Predicting breast cancer risk using interacting genetic and demographic factors and machine learning

por Behravan, Hamid, Hartikainen, Jaana M., Tengström, Maria, Kosma, Veli–Matti, Mannermaa, Arto
Publicado 2020

High mutation burden of circulating cell‐free DNA in early‐stage breast cancer patients is associated with a poor relapse‐free survival

por Kujala, Jouni, Hartikainen, Jaana M., Tengström, Maria, Sironen, Reijo, Kosma, Veli‐Matti, Mannermaa, Arto
Publicado 2020

The debatable presence of PIWI‐interacting RNAs in invasive breast cancer

por Kärkkäinen, Emmi, Heikkinen, Sami, Tengström, Maria, Kosma, Veli‐Matti, Mannermaa, Arto, Hartikainen, Jaana M.
Publicado 2021

Expression profiles of small non-coding RNAs in breast cancer tumors characterize clinicopathological features and show prognostic and predictive potential

por Kärkkäinen, Emmi, Heikkinen, Sami, Tengström, Maria, Kosma, Veli-Matti, Mannermaa, Arto, Hartikainen, Jaana M.
Publicado 2022

Machine learning identifies interacting genetic variants contributing to breast cancer risk: A case study in Finnish cases and controls

por Behravan, Hamid, Hartikainen, Jaana M., Tengström, Maria, Pylkäs, Katri, Winqvist, Robert, Kosma, Veli–Matti, Mannermaa, Arto
Publicado 2018

Circulating Cell-Free DNA Reflects the Clonal Evolution of Breast Cancer Tumors

por Kujala, Jouni, Hartikainen, Jaana M., Tengström, Maria, Sironen, Reijo, Auvinen, Päivi, Kosma, Veli-Matti, Mannermaa, Arto
Publicado 2022

Type II Transmembrane Serine Protease Gene Variants Associate with Breast Cancer

por Luostari, Kaisa, Hartikainen, Jaana M., Tengström, Maria, Palvimo, Jorma J., Kataja, Vesa, Mannermaa, Arto, Kosma, Veli-Matti
Publicado 2014

MCF10CA Breast Cancer Cells Utilize Hyaluronan-Coated EV-Rich Trails for Coordinated Migration

por Aaltonen, Niina, Kyykallio, Heikki, Tollis, Sylvain, Capra, Janne, Hartikainen, Jaana M., Matilainen, Johanna, Oikari, Sanna, Rilla, Kirsi
Publicado 2022

Chromatin-directed proteomics-identified network of endogenous androgen receptor in prostate cancer cells

por Launonen, Kaisa-Mari, Paakinaho, Ville, Sigismondo, Gianluca, Malinen, Marjo, Sironen, Reijo, Hartikainen, Jaana M., Laakso, Hanna, Visakorpi, Tapio, Krijgsveld, Jeroen, Niskanen, Einari A., Palvimo, Jorma J.
Publicado 2021

CD44s Assembles Hyaluronan Coat on Filopodia and Extracellular Vesicles and Induces Tumorigenicity of MKN74 Gastric Carcinoma Cells

por Härkönen, Kai, Oikari, Sanna, Kyykallio, Heikki, Capra, Janne, Hakkola, Sini, Ketola, Kirsi, Thanigai Arasu, Uma, Daaboul, George, Malloy, Andrew, Oliveira, Carla, Jokelainen, Otto, Sironen, Reijo, Hartikainen, Jaana M., Rilla, Kirsi
Publicado 2019

Case-control analysis of truncating mutations in DNA damage response genes connects TEX15 and FANCD2 with hereditary breast cancer susceptibility

por Mantere, Tuomo, Tervasmäki, Anna, Nurmi, Anna, Rapakko, Katrin, Kauppila, Saila, Tang, Jiangbo, Schleutker, Johanna, Kallioniemi, Anne, Hartikainen, Jaana M., Mannermaa, Arto, Nieminen, Pentti, Hanhisalo, Riitta, Lehto, Sini, Suvanto, Maija, Grip, Mervi, Jukkola-Vuorinen, Arja, Tengström, Maria, Auvinen, Päivi, Kvist, Anders, Borg, Åke, Blomqvist, Carl, Aittomäki, Kristiina, Greenberg, Roger A., Winqvist, Robert, Nevanlinna, Heli, Pylkäs, Katri
Publicado 2017

The UGT1A6_19_GG genotype is a breast cancer risk factor

por Justenhoven, Christina, Obazee, Ofure, Winter, Stefan, Rabstein, Sylvia, Lotz, Anne, Harth, Volker, Pesch, Beate, Brüning, Thomas, Baisch, Christian, Hartikainen, Jaana M., Mannermaa, Arto, Kosma, Veli-Matti, Kataja, Vesa, Winqvist, Robert, Pylkäs, Katri, Jukkola-Vuorinen, Arja, Grip, Mervi, Fasching, Peter A., Beckmann, Matthias, Ekici, Arif B., Hein, Alexander, Hall, Per, Li, Jingmei, Chang-Claude, Jenny, Flesch-Janys, Dieter, Seibold, Petra, Rudolph, Anja, Hamann, Ute, Ko, Yon-Dschun, Brauch, Hiltrud
Publicado 2013

A polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients

por Seibold, Petra, Schmezer, Peter, Behrens, Sabine, Michailidou, Kyriaki, Bolla, Manjeet K., Wang, Qin, Flesch-Janys, Dieter, Nevanlinna, Heli, Fagerholm, Rainer, Aittomäki, Kristiina, Blomqvist, Carl, Margolin, Sara, Mannermaa, Arto, Kataja, Vesa, Kosma, Veli-Matti, Hartikainen, Jaana M., Lambrechts, Diether, Wildiers, Hans, Kristensen, Vessela, Alnæs, Grethe Grenaker, Nord, Silje, Borresen-Dale, Anne-Lise, Hooning, Maartje J., Hollestelle, Antoinette, Jager, Agnes, Seynaeve, Caroline, Li, Jingmei, Liu, Jianjun, Humphreys, Keith, Dunning, Alison M., Rhenius, Valerie, Shah, Mitul, Kabisch, Maria, Torres, Diana, Ulmer, Hans-Ulrich, Hamann, Ute, Schildkraut, Joellen M., Purrington, Kristen S., Couch, Fergus J., Hall, Per, Pharoah, Paul, Easton, Doug F., Schmidt, Marjanka K., Chang-Claude, Jenny, Popanda, Odilia
Publicado 2015

Annexin A1 expression in a pooled breast cancer series: association with tumor subtypes and prognosis

por Sobral-Leite, Marcelo, Wesseling, Jelle, Smit, Vincent T. H. B. M., Nevanlinna, Heli, van Miltenburg, Martine H., Sanders, Joyce, Hofland, Ingrid, Blows, Fiona M., Coulson, Penny, Patrycja, Gazinska, Schellens, Jan H. M., Fagerholm, Rainer, Heikkilä, Päivi, Aittomäki, Kristiina, Blomqvist, Carl, Provenzano, Elena, Ali, Hamid Raza, Figueroa, Jonine, Sherman, Mark, Lissowska, Jolanta, Mannermaa, Arto, Kataja, Vesa, Kosma, Veli-Matti, Hartikainen, Jaana M., Phillips, Kelly-Anne, Couch, Fergus J., Olson, Janet E., Vachon, Celine, Visscher, Daniel, Brenner, Hermann, Butterbach, Katja, Arndt, Volker, Holleczek, Bernd, Hooning, Maartje J., Hollestelle, Antoinette, Martens, John W. M., van Deurzen, Carolien H. M., van de Water, Bob, Broeks, Annegien, Chang-Claude, Jenny, Chenevix-Trench, Georgia, Easton, Douglas F., Pharoah, Paul D. P., García-Closas, Montserrat, de Graauw, Marjo, Schmidt, Marjanka K.
Publicado 2015

E-cadherin breast tumor expression, risk factors and survival: Pooled analysis of 5,933 cases from 12 studies in the Breast Cancer Association Consortium

por Horne, Hisani N., Oh, Hannah, Sherman, Mark E., Palakal, Maya, Hewitt, Stephen M., Schmidt, Marjanka K., Milne, Roger L., Hardisson, David, Benitez, Javier, Blomqvist, Carl, Bolla, Manjeet K., Brenner, Hermann, Chang-Claude, Jenny, Cora, Renata, Couch, Fergus J., Cuk, Katarina, Devilee, Peter, Easton, Douglas F., Eccles, Diana M., Eilber, Ursula, Hartikainen, Jaana M., Heikkilä, Päivi, Holleczek, Bernd, Hooning, Maartje J., Jones, Michael, Keeman, Renske, Mannermaa, Arto, Martens, John W. M., Muranen, Taru A., Nevanlinna, Heli, Olson, Janet E., Orr, Nick, Perez, Jose I. A., Pharoah, Paul D. P., Ruddy, Kathryn J., Saum, Kai-Uwe, Schoemaker, Minouk J., Seynaeve, Caroline, Sironen, Reijo, Smit, Vincent T. H. B. M., Swerdlow, Anthony J., Tengström, Maria, Thomas, Abigail S., Timmermans, A. Mieke, Tollenaar, Rob A. E. M., Troester, Melissa A., van Asperen, Christi J., van Deurzen, Carolien H. M., Van Leeuwen, Flora F., Van’t Veer, Laura J., García-Closas, Montserrat, Figueroa, Jonine D.
Publicado 2018

Genetic variation in the immunosuppression pathway genes and breast cancer susceptibility: a pooled analysis of 42,510 cases and 40,577 controls from the Breast Cancer Association...

por Lei, Jieping, Rudolph, Anja, Moysich, Kirsten B., Behrens, Sabine, Goode, Ellen L., Bolla, Manjeet K., Dennis, Joe, Dunning, Alison M., Easton, Douglas F., Wang, Qin, Benitez, Javier, Hopper, John L., Southey, Melissa C., Schmidt, Marjanka K., Broeks, Annegien, Fasching, Peter A., Haeberle, Lothar, Peto, Julian, dos-Santos-Silva, Isabel, Sawyer, Elinor J., Tomlinson, Ian, Burwinkel, Barbara, Marmé, Frederik, Guénel, Pascal, Truong, Thérèse, Bojesen, Stig E., Flyger, Henrik, Nielsen, Sune F., Nordestgaard, Børge G., González-Neira, Anna, Menéndez, Primitiva, Anton-Culver, Hoda, Neuhausen, Susan L., Brenner, Hermann, Arndt, Volker, Meindl, Alfons, Schmutzler, Rita K., Brauch, Hiltrud, Hamann, Ute, Nevanlinna, Heli, Fagerholm, Rainer, Dörk, Thilo, Bogdanova, Natalia V., Mannermaa, Arto, Hartikainen, Jaana M., Van Dijck, Laurien, Smeets, Ann, Flesch-Janys, Dieter, Eilber, Ursula, Radice, Paolo, Peterlongo, Paolo, Couch, Fergus J., Hallberg, Emily, Giles, Graham G., Milne, Roger L., Haiman, Christopher A., Schumacher, Fredrick, Simard, Jacques, Goldberg, Mark S., Kristensen, Vessela, Borresen-Dale, Anne-Lise, Zheng, Wei, Beeghly-Fadiel, Alicia, Winqvist, Robert, Grip, Mervi, Andrulis, Irene L., Glendon, Gord, García-Closas, Montserrat, Figueroa, Jonine, Czene, Kamila, Brand, Judith S., Darabi, Hatef, Eriksson, Mikael, Hall, Per, Li, Jingmei, Cox, Angela, Cross, Simon S., Pharoah, Paul D. P., Shah, Mitul, Kabisch, Maria, Torres, Diana, Jakubowska, Anna, Lubinski, Jan, Ademuyiwa, Foluso, Ambrosone, Christine B., Swerdlow, Anthony, Jones, Michael, Chang-Claude, Jenny
Publicado 2015

Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy

por Lei, Jieping, Rudolph, Anja, Moysich, Kirsten B, Rafiq, Sajjad, Behrens, Sabine, Goode, Ellen L, Pharoah, Paul PD, Seibold, Petra, Fasching, Peter A, Andrulis, Irene L, Kristensen, Vessela N, Couch, Fergus J, Hamann, Ute, Hooning, Maartje J, Nevanlinna, Heli, Eilber, Ursula, Bolla, Manjeet K, Dennis, Joe, Wang, Qin, Lindblom, Annika, Mannermaa, Arto, Lambrechts, Diether, García-Closas, Montserrat, Hall, Per, Chenevix-Trench, Georgia, Shah, Mitul, Luben, Robert, Haeberle, Lothar, Ekici, Arif B, Beckmann, Matthias W, Knight, Julia A, Glendon, Gord, Tchatchou, Sandrine, Alnæs, Grethe I Grenaker, Borresen-Dale, Anne-Lise, Nord, Silje, Olson, Janet E, Hallberg, Emily, Vachon, Celine, Torres, Diana, Ulmer, Hans-Ulrich, Rüdiger, Thomas, Jager, Agnes, van Deurzen, Carolien HM, Tilanus-Linthorst, Madeleine MA, Muranen, Taru A, Aittomäki, Kristiina, Blomqvist, Carl, Margolin, Sara, Kosma, Veli-Matti, Hartikainen, Jaana M, Kataja, Vesa, Hatse, Sigrid, Wildiers, Hans, Smeets, Ann, Figueroa, Jonine, Chanock, Stephen J, Lissowska, Jolanta, Li, Jingmei, Humphreys, Keith, Phillips, Kelly-Anne, Linn, Sabine, Cornelissen, Sten, van den Broek, Sandra Alexandra J, Kang, Daehee, Choi, Ji-Yeob, Park, Sue K, Yoo, Keun-Young, Hsiung, Chia-Ni, Wu, Pei-Ei, Hou, Ming-Feng, Shen, Chen-Yang, Teo, Soo Hwang, Taib, Nur Aishah Mohd, Yip, Cheng Har, Ho, Gwo Fuang, Matsuo, Keitaro, Ito, Hidemi, Iwata, Hiroji, Tajima, Kazuo, Dunning, Alison M, Benitez, Javier, Czene, Kamila, Sucheston, Lara E, Maishman, Tom, Tapper, William J, Eccles, Diana, Easton, Douglas F, Schmidt, Marjanka K, Chang-Claude, Jenny
Publicado 2015

Pathology of Tumors Associated With Pathogenic Germline Variants in 9 Breast Cancer Susceptibility Genes

por Mavaddat, Nasim, Dorling, Leila, Carvalho, Sara, Allen, Jamie, González-Neira, Anna, Keeman, Renske, Bolla, Manjeet K., Dennis, Joe, Wang, Qin, Ahearn, Thomas U., Andrulis, Irene L., Beckmann, Matthias W., Behrens, Sabine, Benitez, Javier, Bermisheva, Marina, Blomqvist, Carl, Bogdanova, Natalia V., Bojesen, Stig E., Briceno, Ignacio, Brüning, Thomas, Camp, Nicola J., Campbell, Archie, Castelao, Jose E., Chang-Claude, Jenny, Chanock, Stephen J., Chenevix-Trench, Georgia, Christiansen, Hans, Czene, Kamila, Dörk, Thilo, Eriksson, Mikael, Evans, D. Gareth, Fasching, Peter A., Figueroa, Jonine D., Flyger, Henrik, Gabrielson, Marike, Gago-Dominguez, Manuela, Geisler, Jürgen, Giles, Graham G., Guénel, Pascal, Hadjisavvas, Andreas, Hahnen, Eric, Hall, Per, Hamann, Ute, Hartikainen, Jaana M., Hartman, Mikael, Hoppe, Reiner, Howell, Anthony, Jakubowska, Anna, Jung, Audrey, Khusnutdinova, Elza K., Kristensen, Vessela N., Li, Jingmei, Lim, Swee Ho, Lindblom, Annika, Loizidou, Maria A., Lophatananon, Artitaya, Lubiński, Jan, Madsen, Michael J., Mannermaa, Arto, Manoochehri, Mehdi, Margolin, Sara, Mavroudis, Dimitrios, Milne, Roger L., Mohd Taib, Nur Aishah, Morra, Anna, Muir, Kenneth, Obi, Nadia, Osorio, Ana, Park-Simon, Tjoung-Won, Peterlongo, Paolo, Radice, Paolo, Saloustros, Emmanouil, Sawyer, Elinor J., Schmutzler, Rita K., Shah, Mitul, Sim, Xueling, Southey, Melissa C., Thorne, Heather, Tomlinson, Ian, Torres, Diana, Truong, Thérèse, Yip, Cheng Har, Spurdle, Amanda B., Vreeswijk, Maaike P.G., Dunning, Alison M., García-Closas, Montserrat, Pharoah, Paul D.P., Kvist, Anders, Muranen, Taru A., Nevanlinna, Heli, Teo, Soo Hwang, Devilee, Peter, Schmidt, Marjanka K., Easton, Douglas F.
Publicado 2022

Evidence of Gene–Environment Interactions between Common Breast Cancer Susceptibility Loci and Established Environmental Risk Factors

por Nickels, Stefan, Truong, Thérèse, Hein, Rebecca, Stevens, Kristen, Buck, Katharina, Behrens, Sabine, Eilber, Ursula, Schmidt, Martina, Häberle, Lothar, Vrieling, Alina, Gaudet, Mia, Figueroa, Jonine, Schoof, Nils, Spurdle, Amanda B., Rudolph, Anja, Fasching, Peter A., Hopper, John L., Makalic, Enes, Schmidt, Daniel F., Southey, Melissa C., Beckmann, Matthias W., Ekici, Arif B., Fletcher, Olivia, Gibson, Lorna, dos Santos Silva, Isabel, Peto, Julian, Humphreys, Manjeet K., Wang, Jean, Cordina-Duverger, Emilie, Menegaux, Florence, Nordestgaard, Børge G., Bojesen, Stig E., Lanng, Charlotte, Anton-Culver, Hoda, Ziogas, Argyrios, Bernstein, Leslie, Clarke, Christina A., Brenner, Hermann, Müller, Heiko, Arndt, Volker, Stegmaier, Christa, Brauch, Hiltrud, Brüning, Thomas, Harth, Volker, The GENICA Network, Mannermaa, Arto, Kataja, Vesa, Kosma, Veli-Matti, Hartikainen, Jaana M., kConFab, Group, AOCS Management, Lambrechts, Diether, Smeets, Dominiek, Neven, Patrick, Paridaens, Robert, Flesch-Janys, Dieter, Obi, Nadia, Wang-Gohrke, Shan, Couch, Fergus J., Olson, Janet E., Vachon, Celine M., Giles, Graham G., Severi, Gianluca, Baglietto, Laura, Offit, Kenneth, John, Esther M., Miron, Alexander, Andrulis, Irene L., Knight, Julia A., Glendon, Gord, Mulligan, Anna Marie, Chanock, Stephen J., Lissowska, Jolanta, Liu, Jianjun, Cox, Angela, Cramp, Helen, Connley, Dan, Balasubramanian, Sabapathy, Dunning, Alison M., Shah, Mitul, Trentham-Dietz, Amy, Newcomb, Polly, Titus, Linda, Egan, Kathleen, Cahoon, Elizabeth K., Rajaraman, Preetha, Sigurdson, Alice J., Doody, Michele M., Guénel, Pascal, Pharoah, Paul D. P., Schmidt, Marjanka K., Hall, Per, Easton, Doug F., Garcia-Closas, Montserrat, Milne, Roger L., Chang-Claude, Jenny
Publicado 2013

RAD51B in Familial Breast Cancer

por Pelttari, Liisa M., Khan, Sofia, Vuorela, Mikko, Kiiski, Johanna I., Vilske, Sara, Nevanlinna, Viivi, Ranta, Salla, Schleutker, Johanna, Winqvist, Robert, Kallioniemi, Anne, Dörk, Thilo, Bogdanova, Natalia V., Figueroa, Jonine, Pharoah, Paul D. P., Schmidt, Marjanka K., Dunning, Alison M., García-Closas, Montserrat, Bolla, Manjeet K., Dennis, Joe, Michailidou, Kyriaki, Wang, Qin, Hopper, John L., Southey, Melissa C., Rosenberg, Efraim H., Fasching, Peter A., Beckmann, Matthias W., Peto, Julian, dos-Santos-Silva, Isabel, Sawyer, Elinor J., Tomlinson, Ian, Burwinkel, Barbara, Surowy, Harald, Guénel, Pascal, Truong, Thérèse, Bojesen, Stig E., Nordestgaard, Børge G., Benitez, Javier, González-Neira, Anna, Neuhausen, Susan L., Anton-Culver, Hoda, Brenner, Hermann, Arndt, Volker, Meindl, Alfons, Schmutzler, Rita K., Brauch, Hiltrud, Brüning, Thomas, Lindblom, Annika, Margolin, Sara, Mannermaa, Arto, Hartikainen, Jaana M., Chenevix-Trench, Georgia, Van Dyck, Laurien, Janssen, Hilde, Chang-Claude, Jenny, Rudolph, Anja, Radice, Paolo, Peterlongo, Paolo, Hallberg, Emily, Olson, Janet E., Giles, Graham G., Milne, Roger L., Haiman, Christopher A., Schumacher, Fredrick, Simard, Jacques, Dumont, Martine, Kristensen, Vessela, Borresen-Dale, Anne-Lise, Zheng, Wei, Beeghly-Fadiel, Alicia, Grip, Mervi, Andrulis, Irene L., Glendon, Gord, Devilee, Peter, Seynaeve, Caroline, Hooning, Maartje J., Collée, Margriet, Cox, Angela, Cross, Simon S., Shah, Mitul, Luben, Robert N., Hamann, Ute, Torres, Diana, Jakubowska, Anna, Lubinski, Jan, Couch, Fergus J., Yannoukakos, Drakoulis, Orr, Nick, Swerdlow, Anthony, Darabi, Hatef, Li, Jingmei, Czene, Kamila, Hall, Per, Easton, Douglas F., Mattson, Johanna, Blomqvist, Carl, Aittomäki, Kristiina, Nevanlinna, Heli
Publicado 2016