hana, Štěpánek, Petr, Lakes, Tobia
Publicado 2016

The XRCC1 phosphate-binding pocket binds poly (ADP-ribose) and is required for XRCC1 function

por Breslin, Claire, Hornyak, Peter, Ridley, Andrew, Rulten, Stuart L., Hanzlikova, Hana, Oliver, Antony W., Caldecott, Keith W.
Publicado 2015

Pathological mutations in PNKP trigger defects in DNA single-strand break repair but not DNA double-strand break repair

por Kalasova, Ilona, Hailstone, Richard, Bublitz, Janin, Bogantes, Jovel, Hofmann, Winfried, Leal, Alejandro, Hanzlikova, Hana, Caldecott, Keith W
Publicado 2020

Homozygous pathogenic variant in BRAT1 associated with nonprogressive cerebellar ataxia

por Mahjoub, Areej, Cihlarova, Zuzana, Tétreault, Martine, MacNeil, Lauren, Sondheimer, Neal, Caldecott, Keith W., Hanzlikova, Hana, Yoon, Grace
Publicado 2019

XRCC1 protects transcription from toxic PARP1 activity during DNA base excision repair

por Adamowicz, Marek, Hailstone, Richard, Demin, Annie A., Komulainen, Emilia, Hanzlikova, Hana, Brazina, Jan, Gautam, Amit, Wells, Sophie E., Caldecott, Keith W.
Publicado 2021

Novel PNKP mutations causing defective DNA strand break repair and PARP1 hyperactivity in MCSZ

por Kalasova, Ilona, Hanzlikova, Hana, Gupta, Neerja, Li, Yun, Altmüller, Janine, Reynolds, John J., Stewart, Grant S., Wollnik, Bernd, Yigit, Gökhan, Caldecott, Keith W.
Publicado 2019

BRAT1 links Integrator and defective RNA processing with neurodegeneration

por Cihlarova, Zuzana, Kubovciak, Jan, Sobol, Margarita, Krejcikova, Katerina, Sachova, Jana, Kolar, Michal, Stanek, David, Barinka, Cyril, Yoon, Grace, Caldecott, Keith W., Hanzlikova, Hana
Publicado 2022

Parp1 hyperactivity couples DNA breaks to aberrant neuronal calcium signalling and lethal seizures

por Komulainen, Emilia, Badman, Jack, Rey, Stephanie, Rulten, Stuart, Ju, Limei, Fennell, Kate, Kalasova, Ilona, Ilievova, Kristyna, McKinnon, Peter J, Hanzlikova, Hana, Staras, Kevin, Caldecott, Keith W
Publicado 2021

Pathogenic ARH3 mutations result in ADP-ribose chromatin scars during DNA strand break repair

por Hanzlikova, Hana, Prokhorova, Evgeniia, Krejcikova, Katerina, Cihlarova, Zuzana, Kalasova, Ilona, Kubovciak, Jan, Sachova, Jana, Hailstone, Richard, Brazina, Jan, Ghosh, Shereen, Cirak, Sebahattin, Gleeson, Joseph G., Ahel, Ivan, Caldecott, Keith W.
Publicado 2020

XRCC1 prevents toxic PARP1 trapping during DNA base excision repair

por Demin, Annie A., Hirota, Kouji, Tsuda, Masataka, Adamowicz, Marek, Hailstone, Richard, Brazina, Jan, Gittens, William, Kalasova, Ilona, Shao, Zhengping, Zha, Shan, Sasanuma, Hiroyuki, Hanzlikova, Hana, Takeda, Shunichi, Caldecott, Keith W.
Publicado 2021

XRCC1 Mutation is Associated with PARP1 Hyperactivation and Cerebellar Ataxia

por Hoch, Nicolas, Hanzlikova, Hana, Rulten, Stuart L., Tétreault, Martine, Koumulainen, Emilia, Ju, Limei, Hornyak, Peter, Zeng, Zhihong, Gittens, William, Rey, Stephanie, Staras, Kevin, Mancini, Grazia M.S., McKinnon, Peter J., Wang, Zhao-Qi, Wagner, Justin, Yoon, Grace, Caldecott, Keith W.
Publicado 2016