Lack of correlation between thymidylate synthase levels in primary colorectal tumours and subsequent response to chemotherapy.

por Findlay, M. P., Cunningham, D., Morgan, G., Clinton, S., Hardcastle, A., Aherne, G. W.
Publicado 1997

Deoxyuridine triphosphatase (dUTPase) expression and sensitivity to the thymidylate synthase (TS) inhibitorD9331

por Webley, S D, Hardcastle, A, Ladner, R D, Jackman, A L, Aherne, G W
Publicado 2000

Mechanisms of acquired resistance to the quinazoline thymidylate synthase inhibitor ZD1694 (Tomudex) in one mouse and three human cell lines.

por Jackman, A. L., Kelland, L. R., Kimbell, R., Brown, M., Gibson, W., Aherne, G. W., Hardcastle, A., Boyle, F. T.
Publicado 1995

A phase I pharmacokinetic and pharmacodynamic study of BGC9331 and carboplatin in relapsed gynaecological malignancies

por Benepal, T, Jackman, A, Pyle, L, Bate, S, Hardcastle, A, Aherne, W, Mitchell, F, Simmons, L, Ruddle, R, Raynaud, F, Gore, M
Publicado 2005

Economic inequalities in burden of illness, diagnosis and treatment of five long-term conditions in England: panel study

por Steel, N, Hardcastle, A C, Bachmann, M O, Richards, S H, Mounce, L T A, Clark, A, Lang, I, Melzer, D, Campbell, J
Publicado 2014

A Phase I study of the angiogenesis inhibitor SU5416 (semaxanib) in solid tumours, incorporating dynamic contrast MR pharmacodynamic end points

por O'Donnell, A, Padhani, A, Hayes, C, Kakkar, A J, Leach, M, Trigo, J M, Scurr, M, Raynaud, F, Phillips, S, Aherne, W, Hardcastle, A, Workman, P, Hannah, A, Judson, I
Publicado 2005