Three Decades of Amyloid Beta Synthesis: Challenges and Advances

por Kasim, Johanes K., Kavianinia, Iman, Harris, Paul W. R., Brimble, Margaret A.
Publicado 2019

An Insight into FDA Approved Antibody-Drug Conjugates for Cancer Therapy

por Tong, Juliana T. W., Harris, Paul W. R., Brimble, Margaret A., Kavianinia, Iman
Publicado 2021

Aminovinyl Cysteine Containing Peptides: A Unique Motif That Imparts Key Biological Activity

por Grant-Mackie, Emily S., Williams, Elyse T., Harris, Paul W. R., Brimble, Margaret A.
Publicado 2021

Structure and Activity of Streptococcus pyogenes SipA: A Signal Peptidase-Like Protein Essential for Pilus Polymerisation

por Young, Paul G., Proft, Thomas, Harris, Paul W. R., Brimble, Margaret A., Baker, Edward N.
Publicado 2014

Peptide Lipidation – A Synthetic Strategy to Afford Peptide Based Therapeutics

por Kowalczyk, Renata, Harris, Paul W. R., Williams, Geoffrey M., Yang, Sung-Hyun, Brimble, Margaret A.
Publicado 2017

Thiol-ene Enabled Chemical Synthesis of Truncated S-Lipidated Teixobactin Analogs

por Yim, Victor V., Cameron, Alan J., Kavianinia, Iman, Harris, Paul W. R., Brimble, Margaret A.
Publicado 2020

Identification of Key Functional Motifs of Native Amelogenin Protein for Dental Enamel Remineralisation

por Dissanayake, Shama S. M., Ekambaram, Manikandan, Li, Kai Chun, Harris, Paul W. R., Brimble, Margaret A.
Publicado 2020

Synthesis and activity of a diselenide bond mimetic of the antimicrobial protein caenopore-5

por Medini, Karima, Harris, Paul. W. R., Menorca, Ayana, Hards, Kiel, Cook, Gregory. M., Brimble, Margaret. A.
Publicado 2016

Synthesis and Systematic Study on the Effect of Different PEG Units on Stability of PEGylated, Integrin-αvβ6-Specific A20FMDV2 Analogues in Rat Serum and Human Plasma

por Hung, Kuo-yuan, Kowalczyk, Renata, Desai, Ami, Brimble, Margaret A., Marshall, John F., Harris, Paul W. R.
Publicado 2022

Flow-Based Fmoc-SPPS Preparation and SAR Study of Cathelicidin-PY Reveals Selective Antimicrobial Activity

por Dissanayake, Shama, He, Junming, Yang, Sung H., Brimble, Margaret A., Harris, Paul W. R., Cameron, Alan J.
Publicado 2023

Peptide binding to a bacterial signal peptidase visualized by peptide tethering and carrier-driven crystallization

por Ting, Yi Tian, Harris, Paul W. R., Batot, Gaelle, Brimble, Margaret A., Baker, Edward N., Young, Paul G.
Publicado 2016

PAC(1), VPAC(1), and VPAC(2) Receptor Expression in Rat and Human Trigeminal Ganglia: Characterization of PACAP-Responsive Receptor Antibodies

por Tasma, Zoe, Siow, Andrew, Harris, Paul W. R., Brimble, Margaret A., O’Carroll, Simon J., Hay, Debbie L., Walker, Christopher S.
Publicado 2022

Synthesis and Biological Evaluation of Termini-Modified and Cyclic Variants of the Connexin43 Inhibitor Peptide5

por Crystal Chan, Sin Hang, Griffin, Jarred M., Clemett, Connor A., Brimble, Margaret A., O’Carroll, Simon J., Harris, Paul W. R.
Publicado 2022

A novel tyrosine hyperoxidation enables selective peptide cleavage

por Zhang, Shengping, De Leon Rodriguez, Luis M., Li, Freda F., Huang, Renjie, Leung, Ivanhoe K. H., Harris, Paul W. R., Brimble, Margaret A.
Publicado 2022

The Anti-Tubercular Aminolipopeptide Trichoderin A Displays Selective Toxicity against Human Pancreatic Ductal Adenocarcinoma Cells Cultured under Glucose Starvation

por Kasim, Johanes K., Hong, Jiwon, Hickey, Anthony J. R., Phillips, Anthony R. J., Windsor, John A., Harris, Paul W. R., Brimble, Margaret A., Kavianinia, Iman
Publicado 2023

Total chemical synthesis of glycocin F and analogues: S-glycosylation confers improved antimicrobial activity

por Amso, Zaid, Bisset, Sean W., Yang, Sung-Hyun, Harris, Paul W. R., Wright, Tom H., Navo, Claudio D., Patchett, Mark L., Norris, Gillian E., Brimble, Margaret A.
Publicado 2018

A Concise Synthetic Strategy Towards the Novel Calcium-dependent Lipopeptide Antibiotic, Malacidin A and Analogues

por Kovalenko, Nadiia, Howard, Georgina K., Swain, Jonathan A., Hermant, Yann, Cameron, Alan J., Cook, Gregory M., Ferguson, Scott A., Stubbing, Louise A., Harris, Paul W. R., Brimble, Margaret A.
Publicado 2021

Genome mining, isolation, chemical synthesis and biological evaluation of a novel lanthipeptide, tikitericin, from the extremophilic microorganism Thermogemmatispora strain T81

por Xu, Buzhe, Aitken, Emma J., Baker, Benjamin P., Turner, Claire A., Harvey, Joanne E., Stott, Matthew B., Power, Jean F., Harris, Paul W. R., Keyzers, Robert A., Brimble, Margaret A.
Publicado 2018

“CLipP”ing on lipids to generate antibacterial lipopeptides

por Yim, Victor, Kavianinia, Iman, Knottenbelt, Melanie K., Ferguson, Scott A., Cook, Gregory M., Swift, Simon, Chakraborty, Aparajita, Allison, Jane R., Cameron, Alan J., Harris, Paul W. R., Brimble, Margaret A.
Publicado 2020

Lipidated Calcitonin Gene-Related Peptide (CGRP) Peptide Antagonists Retain CGRP Receptor Activity and Attenuate CGRP Action In Vivo

por Jamaluddin, Aqfan, Chuang, Chia-Lin, Williams, Elyse T., Siow, Andrew, Yang, Sung Hyun, Harris, Paul W. R., Petersen, Jakeb S. S. M., Bower, Rebekah L., Chand, Shanan, Brimble, Margaret A., Walker, Christopher S., Hay, Debbie L., Loomes, Kerry M.
Publicado 2022