The Birth of the Modern Era of Parkinson’s Disease Genetics

por Singleton, Andrew B., Hardy, John A., Gasser, Thomas
Publicado 2017

Genome Wide Assessment of Young Onset Parkinson’s Disease from Finland

por Hernandez, Dena G., Nalls, Michael A., Ylikotila, Pauli, Keller, Margaux, Hardy, John A., Majamaa, Kari, Singleton, Andrew B.
Publicado 2012

A blood-based gene expression and signaling pathway analysis to differentiate between high and low grade gliomas

por Ponnampalam, Stephen N., Kamaluddin, Nor Rizan, Zakaria, Zubaidah, Matheneswaran, Vickneswaran, Ganesan, Dharmendra, Haspani, Mohammed Saffari, Ryten, Mina, Hardy, John A.
Publicado 2017

Abrogation of LRRK2 dependent Rab10 phosphorylation with TLR4 activation and alterations in evoked cytokine release in immune cells

por Nazish, Iqra, Arber, Charles, Piers, Thomas M., Warner, Thomas T., Hardy, John A., Lewis, Patrick A., Pocock, Jennifer M., Bandopadhyay, Rina
Publicado 2021

Identification of Stk25 as a Genetic Modifier of Tau Phosphorylation in Dab1-Mutant Mice

por Matsuki, Tohru, Zaka, Mariam, Guerreiro, Rita, van der Brug, Marcel P., Cooper, Jonathan A., Cookson, Mark R., Hardy, John A., Howell, Brian W.
Publicado 2012

First effects of rising amyloid-β in transgenic mouse brain: synaptic transmission and gene expression

por Cummings, Damian M., Liu, Wenfei, Portelius, Erik, Bayram, Sevinç, Yasvoina, Marina, Ho, Sui-Hin, Smits, Hélène, Ali, Shabinah S., Steinberg, Rivka, Pegasiou, Chrysia-Maria, James, Owain T., Matarin, Mar, Richardson, Jill C., Zetterberg, Henrik, Blennow, Kaj, Hardy, John A., Salih, Dervis A., Edwards, Frances A.
Publicado 2015

Functional genomics provide key insights to improve the diagnostic yield of hereditary ataxia

por Chen, Zhongbo, Tucci, Arianna, Cipriani, Valentina, Gustavsson, Emil K, Ibañez, Kristina, Reynolds, Regina H, Zhang, David, Vestito, Letizia, García, Alejandro Cisterna, Sethi, Siddharth, Brenton, Jonathan W, García-Ruiz, Sonia, Fairbrother-Browne, Aine, Gil-Martinez, Ana-Luisa, Wood, Nick, Hardy, John A, Smedley, Damian, Houlden, Henry, Botía, Juan, Ryten, Mina
Publicado 2023

Multi-modality machine learning predicting Parkinson’s disease

por Makarious, Mary B., Leonard, Hampton L., Vitale, Dan, Iwaki, Hirotaka, Sargent, Lana, Dadu, Anant, Violich, Ivo, Hutchins, Elizabeth, Saffo, David, Bandres-Ciga, Sara, Kim, Jonggeol Jeff, Song, Yeajin, Maleknia, Melina, Bookman, Matt, Nojopranoto, Willy, Campbell, Roy H., Hashemi, Sayed Hadi, Botia, Juan A., Carter, John F., Craig, David W., Van Keuren-Jensen, Kendall, Morris, Huw R., Hardy, John A., Blauwendraat, Cornelis, Singleton, Andrew B., Faghri, Faraz, Nalls, Mike A.
Publicado 2022

The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target

por Petyuk, Vladislav A, Chang, Rui, Ramirez-Restrepo, Manuel, Beckmann, Noam D, Henrion, Marc Y R, Piehowski, Paul D, Zhu, Kuixi, Wang, Sven, Clarke, Jennifer, Huentelman, Matthew J, Xie, Fang, Andreev, Victor, Engel, Anzhelika, Guettoche, Toumy, Navarro, Loida, De Jager, Philip, Schneider, Julie A, Morris, Christopher M, McKeith, Ian G, Perry, Robert H, Lovestone, Simon, Woltjer, Randall L, Beach, Thomas G, Sue, Lucia I, Serrano, Geidy E, Lieberman, Andrew P, Albin, Roger L, Ferrer, Isidre, Mash, Deborah C, Hulette, Christine M, Ervin, John F, Reiman, Eric M, Hardy, John A, Bennett, David A, Schadt, Eric, Smith, Richard D, Myers, Amanda J
Publicado 2018

Genome-Wide Association Study reveals genetic risk underlying Parkinson’s disease

por Simon-Sanchez, Javier, Schulte, Claudia, Bras, Jose M, Sharma, Manu, Gibbs, J Raphael, Berg, Daniela, Paisan-Ruiz, Coro, Lichtner, Peter, Scholz, Sonja W, Hernandez, Dena G, Kruger, Rejko, Federoff, Monica, Klein, Christine, Goate, Alison, Perlmutter, Joel, Bonin, Michael, Nalls, Michael A, Illig, Thomas, Gieger, Christian, Houlden, Henry, Steffens, Michael, Okun, Michael S., Cookson, Mark, Foote, Kelly D, Fernandez, Hubert H, Traynor, Bryan J., Schreiber, Stefan, Arepalli, Sampath, Zonozi, Ryan, Gwinn, Katrina, van der Brug, Marcel, Lopez, Grisel, Chanock, Stephen J, Schatzkin, Arthur, Park, Yikyung, Hollenbeck, Albert, Gao, Jianjun, Huang, Xuemei, Wood, Nick W, Lorenz, Delia, Deuschl, Gunther, Chen, Honglei, Riess, Olaf, Hardy, John A, Singleton, Andrew B, Gasser, Thomas
Publicado 2009

A genome-wide association study in multiple system atrophy

por Sailer, Anna, Scholz, Sonja W., Nalls, Michael A., Schulte, Claudia, Federoff, Monica, Price, T. Ryan, Lees, Andrew, Ross, Owen A., Dickson, Dennis W., Mok, Kin, Mencacci, Niccolo E., Schottlaender, Lucia, Chelban, Viorica, Ling, Helen, O'Sullivan, Sean S., Wood, Nicholas W., Traynor, Bryan J., Ferrucci, Luigi, Federoff, Howard J., Mhyre, Timothy R., Morris, Huw R., Deuschl, Günther, Quinn, Niall, Widner, Hakan, Albanese, Alberto, Infante, Jon, Bhatia, Kailash P., Poewe, Werner, Oertel, Wolfgang, Höglinger, Günter U., Wüllner, Ullrich, Goldwurm, Stefano, Pellecchia, Maria Teresa, Ferreira, Joaquim, Tolosa, Eduardo, Bloem, Bastiaan R., Rascol, Olivier, Meissner, Wassilios G., Hardy, John A., Revesz, Tamas, Holton, Janice L., Gasser, Thomas, Wenning, Gregor K., Singleton, Andrew B., Houlden, Henry
Publicado 2016

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson’s disease

por Nalls, Mike A, Pankratz, Nathan, Lill, Christina M., Do, Chuong B, Hernandez, Dena G., Saad, Mohamad, DeStefano, Anita L., Kara, Eleanna, Bras, Jose, Sharma, Manu, Schulte, Claudia, Keller, Margaux F., Arepalli, Sampath, Letson, Christopher, Edsall, Connor, Stefansson, Hreinn, Liu, Xinmin, Pliner, Hannah, Lee, Joseph H., Cheng, Rong, Ikram, M. Arfan, Ioannidis, John P.A., Hadjigeorgiou, Georgios M., Bis, Joshua C., Martinez, Maria, Perlmutter, Joel S., Goate, Alison, Marder, Karen, Fiske, Brian, Sutherland, Margaret, Xiromerisiou, Georgia, Myers, Richard H., Clark, Lorraine N, Stefansson, Kari, Hardy, John A., Heutink, Peter, Chen, Honglei, Wood, Nicholas W., Houlden, Henry, Payami, Haydeh, Brice, Alexis, Scott, William K, Gasser, Thomas, Bertram, Lars, Eriksson, Nicholas, Foroud, Tatiana, Singleton, Andrew B.
Publicado 2014

Genome-wide structural variant analysis identifies risk loci for non-Alzheimer’s dementias

por Kaivola, Karri, Chia, Ruth, Ding, Jinhui, Rasheed, Memoona, Fujita, Masashi, Menon, Vilas, Walton, Ronald L., Collins, Ryan L., Billingsley, Kimberley, Brand, Harrison, Talkowski, Michael, Zhao, Xuefang, Dewan, Ramita, Stark, Ali, Ray, Anindita, Solaiman, Sultana, Alvarez Jerez, Pilar, Malik, Laksh, Dawson, Ted M., Rosenthal, Liana S., Albert, Marilyn S., Pletnikova, Olga, Troncoso, Juan C., Masellis, Mario, Keith, Julia, Black, Sandra E., Ferrucci, Luigi, Resnick, Susan M., Tanaka, Toshiko, Topol, Eric, Torkamani, Ali, Tienari, Pentti, Foroud, Tatiana M., Ghetti, Bernardino, Landers, John E., Ryten, Mina, Morris, Huw R., Hardy, John A., Mazzini, Letizia, D'Alfonso, Sandra, Moglia, Cristina, Calvo, Andrea, Serrano, Geidy E., Beach, Thomas G., Ferman, Tanis, Graff-Radford, Neill R., Boeve, Bradley F., Wszolek, Zbigniew K., Dickson, Dennis W., Chiò, Adriano, Bennett, David A., De Jager, Philip L., Ross, Owen A., Dalgard, Clifton L., Gibbs, J. Raphael, Traynor, Bryan J., Scholz, Sonja W.
Publicado 2023

Comprehensive Research Synopsis and Systematic Meta-Analyses in Parkinson's Disease Genetics: The PDGene Database

por Lill, Christina M., Roehr, Johannes T., McQueen, Matthew B., Kavvoura, Fotini K., Bagade, Sachin, Schjeide, Brit-Maren M., Schjeide, Leif M., Meissner, Esther, Zauft, Ute, Allen, Nicole C., Liu, Tian, Schilling, Marcel, Anderson, Kari J., Beecham, Gary, Berg, Daniela, Biernacka, Joanna M., Brice, Alexis, DeStefano, Anita L., Do, Chuong B., Eriksson, Nicholas, Factor, Stewart A., Farrer, Matthew J., Foroud, Tatiana, Gasser, Thomas, Hamza, Taye, Hardy, John A., Heutink, Peter, Hill-Burns, Erin M., Klein, Christine, Latourelle, Jeanne C., Maraganore, Demetrius M., Martin, Eden R., Martinez, Maria, Myers, Richard H., Nalls, Michael A., Pankratz, Nathan, Payami, Haydeh, Satake, Wataru, Scott, William K., Sharma, Manu, Singleton, Andrew B., Stefansson, Kari, Toda, Tatsushi, Tung, Joyce Y., Vance, Jeffery, Wood, Nick W., Zabetian, Cyrus P., Young, Peter, Tanzi, Rudolph E., Khoury, Muin J., Zipp, Frauke, Lehrach, Hans, Ioannidis, John P. A., Bertram, Lars
Publicado 2012

Creating the Pick’s disease International Consortium: Association study of MAPT H2 haplotype with risk of Pick’s disease

por Valentino, Rebecca R, Scotton, William J, Roemer, Shanu F, Lashley, Tammaryn, Heckman, Michael G, Shoai, Maryam, Martinez-Carrasco, Alejandro, Tamvaka, Nicole, Walton, Ronald L, Baker, Matthew C, Macpherson, Hannah L, Real, Raquel, Soto-Beasley, Alexandra I, Mok, Kin, Revesz, Tamas, Warner, Thomas T, Jaunmuktane, Zane, Boeve, Bradley F, Christopher, Elizabeth A, DeTure, Michael, Duara, Ranjan, Graff-Radford, Neill R, Josephs, Keith A, Knopman, David S, Koga, Shunsuke, Murray, Melissa E, Lyons, Kelly E, Pahwa, Rajesh, Parisi, Joseph E, Petersen, Ronald C, Whitwell, Jennifer, Grinberg, Lea T, Miller, Bruce, Schlereth, Athena, Seeley, William W, Spina, Salvatore, Grossman, Murray, Irwin, David J, Lee, Edward B, Suh, EunRan, Trojanowski, John Q, Van Deerlin, Vivianna M, Wolk, David A, Connors, Theresa R, Dooley, Patrick M, Frosch, Matthew P, Oakley, Derek H, Aldecoa, Iban, Balasa, Mircea, Gelpi, Ellen, Borrego-Écija, Sergi, de Eugenio Huélamo, Rosa Maria, Gascon-Bayarri, Jordi, Sánchez-Valle, Raquel, Sanz-Cartagena, Pilar, Piñol-Ripoll, Gerard, Molina-Porcel, Laura, Bigio, Eileen H, Flanagan, Margaret E, Gefen, Tamar, Rogalski, Emily J, Weintraub, Sandra, Redding-Ochoa, Javier, Chang, Koping, Troncoso, Juan C, Prokop, Stefan, Newell, Kathy L, Ghetti, Bernardino, Jones, Matthew, Richardson, Anna, Robinson, Andrew C, Roncaroli, Federico, Snowden, Julie, Allinson, Kieren, Green, Oliver, Rowe, James B, Singh, Poonam, Beach, Thomas G, Serrano, Geidy E, Flowers, Xena E, Goldman, James E, Heaps, Allison C, Leskinen, Sandra P, Teich, Andrew F, Black, Sandra E, Keith, Julia L, Masellis, Mario, Bodi, Istvan, King, Andrew, Sarraj, Safa-Al, Troakes, Claire, Halliday, Glenda M, Hodges, John R, Kril, Jillian J, Kwok, John B, Piguet, Olivier, Gearing, Marla, Arzberger, Thomas, Roeber, Sigrun, Attems, Johannes, Morris, Christopher M, Thomas, Alan J, Evers, Bret M., White, Charles L, Mechawar, Naguib, Sieben, Anne A, Cras, Patrick P, De Vil, Bart B, De Deyn, Peter Paul P.P., Duyckaerts, Charles, Le Ber, Isabelle, Seihean, Danielle, Turbant-Leclere, Sabrina, MacKenzie, Ian R, McLean, Catriona, Cykowski, Matthew D, Ervin, John F, Wang, Shih-Hsiu J, Graff, Caroline, Nennesmo, Inger, Nagra, Rashed M, Riehl, James, Kovacs, Gabor G, Giaccone, Giorgio, Nacmias, Benedetta, Neumann, Manuela, Ang, Lee-Cyn, Finger, Elizabeth C, Blauwendraat, Cornelis, Nalls, Mike A, Singleton, Andrew B, Vitale, Dan, Cunha, Cristina, Carvalho, Agostinho, Wszolek, Zbigniew K, Morris, Huw R, Rademakers, Rosa, Hardy, John A, Dickson, Dennis W, Rohrer, Jonathan D, Ross, Owen A
Publicado 2023

Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture

por Chia, Ruth, Sabir, Marya S., Bandres-Ciga, Sara, Saez-Atienzar, Sara, Reynolds, Regina H., Gustavsson, Emil, Walton, Ronald L., Ahmed, Sarah, Viollet, Coralie, Ding, Jinhui, Makarious, Mary B., Diez-Fairen, Monica, Portley, Makayla K., Shah, Zalak, Abramzon, Yevgeniya, Hernandez, Dena G., Blauwendraat, Cornelis, Stone, David J., Eicher, John, Parkkinen, Laura, Ansorge, Olaf, Clark, Lorraine, Honig, Lawrence S., Marder, Karen, Lemstra, Afina, St George-Hyslop, Peter, Londos, Elisabet, Morgan, Kevin, Lashley, Tammaryn, Warner, Thomas T., Jaunmuktane, Zane, Galasko, Douglas, Santana, Isabel, Tienari, Pentti J., Myllykangas, Liisa, Oinas, Minna, Cairns, Nigel J., Morris, John C., Halliday, Glenda M., Van Deerlin, Vivianna M., Trojanowski, John Q., Grassano, Maurizio, Calvo, Andrea, Mora, Gabriele, Canosa, Antonio, Floris, Gianluca, Bohannan, Ryan C., Brett, Francesca, Gan-Or, Ziv, Geiger, Joshua T., Moore, Anni, May, Patrick, Krüger, Rejko, Goldstein, David S., Lopez, Grisel, Tayebi, Nahid, Sidransky, Ellen, Norcliffe-Kaufmann, Lucy, Palma, Jose-Alberto, Kaufmann, Horacio, Shakkottai, Vikram G., Perkins, Matthew, Newell, Kathy L., Gasser, Thomas, Schulte, Claudia, Landi, Francesco, Salvi, Erika, Cusi, Daniele, Masliah, Eliezer, Kim, Ronald C., Caraway, Chad A., Monuki, Edwin S., Brunetti, Maura, Dawson, Ted M., Rosenthal, Liana S., Albert, Marilyn S., Pletnikova, Olga, Troncoso, Juan C., Flanagan, Margaret E., Mao, Qinwen, Bigio, Eileen H., Rodríguez-Rodríguez, Eloy, Infante, Jon, Lage, Carmen, González-Aramburu, Isabel, Sanchez-Juan, Pascual, Ghetti, Bernardino, Keith, Julia, Black, Sandra E., Masellis, Mario, Rogaeva, Ekaterina, Duyckaerts, Charles, Brice, Alexis, Lesage, Suzanne, Xiromerisiou, Georgia, Barrett, Matthew J., Tilley, Bension S., Gentleman, Steve, Logroscino, Giancarlo, Serrano, Geidy E., Beach, Thomas G., McKeith, Ian G., Thomas, Alan J., Attems, Johannes, Morris, Christopher M., Palmer, Laura, Love, Seth, Troakes, Claire, Al-Sarraj, Safa, Hodges, Angela K., Aarsland, Dag, Klein, Gregory, Kaiser, Scott M., Woltjer, Randy, Pastor, Pau, Bekris, Lynn M., Leverenz, James B., Besser, Lilah M., Kuzma, Amanda, Renton, Alan E., Goate, Alison, Bennett, David A., Scherzer, Clemens R., Morris, Huw R., Ferrari, Raffaele, Albani, Diego, Pickering-Brown, Stuart, Faber, Kelley, Kukull, Walter A., Morenas-Rodriguez, Estrella, Lleó, Alberto, Fortea, Juan, Alcolea, Daniel, Clarimon, Jordi, Nalls, Mike A., Ferrucci, Luigi, Resnick, Susan M., Tanaka, Toshiko, Foroud, Tatiana M., Graff-Radford, Neill R., Wszolek, Zbigniew K., Ferman, Tanis, Boeve, Bradley F., Hardy, John A., Topol, Eric J., Torkamani, Ali, Singleton, Andrew B., Ryten, Mina, Dickson, Dennis W., Chiò, Adriano, Ross, Owen A., Gibbs, J. Raphael, Dalgard, Clifton L., Traynor, Bryan J., Scholz, Sonja W.
Publicado 2021