V(D)J Rearrangement Is Dispensable for Producing CDR-H3 Sequence Diversity in a Gene Converting Species

por Leighton, Philip A., Morales, Jacqueline, Harriman, William D., Ching, Kathryn H.
Publicado 2018

Expression of human lambda expands the repertoire of OmniChickens

por Ching, Kathryn H., Berg, Kimberley, Morales, Jacqueline, Pedersen, Darlene, Harriman, William D., Abdiche, Yasmina N., Leighton, Philip A.
Publicado 2020

Harnessing Gene Conversion in Chicken B Cells to Create a Human Antibody Sequence Repertoire

por Schusser, Benjamin, Yi, Henry, Collarini, Ellen J., Izquierdo, Shelley Mettler, Harriman, William D., Etches, Robert J., Leighton, Philip A.
Publicado 2013

Common light chain chickens produce human antibodies of high affinity and broad epitope coverage for the engineering of bispecifics

por Ching, Kathryn H., Berg, Kimberley, Reynolds, Kevin, Pedersen, Darlene, Macias, Alba, Abdiche, Yasmina N., Harriman, William D., Leighton, Philip A.
Publicado 2021

Interspecific Germline Transmission of Cultured Primordial Germ Cells

por van de Lavoir, Marie-Cecile, Collarini, Ellen J., Leighton, Philip A., Fesler, Jeffrey, Lu, Daniel R., Harriman, William D., Thiyagasundaram, T. S., Etches, Robert J.
Publicado 2012

Chickens with humanized immunoglobulin genes generate antibodies with high affinity and broad epitope coverage to conserved targets

por Ching, Kathryn H., Collarini, Ellen J., Abdiche, Yasmina N., Bedinger, Daniel, Pedersen, Darlene, Izquierdo, Shelley, Harriman, Rian, Zhu, Lei, Etches, Robert J., van de Lavoir, Marie-Cecile, Harriman, William D., Leighton, Philip A.
Publicado 2017