A manual low-cost protein-crystallization plate jig for in situ diffraction in the home laboratory

por Hargreaves, David
Publicado 2012

A dynamically minimalist cognitive explanation of musical preference: is familiarity everything?

por Schubert, Emery, Hargreaves, David J., North, Adrian C.
Publicado 2014

Using isoelectric point to determine the pH for initial protein crystallization trials

por Kirkwood, Jobie, Hargreaves, David, O’Keefe, Simon, Wilson, Julie
Publicado 2015

Analysis of crystallization data in the Protein Data Bank

por Kirkwood, Jobie, Hargreaves, David, O’Keefe, Simon, Wilson, Julie
Publicado 2015

Predicting the Effect of Chemical Factors on the pH of Crystallization Trials

por Wilson, Julie, Ristic, Marko, Kirkwood, Jobie, Hargreaves, David, Newman, Janet
Publicado 2020

Not getting in too deep: A practical deep learning approach to routine crystallisation image classification

por Milne, Jamie, Qian, Chen, Hargreaves, David, Wang, Yinhai, Wilson, Julie
Publicado 2023

Antibody fragments structurally enable a drug-discovery campaign on the cancer target Mcl-1

por Luptak, Jakub, Bista, Michal, Fisher, David, Flavell, Liz, Gao, Ning, Wickson, Kate, Kazmirski, Steven L., Howard, Tina, Rawlins, Philip B., Hargreaves, David
Publicado 2019

Design of rigid protein–protein interaction inhibitors enables targeting of undruggable Mcl-1

por Hargreaves, David, Carbajo, Rodrigo J., Bodnarchuk, Michael S., Embrey, Kevin, Rawlins, Philip B., Packer, Martin, Degorce, Sébastien L., Hird, Alexander W., Johannes, Jeffrey W., Chiarparin, Elisabetta, Schade, Markus
Publicado 2023

Mechanistic insights into the rational design of masked antibodies

por Orozco, Carolina T., Bersellini, Manuela, Irving, Lorraine M., Howard, Wesley W., Hargreaves, David, Devine, Paul W. A., Siouve, Elise, Browne, Gareth J., Bond, Nicholas J., Phillips, Jonathan J., Ravn, Peter, Jackson, Sophie E.
Publicado 2022

Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia

por Tron, Adriana E., Belmonte, Matthew A., Adam, Ammar, Aquila, Brian M., Boise, Lawrence H., Chiarparin, Elisabetta, Cidado, Justin, Embrey, Kevin J., Gangl, Eric, Gibbons, Francis D., Gregory, Gareth P., Hargreaves, David, Hendricks, J. Adam, Johannes, Jeffrey W., Johnstone, Ricky W., Kazmirski, Steven L., Kettle, Jason G., Lamb, Michelle L., Matulis, Shannon M., Nooka, Ajay K., Packer, Martin J., Peng, Bo, Rawlins, Philip B., Robbins, Daniel W., Schuller, Alwin G., Su, Nancy, Yang, Wenzhan, Ye, Qing, Zheng, Xiaolan, Secrist, J. Paul, Clark, Edwin A., Wilson, David M., Fawell, Stephen E., Hird, Alexander W.
Publicado 2018