Editorial: HIV and Cancer Immunotherapy: Similar Challenges and Converging Approaches

por Paiardini, Mirko, Dhodapkar, Kavita, Harper, Justin, Deeks, Steven G., Ahmed, Rafi
Publicado 2020

Crystal Structure of the Human Astrovirus Capsid Protein

por Toh, Yukimatsu, Harper, Justin, Dryden, Kelly A., Yeager, Mark, Arias, Carlos F., Méndez, Ernesto, Tao, Yizhi J.
Publicado 2016

Human astrovirus capsid protein releases a membrane lytic peptide upon trypsin maturation

por Ykema, Matthew, Ye, Kai, Xun, Meng, Harper, Justin, Betancourt-Solis, Miguel A., Arias, Carlos F., McNew, James A., Tao, Yizhi Jane
Publicado 2023

Timing of initiation of anti-retroviral therapy predicts post-treatment control of SIV replication

por Pinkevych, Mykola, Docken, Steffen S., Okoye, Afam A., Fennessey, Christine M., Del Prete, Gregory Q., Pino, Maria, Harper, Justin L., Betts, Michael R., Paiardini, Mirko, Keele, Brandon F., Davenport, Miles P.
Publicado 2023

A Tat/Rev Induced Limiting Dilution Assay to Measure Viral Reservoirs in Non-Human Primate Models of HIV Infection

por Frank, Ines, Acharya, Arpan, Routhu, Nanda K., Aravantinou, Meropi, Harper, Justin L., Maldonado, Stephanie, Sole Cigoli, Maria, Semova, Stanka, Mazel, Svetlana, Paiardini, Mirko, Derby, Nina, Byrareddy, Siddappa N., Martinelli, Elena
Publicado 2019

The loss of CCR6+ and CD161+ CD4+ T cell homeostasis contributes to disease progression in SIV-infected rhesus macaques

por McGary, Colleen S., Alvarez, Xavier, Harrington, Sean, Cervasi, Barbara, Ryan, Emily S., Iriele, Robin I., Paganini, Sara, Harper, Justin, Easley, Kirk, Silvestri, Guido, Ansari, Aftab A., Lichterfeld, Mathias, Micci, Luca, Paiardini, Mirko
Publicado 2017

IL-21 and IFNα therapy rescues terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques

por Harper, Justin, Huot, Nicolas, Micci, Luca, Tharp, Gregory, King, Colin, Rascle, Philippe, Shenvi, Neeta, Wang, Hong, Galardi, Cristin, Upadhyay, Amit A., Villinger, Francois, Lifson, Jeffrey, Silvestri, Guido, Easley, Kirk, Jacquelin, Beatrice, Bosinger, Steven, Müller-Trutwin, Michaela, Paiardini, Mirko
Publicado 2021

Fingolimod retains cytolytic T cells and limits T follicular helper cell infection in lymphoid sites of SIV persistence

por Pino, Maria, Paganini, Sara, Deleage, Claire, Padhan, Kartika, Harper, Justin L., King, Colin T., Micci, Luca, Cervasi, Barbara, Mudd, Joseph C., Gill, Kiran P., Jean, Sherrie M., Easley, Kirk, Silvestri, Guido, Estes, Jacob D., Petrovas, Constantinos, Lederman, Michael M., Paiardini, Mirko
Publicado 2019

The role of CD101-expressing CD4 T cells in HIV/SIV pathogenesis and persistence

por Strongin, Zachary, Hoang, Timothy N., Tharp, Gregory K., Rahmberg, Andrew R., Harper, Justin L., Nguyen, Kevin, Franchitti, Lavinia, Cervasi, Barbara, Lee, Max, Zhang, Zhan, Boritz, Eli A., Silvestri, Guido, Marconi, Vincent C., Bosinger, Steven E., Brenchley, Jason M., Kulpa, Deanna A., Paiardini, Mirko
Publicado 2022

SIV-induced terminally differentiated adaptive NK cells in lymph nodes associated with enhanced MHC-E restricted activity

por Huot, Nicolas, Rascle, Philippe, Petitdemange, Caroline, Contreras, Vanessa, Stürzel, Christina M., Baquero, Eduard, Harper, Justin L., Passaes, Caroline, Legendre, Rachel, Varet, Hugo, Madec, Yoann, Sauermann, Ulrike, Stahl-Hennig, Christiane, Nattermann, Jacob, Saez-Cirion, Asier, Le Grand, Roger, Keith Reeves, R., Paiardini, Mirko, Kirchhoff, Frank, Jacquelin, Beatrice, Müller-Trutwin, Michaela
Publicado 2021

Increased homeostatic cytokines and stability of HIV-infected memory CD4 T-cells identify individuals with suboptimal CD4 T-cell recovery on-ART

por Pino, Maria, Pereira Ribeiro, Susan, Pagliuzza, Amélie, Ghneim, Khader, Khan, Anum, Ryan, Emily, Harper, Justin L., King, Colin T., Welbourn, Sarah, Micci, Luca, Aldrete, Sol, Delman, Keith A., Stuart, Theron, Lowe, Michael, Brenchley, Jason M., Derdeyn, Cynthia A., Easley, Kirk, Sekaly, Rafick P., Chomont, Nicolas, Paiardini, Mirko, Marconi, Vincent C.
Publicado 2021

Limited impact of fingolimod treatment during the initial weeks of ART in SIV-infected rhesus macaques

por Pino, Maria, Pagliuzza, Amélie, Pampena, M. Betina, Deleage, Claire, Viox, Elise G., Nguyen, Kevin, Shim, Inbo, Zhang, Adam, Harper, Justin L., Samer, Sadia, King, Colin T., Cervasi, Barbara, Gill, Kiran P., Ehnert, Stephanie, Jean, Sherrie M., Freeman, Michael L., Lifson, Jeffrey D., Kulpa, Deanna, Betts, Michael R., Chomont, Nicolas, Lederman, Michael M., Paiardini, Mirko
Publicado 2022

Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated state in chronic SIV infection

por Lee, Michelle Y.-H., Upadhyay, Amit A., Walum, Hasse, Chan, Chi N., Dawoud, Reem A., Grech, Christine, Harper, Justin L., Karunakaran, Kirti A., Nelson, Sydney A., Mahar, Ernestine A., Goss, Kyndal L., Carnathan, Diane G., Cervasi, Barbara, Gill, Kiran, Tharp, Gregory K., Wonderlich, Elizabeth R., Velu, Vijayakumar, Barratt-Boyes, Simon M., Paiardini, Mirko, Silvestri, Guido, Estes, Jacob D., Bosinger, Steven E.
Publicado 2021

Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy

por Harper, Justin, Ribeiro, Susan P., Chan, Chi Ngai, Aid, Malika, Deleage, Claire, Micci, Luca, Pino, Maria, Cervasi, Barbara, Raghunathan, Gopalan, Rimmer, Eric, Ayanoglu, Gulesi, Wu, Guoxin, Shenvi, Neeta, Barnard, Richard J.O., Del Prete, Gregory Q., Busman-Sahay, Kathleen, Silvestri, Guido, Kulpa, Deanna A., Bosinger, Steven E., Easley, Kirk A., Howell, Bonnie J., Gorman, Dan, Hazuda, Daria J., Estes, Jacob D., Sekaly, Rafick-Pierre, Paiardini, Mirko
Publicado 2022

CD8(+) lymphocytes do not impact SIV reservoir establishment under ART

por Statzu, Maura, Jin, Wang, Fray, Emily J., Wong, Andrew Kam Ho, Kumar, Mithra R., Ferrer, Elizabeth, Docken, Steffen S., Pinkevych, Mykola, McBrien, Julia B., Fennessey, Christine M., Keele, Brandon F., Liang, Shan, Harper, Justin L., Mutascio, Simona, Franchitti, Lavinia, Wang, Hong, Cicetti, Davide, Bosinger, Steven E., Carnathan, Diane G., Vanderford, Thomas H., Margolis, David M., Garcia-Martinez, J. Victor, Chahroudi, Ann, Paiardini, Mirko, Siliciano, Janet, Davenport, Miles P., Kulpa, Deanna A., Siliciano, Robert S., Silvestri, Guido
Publicado 2023

TREM2(+) and interstitial-like macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques

por Upadhyay, Amit A., Viox, Elise G., Hoang, Timothy N., Boddapati, Arun K., Pino, Maria, Lee, Michelle Y.-H., Corry, Jacqueline, Strongin, Zachary, Cowan, David A., Beagle, Elizabeth N., Horton, Tristan R., Hamilton, Sydney, Aoued, Hadj, Harper, Justin L., Edwards, Christopher T., Nguyen, Kevin, Pellegrini, Kathryn L., Tharp, Gregory K., Piantadosi, Anne, Levit, Rebecca D., Amara, Rama R., Barratt-Boyes, Simon M., Ribeiro, Susan P., Sekaly, Rafick P., Vanderford, Thomas H., Schinazi, Raymond F., Paiardini, Mirko, Bosinger, Steven E.
Publicado 2023

Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques

por Hoang, Timothy N., Viox, Elise G., Upadhyay, Amit A., Strongin, Zachary, Tharp, Gregory K., Pino, Maria, Nchioua, Rayhane, Hirschenberger, Maximilian, Gagne, Matthew, Nguyen, Kevin, Harper, Justin L., Marciano, Shir, Boddapati, Arun K., Pellegrini, Kathryn L., Tisoncik-Go, Jennifer, Whitmore, Leanne S., Karunakaran, Kirti A., Roy, Melissa, Kirejczyk, Shannon, Curran, Elizabeth H., Wallace, Chelsea, Wood, Jennifer S., Connor-Stroud, Fawn, Kasturi, Sudhir P., Levit, Rebecca D., Gale, Michael, Vanderford, Thomas H., Silvestri, Guido, Busman-Sahay, Kathleen, Estes, Jacob D., Vaccari, Monica, Douek, Daniel C., Sparrer, Konstantin M.J., Kirchhoff, Frank, Johnson, R. Paul, Schreiber, Gideon, Bosinger, Steven E., Paiardini, Mirko
Publicado 2022

Baricitinib treatment resolves lower airway inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques

por Hoang, Timothy N., Pino, Maria, Boddapati, Arun K., Viox, Elise G., Starke, Carly E., Upadhyay, Amit A., Gumber, Sanjeev, Busman-Sahay, Kathleen, Strongin, Zachary, Harper, Justin L., Tharp, Gregory K., Pellegrini, Kathryn L., Kirejczyk, Shannon, Zandi, Keivan, Tao, Sijia, Horton, Tristan R., Beagle, Elizabeth N., Mahar, Ernestine A., Lee, Michelle YH, Cohen, Joyce, Jean, Sherrie M., Wood, Jennifer S., Connor-Stroud, Fawn, Stammen, Rachelle L., Delmas, Olivia M., Wang, Shelly, Cooney, Kimberly A., Sayegh, Michael N., Wang, Lanfang, Weiskopf, Daniela, Filev, Peter D., Waggoner, Jesse, Piantadosi, Anne, Kasturi, Sudhir P., Al-Shakhshir, Hilmi, Ribeiro, Susan P., Sekaly, Rafick P., Levit, Rebecca D., Estes, Jacob D., Vanderford, Thomas H., Schinazi, Raymond F., Bosinger, Steven E., Paiardini, Mirko
Publicado 2020

Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques

por Hoang, Timothy N., Pino, Maria, Boddapati, Arun K., Viox, Elise G., Starke, Carly E., Upadhyay, Amit A., Gumber, Sanjeev, Nekorchuk, Michael, Busman-Sahay, Kathleen, Strongin, Zachary, Harper, Justin L., Tharp, Gregory K., Pellegrini, Kathryn L., Kirejczyk, Shannon, Zandi, Keivan, Tao, Sijia, Horton, Tristan R., Beagle, Elizabeth N., Mahar, Ernestine A., Lee, Michelle Y.H., Cohen, Joyce, Jean, Sherrie M., Wood, Jennifer S., Connor-Stroud, Fawn, Stammen, Rachelle L., Delmas, Olivia M., Wang, Shelly, Cooney, Kimberly A., Sayegh, Michael N., Wang, Lanfang, Filev, Peter D., Weiskopf, Daniela, Silvestri, Guido, Waggoner, Jesse, Piantadosi, Anne, Kasturi, Sudhir P., Al-Shakhshir, Hilmi, Ribeiro, Susan P., Sekaly, Rafick P., Levit, Rebecca D., Estes, Jacob D., Vanderford, Thomas H., Schinazi, Raymond F., Bosinger, Steven E., Paiardini, Mirko
Publicado 2021