Pathology of HPV-Associated Head and Neck Carcinomas: Recent Data and Perspectives for the Development of Specific Tumor Markers

por Sastre-Garau, Xavier, Harlé, Alexandre
Publicado 2020

Detection of Microsatellite Instability: State of the Art and Future Applications in Circulating Tumour DNA (ctDNA)

por Gilson, Pauline, Merlin, Jean-Louis, Harlé, Alexandre
Publicado 2021

Deciphering Tumour Heterogeneity: From Tissue to Liquid Biopsy

por Gilson, Pauline, Merlin, Jean-Louis, Harlé, Alexandre
Publicado 2022

Somatic substitution signature as an innovative tool in lung cancer diagnosis

por Busca, Stéphane, Salleron, Julia, Boidot, Romain, Merlin, Jean-Louis, Harlé, Alexandre
Publicado 2019

SMAD4 and the TGFβ Pathway in Patients with Pancreatic Ductal Adenocarcinoma

por Dardare, Julie, Witz, Andréa, Merlin, Jean-Louis, Gilson, Pauline, Harlé, Alexandre
Publicado 2020

Emerging Roles of DDB2 in Cancer

por Gilson, Pauline, Drouot, Guillaume, Witz, Andréa, Merlin, Jean-Louis, Becuwe, Philippe, Harlé, Alexandre
Publicado 2019

ESR1 Gene Mutations and Liquid Biopsy in ER-Positive Breast Cancers: A Small Step Forward, a Giant Leap for Personalization of Endocrine Therapy?

por Betz, Margaux, Massard, Vincent, Gilson, Pauline, Witz, Andréa, Dardare, Julie, Harlé, Alexandre, Merlin, Jean-Louis
Publicado 2023

Dual Epigenetic Regulation of ERα36 Expression in Breast Cancer Cells

por Thiebaut, Charlène, Chesnel, Amand, Merlin, Jean-Louis, Chesnel, Maelle, Leroux, Agnès, Harlé, Alexandre, Dumond, Hélène
Publicado 2019

Evaluation of the Idylla ctEGFR mutation assay to detect EGFR mutations in plasma from patients with non-small cell lung cancers

por Gilson, Pauline, Saurel, Chloé, Salleron, Julia, Husson, Marie, Demange, Jessica, Merlin, Jean-Louis, Harlé, Alexandre
Publicado 2021

Epithelial to Mesenchymal Transition in Patients with Pancreatic Ductal Adenocarcinoma: State-of-the-Art and Therapeutic Opportunities

por Dardare, Julie, Witz, Andréa, Merlin, Jean-Louis, Bochnakian, Agathe, Toussaint, Paul, Gilson, Pauline, Harlé, Alexandre
Publicado 2021

Detection of BRAF Mutations Using a Fully Automated Platform and Comparison with High Resolution Melting, Real-Time Allele Specific Amplification, Immunohistochemistry and Next Gen...

por Harlé, Alexandre, Salleron, Julia, Franczak, Claire, Dubois, Cindy, Filhine-Tressarieu, Pierre, Leroux, Agnès, Merlin, Jean-Louis
Publicado 2016

Accelerated BRAF mutation analysis using a fully automated PCR platform improves the management of patients with metastatic melanoma

por Serre, Delphine, Salleron, Julia, Husson, Marie, Leroux, Agnès, Gilson, Pauline, Merlin, Jean-Louis, Geoffrois, Lionnel, Harlé, Alexandre
Publicado 2018

HPV insertional pattern as a personalized tumor marker for the optimized tumor diagnosis and follow-up of patients with HPV-associated carcinomas: a case report

por Harlé, Alexandre, Guillet, Julie, Thomas, Jacques, Demange, Jessica, Dolivet, Gilles, Peiffert, Didier, Leroux, Agnès, Sastre-Garau, Xavier
Publicado 2019

Beside P53 and PTEN: Identification of molecular alterations of the RAS/MAPK and PI3K/AKT signaling pathways in high-grade serous ovarian carcinomas to determine potential novel th...

por Chen, Shuhui, Cavazza, Elisa, Barlier, Catherine, Salleron, Julia, Filhine-Tresarrieu, Pierre, Gavoilles, Céline, Merlin, Jean-Louis, Harlé, Alexandre
Publicado 2016

Development of a Clinical–Biological Model to Assess Tumor Progression in Metastatic Pancreatic Cancer: Post Hoc Analysis of the PRODIGE4/ACCORD11 Trial

por Egea, Julie, Salleron, Julia, Gourgou, Sophie, Ayav, Ahmet, Laurent, Valérie, Juzyna, Béata, Harlé, Alexandre, Conroy, Thierry, Lambert, Aurélien
Publicado 2022

CRISPR/Cas9-mediated knock-in of BRCA1/2 mutations restores response to olaparib in pancreatic cancer cell lines

por Witz, Andréa, Dardare, Julie, Francois, Aurélie, Husson, Marie, Rouyer, Marie, Demange, Jessica, Merlin, Jean-Louis, Gilson, Pauline, Harlé, Alexandre
Publicado 2023

Integrated routine workflow using next-generation sequencing and a fully-automated platform for the detection of KRAS, NRAS and BRAF mutations in formalin-fixed paraffin embedded s...

por Franczak, Claire, Dubouis, Ludovic, Gilson, Pauline, Husson, Marie, Rouyer, Marie, Demange, Jessica, Leroux, Agnès, Merlin, Jean-Louis, Harlé, Alexandre
Publicado 2019

Uncommon mutational profiles of metastatic colorectal cancer detected during routine genotyping using next generation sequencing

por Franczak, Claire, Kandathil, Shaun M., Gilson, Pauline, Husson, Marie, Rouyer, Marie, Demange, Jessica, Leroux, Agnès, Merlin, Jean-Louis, Harlé, Alexandre
Publicado 2019

Evaluation of KRAS, NRAS and BRAF hotspot mutations detection for patients with metastatic colorectal cancer using direct DNA pipetting in a fully-automated platform and Next-Gener...

por Gilson, Pauline, Franczak, Claire, Dubouis, Ludovic, Husson, Marie, Rouyer, Marie, Demange, Jessica, Perceau, Marie, Leroux, Agnès, Merlin, Jean-Louis, Harlé, Alexandre
Publicado 2019

Evaluation of 3 molecular-based assays for microsatellite instability detection in formalin-fixed tissues of patients with endometrial and colorectal cancers

por Gilson, Pauline, Levy, Julien, Rouyer, Marie, Demange, Jessica, Husson, Marie, Bonnet, Céline, Salleron, Julia, Leroux, Agnès, Merlin, Jean-Louis, Harlé, Alexandre
Publicado 2020