Absence of the CXCR4 antagonist EPI-X4 from pharmaceutical human serum albumin preparations

por Gilg, Andrea, Harms, Mirja, Olari, Lia-Raluca, Urbanowitz, Ann-Kathrin, Bonig, Halvard, Münch, Jan
Publicado 2021

Utilization of Aminoguanidine Prevents Cytotoxic Effects of Semen

por Harms, Mirja, von Maltitz, Pascal, Groß, Rüdiger, Mayer, Benjamin, Deniz, Miriam, Müller, Janis, Münch, Jan
Publicado 2022

Inactivation and Environmental Stability of Zika Virus

por Müller, Janis A., Harms, Mirja, Schubert, Axel, Jansen, Stephanie, Michel, Detlef, Mertens, Thomas, Schmidt-Chanasit, Jonas, Münch, Jan
Publicado 2016

Storage-Dependent Generation of Potent Anti-ZIKV Activity in Human Breast Milk

por Conzelmann, Carina, Zou, Min, Groß, Rüdiger, Harms, Mirja, Röcker, Annika, Riedel, Christian U., Münch, Jan, Müller, Janis A.
Publicado 2019

Microtiter plate-based antibody-competition assay to determine binding affinities and plasma/blood stability of CXCR4 ligands

por Harms, Mirja, Gilg, Andrea, Ständker, Ludger, Beer, Ambros J., Mayer, Benjamin, Rasche, Volker, Gruber, Christian W., Münch, Jan
Publicado 2020

PPI-Affinity: A Web Tool for the Prediction and Optimization of Protein–Peptide and Protein–Protein Binding Affinity

por Romero-Molina, Sandra, Ruiz-Blanco, Yasser B., Mieres-Perez, Joel, Harms, Mirja, Münch, Jan, Ehrmann, Michael, Sanchez-Garcia, Elsa
Publicado 2022

Development of a New Class of CXCR4-Targeting Radioligands Based on the Endogenous Antagonist EPI-X4 for Oncological Applications

por Gaonkar, Raghuvir Haridas, Schmidt, Yannik Tim, Mansi, Rosalba, Almeida-Hernandez, Yasser, Sanchez-Garcia, Elsa, Harms, Mirja, Münch, Jan, Fani, Melpomeni
Publicado 2023

Targeting of CXCR4 by the Naturally Occurring CXCR4 Antagonist EPI-X4 in Waldenström’s Macroglobulinemia

por Kaiser, Lisa Marie, Harms, Mirja, Sauter, Daniel, Rawat, Vijay P. S., Glitscher, Mirco, Hildt, Eberhard, Tews, Daniel, Hunter, Zachary, Münch, Jan, Buske, Christian
Publicado 2021

Peptide Bispecifics Inhibiting HIV-1 Infection by an Orthogonal Chemical and Supramolecular Strategy

por Schauenburg, Dominik, Zech, Fabian, Heck, Astrid Johanna, von Maltitz, Pascal, Harms, Mirja, Führer, Siska, Alleva, Nico, Münch, Jan, Kuan, Seah Ling, Kirchhoff, Frank, Weil, Tanja
Publicado 2023

Development of a high-throughput colorimetric Zika virus infection assay

por Müller, Janis A., Harms, Mirja, Schubert, Axel, Mayer, Benjamin, Jansen, Stephanie, Herbeuval, Jean-Philippe, Michel, Detlef, Mertens, Thomas, Vapalahti, Olli, Schmidt-Chanasit, Jonas, Münch, Jan
Publicado 2017

Advanced EPI-X4 Derivatives Covalently Bind Human Serum Albumin Resulting in Prolonged Plasma Stability

por Rodríguez-Alfonso, Armando, Heck, Astrid, Ruiz-Blanco, Yasser Bruno, Gilg, Andrea, Ständker, Ludger, Kuan, Seah Ling, Weil, Tanja, Sanchez-Garcia, Elsa, Wiese, Sebastian, Münch, Jan, Harms, Mirja
Publicado 2022

Computational modeling and experimental validation of the EPI-X4/CXCR4 complex allows rational design of small peptide antagonists

por Sokkar, Pandian, Harms, Mirja, Stürzel, Christina, Gilg, Andrea, Kizilsavas, Gönül, Raasholm, Martina, Preising, Nico, Wagner, Manfred, Kirchhoff, Frank, Ständker, Ludger, Weidinger, Gilbert, Mayer, Benjamin, Münch, Jan, Sanchez-Garcia, Elsa
Publicado 2021

An optimized derivative of an endogenous CXCR4 antagonist prevents atopic dermatitis and airway inflammation

por Harms, Mirja, Habib, Monica M.W., Nemska, Simona, Nicolò, Antonella, Gilg, Andrea, Preising, Nico, Sokkar, Pandian, Carmignani, Sara, Raasholm, Martina, Weidinger, Gilbert, Kizilsavas, Gönül, Wagner, Manfred, Ständker, Ludger, Abadi, Ashraf H., Jumaa, Hassan, Kirchhoff, Frank, Frossard, Nelly, Sanchez-Garcia, Elsa, Münch, Jan
Publicado 2021

Natural cystatin C fragments inhibit GPR15-mediated HIV and SIV infection without interfering with GPR15L signaling

por Hayn, Manuel, Blötz, Andrea, Rodríguez, Armando, Vidal, Solange, Preising, Nico, Ständker, Ludger, Wiese, Sebastian, Stürzel, Christina M., Harms, Mirja, Gross, Rüdiger, Jung, Christoph, Kiene, Miriam, Jacob, Timo, Pöhlmann, Stefan, Forssmann, Wolf-Georg, Münch, Jan, Sparrer, Konstantin M. J., Seuwen, Klaus, Hahn, Beatrice H., Kirchhoff, Frank
Publicado 2021

Development of N-Terminally Modified Variants of the CXCR4-Antagonistic Peptide EPI-X4 for Enhanced Plasma Stability

por Harms, Mirja, Fabech Hansson, Rikke, Gilg, Andrea, Almeida-Hernández, Yasser, Löffler, Jessica, Rodríguez-Alfonso, Armando, Habib, Monica M. W., Albers, Dan, Ahmed, Nermin S., Abadi, Ashraf H., Winter, Gordon, Rasche, Volker, Beer, Ambros J., Weidinger, Gilbert, Preising, Nico, Ständker, Ludger, Wiese, Sebastian, Sanchez-Garcia, Elsa, Zelikin, Alexander N., Münch, Jan
Publicado 2023

The molecular tweezer CLR01 inhibits Ebola and Zika virus infection

por Röcker, Annika E., Müller, Janis A., Dietzel, Erik, Harms, Mirja, Krüger, Franziska, Heid, Christian, Sowislok, Andrea, Riber, Camilla Frich, Kupke, Alexandra, Lippold, Sina, von Einem, Jens, Beer, Judith, Knöll, Bernd, Becker, Stephan, Schmidt-Chanasit, Jonas, Otto, Markus, Vapalahti, Olli, Zelikin, Alexander N., Bitan, Gal, Schrader, Thomas, Münch, Jan
Publicado 2018

Control of TLR7-mediated type I IFN signaling in pDCs through CXCR4 engagement—A new target for lupus treatment

por Smith, Nikaïa, Rodero, Mathieu P., Bekaddour, Nassima, Bondet, Vincent, Ruiz-Blanco, Yasser B., Harms, Mirja, Mayer, Benjamin, Bader-Meunier, Brigitte, Quartier, Pierre, Bodemer, Christine, Baudouin, Véronique, Dieudonné, Yannick, Kirchhoff, Frank, Sanchez Garcia, Elsa, Charbit, Bruno, Leboulanger, Nicolas, Jahrsdörfer, Bernd, Richard, Yolande, Korganow, Anne-Sophie, Münch, Jan, Nisole, Sébastien, Duffy, Darragh, Herbeuval, Jean-Philippe
Publicado 2019

Semen inhibits Zika virus infection of cells and tissues from the anogenital region

por Müller, Janis A., Harms, Mirja, Krüger, Franziska, Groß, Rüdiger, Joas, Simone, Hayn, Manuel, Dietz, Andrea N., Lippold, Sina, von Einem, Jens, Schubert, Axel, Michel, Manuela, Mayer, Benjamin, Cortese, Mirko, Jang, Karen S., Sandi-Monroy, Nathallie, Deniz, Miriam, Ebner, Florian, Vapalahti, Olli, Otto, Markus, Bartenschlager, Ralf, Herbeuval, Jean-Philippe, Schmidt-Chanasit, Jonas, Roan, Nadia R., Münch, Jan
Publicado 2018

Spermine and spermidine bind CXCR4 and inhibit CXCR4- but not CCR5-tropic HIV-1 infection

por Harms, Mirja, Smith, Nikaïa, Han, Mingyu, Groß, Rüdiger, von Maltitz, Pascal, Stürzel, Christina, Ruiz-Blanco, Yasser B., Almeida-Hernández, Yasser, Rodriguez-Alfonso, Armando, Cathelin, Dominique, Caspar, Birgit, Tahar, Bouceba, Sayettat, Sophie, Bekaddour, Nassima, Vanshylla, Kanika, Kleipass, Franziska, Wiese, Sebastian, Ständker, Ludger, Klein, Florian, Lagane, Bernard, Boonen, Arnaud, Schols, Dominique, Benichou, Serge, Sanchez-Garcia, Elsa, Herbeuval, Jean-Philippe, Münch, Jan
Publicado 2023

Supramolecular Mechanism of Viral Envelope Disruption by Molecular Tweezers

por Weil, Tatjana, Groß, Rüdiger, Röcker, Annika, Bravo-Rodriguez, Kenny, Heid, Christian, Sowislok, Andrea, Le, My-Hue, Erwin, Nelli, Dwivedi, Mridula, Bart, Stephen M., Bates, Paul, Wettstein, Lukas, Müller, Janis A., Harms, Mirja, Sparrer, Konstantin, Ruiz-Blanco, Yasser B., Stürzel, Christina M., von Einem, Jens, Lippold, Sina, Read, Clarissa, Walther, Paul, Hebel, Marco, Kreppel, Florian, Klärner, Frank-Gerrit, Bitan, Gal, Ehrmann, Michael, Weil, Tanja, Winter, Roland, Schrader, Thomas, Shorter, James, Sanchez-Garcia, Elsa, Münch, Jan
Publicado 2020