Frameworks for targeting RNA with small molecules

por Umuhire Juru, Aline, Hargrove, Amanda E.
Publicado 2020

Insights into the development of chemical probes for RNA

por Morgan, Brittany S, Forte, Jordan E, Hargrove, Amanda E
Publicado 2018

Recognizing the power of machine learning and other computational methods to accelerate progress in small molecule targeting of RNA

por Bagnolini, Greta, Luu, TinTin B., Hargrove, Amanda E.
Publicado 2023

Quantitative Structure–Activity Relationship (QSAR) Study Predicts Small-Molecule Binding to RNA Structure

por Cai, Zhengguo, Zafferani, Martina, Akande, Olanrewaju M., Hargrove, Amanda E.
Publicado 2022

RT-qPCR as a screening platform for mutational and small molecule impacts on structural stability of RNA tertiary structures

por Zafferani, Martina, Muralidharan, Dhanasheel, Montalvan, Nadeska I., Hargrove, Amanda E.
Publicado 2022

Probing Bioactive Chemical Space to Discover RNA-Targeted Small Molecules

por Wicks, Sarah L., Morgan, Brittany S., Wilson, Alexander W., Hargrove, Amanda E.
Publicado 2023

Regulation of MALAT1 triple helix stability and in vitro degradation by diphenylfurans

por Donlic, Anita, Zafferani, Martina, Padroni, Giacomo, Puri, Malavika, Hargrove, Amanda E
Publicado 2020

The discovery of antivirals and novel targets for SARS-CoV-2 and EV-A71

por Haddad, Christina, Tolbert, Blanton S., Hargrove, Amanda E., Brewer, Gary, Li, Mei-Ling
Publicado 2022

Characterization and Solubilization of Pyrrole–Imidazole Polyamide Aggregates

por Hargrove, Amanda E., Raskatov, Jevgenij A., Meier, Jordan L., Montgomery, David C., Dervan, Peter B.
Publicado 2012

Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide

por Hargrove, Amanda E., Martinez, Thomas F., Hare, Alissa A., Kurmis, Alexis A., Phillips, John W., Sud, Sudha, Pienta, Kenneth J, Dervan, Peter B.
Publicado 2015

IRES-targeting small molecule inhibits enterovirus 71 replication via allosteric stabilization of a ternary complex

por Davila-Calderon, Jesse, Patwardhan, Neeraj N., Chiu, Liang-Yuan, Sugarman, Andrew, Cai, Zhengguo, Penutmutchu, Srinivasa R., Li, Mei-Ling, Brewer, Gary, Hargrove, Amanda E., Tolbert, Blanton S.
Publicado 2020

High-resolution structure of stem-loop 4 from the 5′-UTR of SARS-CoV-2 solved by solution state NMR

por Vögele, Jennifer, Hymon, Daniel, Martins, Jason, Ferner, Jan, Jonker, Hendrik R A, Hargrove, Amanda E, Weigand, Julia E, Wacker, Anna, Schwalbe, Harald, Wöhnert, Jens, Duchardt-Ferner, Elke
Publicado 2023

Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures

por Martina, Zafferani, Christina, Haddad, Le, Luo, Jesse, Davila-Calderon, Liang, Yuan-Chiu, Christian, Shema Mugisha, Monaghan, Adeline G., Kennedy, Andrew A., Yesselman, Joseph D., Gifford, Robert R., Tai, Andrew W., Kutluay, Sebla B., Li, Mei-Ling, Brewer, Gary, Tolbert, Blanton S., Hargrove, Amanda E.
Publicado 2020

Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures

por Zafferani, Martina, Haddad, Christina, Luo, Le, Davila-Calderon, Jesse, Chiu, Liang-Yuan, Mugisha, Christian Shema, Monaghan, Adeline G., Kennedy, Andrew A., Yesselman, Joseph D., Gifford, Robert J., Tai, Andrew W., Kutluay, Sebla B., Li, Mei-Ling, Brewer, Gary, Tolbert, Blanton S., Hargrove, Amanda E.
Publicado 2021