Higher-order phosphatase–substrate contacts terminate the integrated stress response

por Yan, Yahui, Harding, Heather P., Ron, David
Publicado 2021

Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response

por Lu, Phoebe D., Harding, Heather P., Ron, David
Publicado 2004

Uncoupling Proteostasis and Development in Vitro with a Small Molecule Inhibitor of the Pancreatic Endoplasmic Reticulum Kinase, PERK

por Harding, Heather P., Zyryanova, Alisa F., Ron, David
Publicado 2012

Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-γ

por Lin, Wensheng, Harding, Heather P., Ron, David, Popko, Brian
Publicado 2005

Feedback Inhibition of the Unfolded Protein Response by GADD34-Mediated Dephosphorylation of eIF2α

por Novoa, Isabel, Zeng, Huiqing, Harding, Heather P., Ron, David
Publicado 2001

Cargo receptor-assisted endoplasmic reticulum export of pathogenic α1-antitrypsin polymers

por Ordóñez, Adriana, Harding, Heather P., Marciniak, Stefan J., Ron, David
Publicado 2021

ERO1-β, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis

por Zito, Ester, Chin, King-Tung, Blais, Jaime, Harding, Heather P., Ron, David
Publicado 2010

ERO1-β, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis

por Zito, Ester, Chin, King-Tung, Blais, Jaime, Harding, Heather P., Ron, David
Publicado 2010

Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK

por Marciniak, Stefan J., Garcia-Bonilla, Lidia, Hu, Junjie, Harding, Heather P., Ron, David
Publicado 2006

Translation attenuation by PERK balances ER glycoprotein synthesis with lipid-linked oligosaccharide flux

por Shang, Jie, Gao, Ningguo, Kaufman, Randal J., Ron, David, Harding, Heather P., Lehrman, Mark A.
Publicado 2007

Inhibition of a constitutive translation initiation factor 2α phosphatase, CReP, promotes survival of stressed cells

por Jousse, Céline, Oyadomari, Seiichi, Novoa, Isabel, Lu, Phoebe, Zhang, Yuhong, Harding, Heather P., Ron, David
Publicado 2003

Paradoxical Sensitivity to an Integrated Stress Response Blocking Mutation in Vanishing White Matter Cells

por Sekine, Yusuke, Zyryanova, Alisa, Crespillo-Casado, Ana, Amin-Wetzel, Niko, Harding, Heather P., Ron, David
Publicado 2016

Dual role of the integrated stress response in medulloblastoma tumorigenesis

por Stone, Sarrabeth, Ho, Yeung, Li, Xiting, Jamison, Stephanie, Harding, Heather P., Ron, David, Lin, Wensheng
Publicado 2016

The ribosomal P-stalk couples amino acid starvation to GCN2 activation in mammalian cells

por Harding, Heather P, Ordonez, Adriana, Allen, Felicity, Parts, Leopold, Inglis, Alison J, Williams, Roger L, Ron, David
Publicado 2019

A J-Protein Co-chaperone Recruits BiP to Monomerize IRE1 and Repress the Unfolded Protein Response

por Amin-Wetzel, Niko, Saunders, Reuben A., Kamphuis, Maarten J., Rato, Claudia, Preissler, Steffen, Harding, Heather P., Ron, David
Publicado 2017

Intact protein folding in the glutathione-depleted endoplasmic reticulum implicates alternative protein thiol reductants

por Tsunoda, Satoshi, Avezov, Edward, Zyryanova, Alisa, Konno, Tasuku, Mendes-Silva, Leonardo, Pinho Melo, Eduardo, Harding, Heather P, Ron, David
Publicado 2014

Lifetime imaging of a fluorescent protein sensor reveals surprising stability of ER thiol redox

por Avezov, Edward, Cross, Benedict C.S., Kaminski Schierle, Gabriele S., Winters, Mikael, Harding, Heather P., Melo, Eduardo Pinho, Kaminski, Clemens F., Ron, David
Publicado 2013

Physiological modulation of BiP activity by trans-protomer engagement of the interdomain linker

por Preissler, Steffen, Chambers, Joseph E, Crespillo-Casado, Ana, Avezov, Edward, Miranda, Elena, Perez, Juan, Hendershot, Linda M, Harding, Heather P, Ron, David
Publicado 2015

A Method to Quantify FRET Stoichiometry with Phasor Plot Analysis and Acceptor Lifetime Ingrowth

por Chen, WeiYue, Avezov, Edward, Schlachter, Simon C., Gielen, Fabrice, Laine, Romain F., Harding, Heather P., Hollfelder, Florian, Ron, David, Kaminski, Clemens F.
Publicado 2015

G-actin provides substrate-specificity to eukaryotic initiation factor 2α holophosphatases

por Chen, Ruming, Rato, Cláudia, Yan, Yahui, Crespillo-Casado, Ana, Clarke, Hanna J, Harding, Heather P, Marciniak, Stefan J, Read, Randy J, Ron, David
Publicado 2015