Concepts of multi-level dynamical modelling: understanding mechanisms of squamous cell carcinoma development in Fanconi anemia

por Velleuer, Eunike, Domínguez-Hüttinger, Elisa, Rodríguez, Alfredo, Harris, Leonard A., Carlberg, Carsten
Publicado 2023

Exact Hybrid Particle/Population Simulation of Rule-Based Models of Biochemical Systems

por Hogg, Justin S., Harris, Leonard A., Stover, Lori J., Nair, Niketh S., Faeder, James R.
Publicado 2014

A drift-diffusion checkpoint model predicts a highly variable and growth-factor-sensitive portion of the cell cycle G1 phase

por Jones, Zack W., Leander, Rachel, Quaranta, Vito, Harris, Leonard A., Tyson, Darren R.
Publicado 2018

Real-time luminescence enables continuous drug–response analysis in adherent and suspension cell lines

por Wandishin, Clayton M., Robbins, Charles John, Tyson, Darren R., Harris, Leonard A., Quaranta, Vito
Publicado 2022

Involvement of Epithelial–Mesenchymal Transition Genes in Small Cell Lung Cancer Phenotypic Plasticity

por Groves, Sarah M., Panchy, Nicholas, Tyson, Darren R., Harris, Leonard A., Quaranta, Vito, Hong, Tian
Publicado 2023

MOSBIE: a tool for comparison and analysis of rule-based biochemical models

por E Wenskovitch, John, Harris, Leonard A, Tapia, Jose-Juan, Faeder, James R, Marai, G Elisabeta
Publicado 2014

Unsupervised logic-based mechanism inference for network-driven biological processes

por Prugger, Martina, Einkemmer, Lukas, Beik, Samantha P., Wasdin, Perry T., Harris, Leonard A., Lopez, Carlos F.
Publicado 2021

Thunor: visualization and analysis of high-throughput dose–response datasets

por Lubbock, Alexander L R, Harris, Leonard A, Quaranta, Vito, Tyson, Darren R, Lopez, Carlos F
Publicado 2021

Unified tumor growth mechanisms from multimodel inference and dataset integration

por Beik, Samantha P., Harris, Leonard A., Kochen, Michael A., Sage, Julien, Quaranta, Vito, Lopez, Carlos F.
Publicado 2023

An in vitro model of tumor heterogeneity resolves genetic, epigenetic, and stochastic sources of cell state variability

por Hayford, Corey E., Tyson, Darren R., Robbins, C. Jack, Frick, Peter L., Quaranta, Vito, Harris, Leonard A.
Publicado 2021

GPU-powered model analysis with PySB/cupSODA

por Harris, Leonard A, Nobile, Marco S, Pino, James C, Lubbock, Alexander L R, Besozzi, Daniela, Mauri, Giancarlo, Cazzaniga, Paolo, Lopez, Carlos F
Publicado 2017

An unbiased metric of antiproliferative drug effect in vitro

por Harris, Leonard A., Frick, Peter L., Garbett, Shawn P., Hardeman, Keisha N., Paudel, B. Bishal, Lopez, Carlos F., Quaranta, Vito, Tyson, Darren R.
Publicado 2016

Activated Oncogenic Pathway Modifies Iron Network in Breast Epithelial Cells: A Dynamic Modeling Perspective

por Chifman, Julia, Arat, Seda, Deng, Zhiyong, Lemler, Erica, Pino, James C., Harris, Leonard A., Kochen, Michael A., Lopez, Carlos F., Akman, Steven A., Torti, Frank M., Torti, Suzy V., Laubenbacher, Reinhard
Publicado 2017

Systems biology markup language (SBML) level 3 package: multistate, multicomponent and multicompartment species, version 1, release 2

por Zhang, Fengkai, Smith, Lucian P., Blinov, Michael L., Faeder, James, Hlavacek, William S., Juan Tapia, Jose, Keating, Sarah M., Rodriguez, Nicolas, Dräger, Andreas, Harris, Leonard A., Finney, Andrew, Hu, Bin, Hucka, Michael, Meier-Schellersheim, Martin
Publicado 2020

Processes in DNA damage response from a whole-cell multi-omics perspective

por Pino, James C., Lubbock, Alexander L.R., Harris, Leonard A., Gutierrez, Danielle B., Farrow, Melissa A., Muszynski, Nicole, Tsui, Tina, Sherrod, Stacy D., Norris, Jeremy L., McLean, John A., Caprioli, Richard M., Wikswo, John P., Lopez, Carlos F.
Publicado 2022