The Interaction Between Lentiviral Integrase and LEDGF: Structural and Functional Insights

por Hare, Stephen, Cherepanov, Peter
Publicado 2009

The mechanism of retroviral integration through X-ray structures of its key intermediates

por Maertens, Goedele N., Hare, Stephen, Cherepanov, Peter
Publicado 2010

3′-Processing and strand transfer catalysed by retroviral integrase in crystallo

por Hare, Stephen, Maertens, Goedele N, Cherepanov, Peter
Publicado 2012

Pirates of the haemoglobin

por Akinbosede, Daniel, Chizea, Robert, Hare, Stephen A.
Publicado 2022

Retroviral intasome assembly and inhibition of DNA strand transfer

por Hare, Stephen, Gupta, Saumya Shree, Valkov, Eugene, Engelman, Alan, Cherepanov, Peter
Publicado 2010

Structures of the DfsB Protein Family Suggest a Cationic, Helical Sibling Lethal Factor Peptide

por Taylor, Jonathan D., Taylor, Gabrielle, Hare, Stephen A., Matthews, Steve J.
Publicado 2016

Structural Basis for Functional Tetramerization of Lentiviral Integrase

por Hare, Stephen, Di Nunzio, Francesca, Labeja, Alfred, Wang, Jimin, Engelman, Alan, Cherepanov, Peter
Publicado 2009

A Novel Co-Crystal Structure Affords the Design of Gain-of-Function Lentiviral Integrase Mutants in the Presence of Modified PSIP1/LEDGF/p75

por Hare, Stephen, Shun, Ming-Chieh, Gupta, Saumya Shree, Valkov, Eugene, Engelman, Alan, Cherepanov, Peter
Publicado 2009

Structural analysis of haemoglobin binding by HpuA from the Neisseriaceae family

por Wong, Chi T., Xu, Yingqi, Gupta, Akshari, Garnett, James A., Matthews, Steve J., Hare, Stephen A.
Publicado 2015

Brk/PTK6 and Involucrin Expression May Predict Breast Cancer Cell Responses to Vitamin D3

por Box, Carol, Pennington, Caroline, Hare, Stephen, Porter, Sarah, Edwards, Dylan, Eccles, Suzanne, Crompton, Mark, Harvey, Amanda
Publicado 2023

Functional and structural characterization of the integrase from the prototype foamy virus

por Valkov, Eugene, Gupta, Saumya Shree, Hare, Stephen, Helander, Anna, Roversi, Pietro, McClure, Myra, Cherepanov, Peter
Publicado 2009

Efficient transduction of LEDGF/p75 mutant cells by complementary gain-of-function HIV-1 integrase mutant viruses

por Wang, Hao, Shun, Ming-Chieh, Li, Xiang, Di Nunzio, Francesca, Hare, Stephen, Cherepanov, Peter, Engelman, Alan
Publicado 2014

A Salmonella Toxin Promotes Persister Formation through Acetylation of tRNA

por Cheverton, Angela M., Gollan, Bridget, Przydacz, Michal, Wong, Chi T., Mylona, Anastasia, Hare, Stephen A., Helaine, Sophie
Publicado 2016

Purification, crystallization and characterization of the Pseudomonas outer membrane protein FapF, a functional amyloid transporter

por Rouse, Sarah L., Hawthorne, Wlliam J., Lambert, Sebastian, Morgan, Marc L., Hare, Stephen A., Matthews, Stephen
Publicado 2016

An enhanced participant information leaflet and multimedia intervention to improve the quality of informed consent to a randomised clinical trial enrolling people living with HIV a...

por O’Sullivan, Lydia, Savinelli, Stefano, O’Hare, Stephen, Holden, Sinéad, McHugh, Ciara, Mallon, Patrick, Doran, Peter
Publicado 2022

Synthesis of a Thiazole Library via an Iridium-Catalyzed Sulfur Ylide Insertion Reaction

por Hassell-Hart, Storm, Speranzini, Elisa, Srikwanjai, Sirihathai, Hossack, Euan, Roe, S. Mark, Fearon, Daren, Akinbosede, Daniel, Hare, Stephen, Spencer, John
Publicado 2022

Activity of acetyltransferase toxins involved in Salmonella persister formation during macrophage infection

por Rycroft, Julian A., Gollan, Bridget, Grabe, Grzegorz J., Hall, Alexander, Cheverton, Angela M., Larrouy-Maumus, Gerald, Hare, Stephen A., Helaine, Sophie
Publicado 2018

Structural basis for retroviral integration into nucleosomes

por Maskell, Daniel P., Renault, Ludovic, Serrao, Erik, Lesbats, Paul, Matadeen, Rishi, Hare, Stephen, Lindemann, Dirk, Engelman, Alan N., Costa, Alessandro, Cherepanov, Peter
Publicado 2015

The Salmonella Effector SpvD Is a Cysteine Hydrolase with a Serovar-specific Polymorphism Influencing Catalytic Activity, Suppression of Immune Responses, and Bacterial Virulence

por Grabe, Grzegorz J., Zhang, Yue, Przydacz, Michal, Rolhion, Nathalie, Yang, Yi, Pruneda, Jonathan N., Komander, David, Holden, David W., Hare, Stephen A.
Publicado 2016

The development of novel LTA(4)H modulators to selectively target LTB(4) generation

por Low, Caroline M., Akthar, Samia, Patel, Dhiren F., Löser, Stephan, Wong, Chi-Tung, Jackson, Patricia L., Blalock, J. Edwin, Hare, Stephen A., Lloyd, Clare M., Snelgrove, Robert J.
Publicado 2017