Foreign DNA capture during CRISPR–Cas adaptive immunity

por Nuñez, James K., Harrington, Lucas B., Kranzusch, Philip J., Engelman, Alan N., Doudna, Jennifer A.
Publicado 2015

A thermostable Cas9 with increased lifetime in human plasma

por Harrington, Lucas B., Paez-Espino, David, Staahl, Brett T., Chen, Janice S., Ma, Enbo, Kyrpides, Nikos C., Doudna, Jennifer A.
Publicado 2017

New CRISPR-Cas systems from uncultivated microbes

por Burstein, David, Harrington, Lucas B., Strutt, Steven C., Probst, Alexander J., Anantharaman, Karthik, Thomas, Brian C., Doudna, Jennifer A., Banfield, Jillian F.
Publicado 2016

Enhanced proofreading governs CRISPR-Cas9 targeting accuracy

por Chen, Janice S., Dagdas, Yavuz S., Kleinstiver, Benjamin P., Welch, Moira M., Sousa, Alexander A., Harrington, Lucas B., Sternberg, Samuel H., Joung, J. Keith, Yildiz, Ahmet, Doudna, Jennifer A.
Publicado 2017

Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2

por Thavalingam, Annoj, Cheng, Zhi, Garcia, Bianca, Huang, Xue, Shah, Megha, Sun, Wei, Wang, Min, Harrington, Lucas, Hwang, Sungwon, Hidalgo-Reyes, Yurima, Sontheimer, Erik J., Doudna, Jennifer, Davidson, Alan R., Moraes, Trevor F., Wang, Yanli, Maxwell, Karen L.
Publicado 2019

CRISPR-CasX is an RNA-dominated enzyme active for human genome editing

por Liu, Jun-Jie, Orlova, Natalia, Oakes, Benjamin L., Ma, Enbo, Spinner, Hannah B., Baney, Katherine L.M., Chuck, Jonathan, Tan, Dan, Knott, Gavin J., Harrington, Lucas B., Al-Shayeb, Basem, Wagner, Alexander, Brötzmann, Julian, Staahl, Brett T., Talyor, Kian L., Desmarais, John, Nogales, Eva, Doudna, Jennifer A.
Publicado 2019