Longevity as a matter of housekeeping

por Harkness, Troy A. A.
Publicado 2010

Activating the Anaphase Promoting Complex to Enhance Genomic Stability and Prolong Lifespan

por Harkness, Troy A. A.
Publicado 2018

The spatiotemporal dynamics of longevity-defining cellular processes and its modulation by genetic, dietary, and pharmacological anti-aging interventions

por Titorenko, Vladimir I., Harkness, Troy A. A.
Publicado 2012

Methods designed for the identification and characterization of in vitro and in vivo chromatin assembly mutants in Saccharomyces cerevisiae

por Harkness, Troy A. A., Arnason, Terra G., Legrand, Charmaine, Lone, Ashley
Publicado 2003

The Yeast Forkhead Transcription Factors Fkh1 and Fkh2 Regulate Lifespan and Stress Response Together with the Anaphase-Promoting Complex

por Postnikoff, Spike D. L., Malo, Mackenzie E., Wong, Berchman, Harkness, Troy A. A.
Publicado 2012

Mitotic degradation of yeast Fkh1 by the Anaphase Promoting Complex is required for normal longevity, genomic stability and stress resistance

por Malo, Mackenzie E., Postnikoff, Spike D.L., Arnason, Terra G., Harkness, Troy A.A.
Publicado 2016

Smc5/6 in the rDNA modulates lifespan independently of Fob1​

por Moradi‐Fard, Sarah, Mojumdar, Aditya, Chan, Megan, Harkness, Troy A.A., Cobb, Jennifer A.
Publicado 2021

Lithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cells

por Goldberg, Alexander A., Beach, Adam, Davies, Gerald F., Harkness, Troy A. A., LeBlanc, Andréa, Titorenko, Vladimir I.
Publicado 2011

A Genome Scale Screen for Mutants with Delayed Exit from Mitosis: Ire1-Independent Induction of Autophagy Integrates ER Homeostasis into Mitotic Lifespan

por Ghavidel, Ata, Baxi, Kunal, Ignatchenko, Vladimir, Prusinkiewicz, Martin, Arnason, Terra G., Kislinger, Thomas, Carvalho, Carlos E., Harkness, Troy A. A.
Publicado 2015

TFPI1 Mediates Resistance to Doxorubicin in Breast Cancer Cells by Inducing a Hypoxic-Like Response

por Davies, Gerald F., Berg, Arnie, Postnikoff, Spike D. L., Wilson, Heather L., Arnason, Terra G., Kusalik, Anthony, Harkness, Troy A. A.
Publicado 2014

The Nuclear Lamina: Protein Accumulation and Disease

por Almendáriz-Palacios, Carla, Gillespie, Zoe E., Janzen, Matthew, Martinez, Valeria, Bridger, Joanna M., Harkness, Troy A. A., Mousseau, Darrell D., Eskiw, Christopher H.
Publicado 2020

Activation of the Anaphase Promoting Complex Reverses Multiple Drug Resistant Cancer in a Canine Model of Multiple Drug Resistant Lymphoma

por Arnason, Terra G., MacDonald-Dickinson, Valerie, Gaunt, Matthew Casey, Davies, Gerald F., Lobanova, Liubov, Trost, Brett, Gillespie, Zoe E., Waldner, Matthew, Baldwin, Paige, Borrowman, Devon, Marwood, Hailey, Vizeacoumar, Frederick S., Vizeacoumar, Franco J., Eskiw, Christopher H., Kusalik, Anthony, Harkness, Troy A. A.
Publicado 2022