An Improved Synthesis of N-(4-[(18)F]Fluorobenzoyl)-Interleukin-2 for the Preclinical PET Imaging of Tumour-Infiltrating T-cells in CT26 and MC38 Colon Cancer Models

por Khanapur, Shivashankar, Yong, Fui Fong, Hartimath, Siddesh V., Jiang, Lingfan, Ramasamy, Boominathan, Cheng, Peter, Narayanaswamy, Pradeep, Goggi, Julian L., Robins, Edward George
Publicado 2021

Therapeutic potential of nimotuzumab PEGylated-maytansine antibody drug conjugates against EGFR positive xenograft

por Hartimath, Siddesh V., El-Sayed, Ayman, Makhlouf, Amal, Bernhard, Wendy, Gonzalez, Carolina, Hill, Wayne, Parada, Angel Casaco, Barreto, Kris, Geyer, Clarence Ronald, Fonge, Humphrey
Publicado 2019

Development and preclinical evaluation of cixutumumab drug conjugates in a model of insulin growth factor receptor I (IGF-1R) positive cancer

por Solomon, Viswas Raja, Alizadeh, Elahe, Bernhard, Wendy, Makhlouf, Amal, Hartimath, Siddesh V., Hill, Wayne, El-Sayed, Ayman, Barreto, Kris, Geyer, Clarence Ronald, Fonge, Humphrey
Publicado 2020

Granzyme B PET Imaging in Response to In Situ Vaccine Therapy Combined with αPD1 in a Murine Colon Cancer Model

por Hartimath, Siddesh V., Ramasamy, Boominathan, Xuan, Tan Yun, Rong, Tang Jun, Khanapur, Shivashankar, Cheng, Peter, Hwang, You Yi, Robins, Edward G., Goggi, Julian L.
Publicado 2022

Imaging Effector Memory T-Cells Predicts Response to PD1-Chemotherapy Combinations in Colon Cancer

por Goggi, Julian L., Khanapur, Shivashankar, Hartimath, Siddesh V., Ramasamy, Boominathan, Cheng, Peter, Chin, Hui-Xian, Tang, Jun-Rong, Hwang, You-Yi, Robins, Edward G.
Publicado 2022

Imaging Memory T-Cells Stratifies Response to Adjuvant Metformin Combined with αPD-1 Therapy

por Goggi, Julian L., Hartimath, Siddesh V., Khanapur, Shivashankar, Ramasamy, Boominathan, Chin, Zan Feng, Cheng, Peter, Chin, Hui Xian, Hwang, You Yi, Robins, Edward G.
Publicado 2022

Pharmacokinetic properties of radiolabeled mutant Interleukin-2v: a PET imaging study

por Hartimath, Siddesh V., Manuelli, Valeria, Zijlma, Rolf, Signore, Alberto, Nayak, Tapan K., Freimoser-Grundschober, Anne, Klein, Christian, Dierckx, Rudi A.J.O., de Vries, Erik F.J.
Publicado 2018

Granzyme B PET Imaging Stratifies Immune Checkpoint Inhibitor Response in Hepatocellular Carcinoma

por Goggi, Julian L., Ramasamy, Boominathan, Tan, Yun Xuan, Hartimath, Siddesh V., Tang, Jun Rong, Cheng, Peter, Msallam, Rasha, Chacko, Ann-Marie, Hwang, You Yi, Robins, Edward G.
Publicado 2021

Lung endothelial cell antigen cross-presentation to CD8(+)T cells drives malaria-associated lung injury

por Claser, Carla, Nguee, Samantha Yee Teng, Balachander, Akhila, Wu Howland, Shanshan, Becht, Etienne, Gunasegaran, Bavani, Hartimath, Siddesh V., Lee, Audrey W. Q., Theng Theng Ho, Jacqueline, Bing Ong, Chee, Newell, Evan W., Goggi, Julian, Guan Ng, Lai, Renia, Laurent
Publicado 2019

Author Correction: Lung endothelial cell antigen cross-presentation to CD8(+)T cells drives malaria-associated lung injury

por Claser, Carla, Nguee, Samantha Yee Teng, Balachander, Akhila, Howland, Shanshan Wu, Becht, Etienne, Gunasegaran, Bavani, Hartimath, Siddesh V., Lee, Audrey W. Q., Ho, Jacqueline Theng Theng, Ong, Chee Bing, Newell, Evan W., Goggi, Julian, Ng, Lai Guan, Renia, Laurent
Publicado 2019

Imaging Kv1.3 Expressing Memory T Cells as a Marker of Immunotherapy Response

por Goggi, Julian L., Khanapur, Shivashankar, Ramasamy, Boominathan, Hartimath, Siddesh V., Rong, Tang Jun, Cheng, Peter, Tan, Yun Xuan, Yeo, Xin Yi, Jung, Sangyong, Goay, Stephanie Shee Min, Ong, Seow Theng, Hwang, You Yi, Chandy, K. George, Robins, Edward G.
Publicado 2022

Longitudinal [18F]FB-IL-2 PET Imaging to Assess the Immunopathogenicity of O'nyong-nyong Virus Infection

por Chan, Yi-Hao, Teo, Teck-Hui, Torres-Ruesta, Anthony, Hartimath, Siddesh V., Chee, Rhonda Sin-Ling, Khanapur, Shivashankar, Yong, Fui Fong, Ramasamy, Boominathan, Cheng, Peter, Rajarethinam, Ravisankar, Robins, Edward G., Goggi, Julian L., Lum, Fok-Moon, Carissimo, Guillaume, Rénia, Laurent, Ng, Lisa F. P.
Publicado 2020

Granzyme B PET Imaging of Combined Chemotherapy and Immune Checkpoint Inhibitor Therapy in Colon Cancer

por Goggi, Julian L, Hartimath, Siddesh V, Xuan, Tan Yun, Khanapur, Shivashankar, Jieu, Beverly, Chin, Hui Xian, Ramasamy, Boominathan, Cheng, Peter, Rong, Tang Jun, Fong, Yong Fui, Yuen, Tsz Ying, Msallam, Rasha, Chacko, Ann-Marie, Renia, Laurent, Johannes, Charles, Hwang, You Yi, Robins, Edward G
Publicado 2021

Dopamine transporter neuroimaging accurately assesses the maturation of dopamine neurons in a preclinical model of Parkinson’s disease

por Goggi, Julian L., Qiu, Lifeng, Liao, Mei Chih, Khanapur, Shivashankar, Jiang, Lingfan, Boominathan, Ramasamy, Hartimath, Siddesh V., Cheng, Peter, Yong, Fui Fong, Soh, Vanessa, Deng, Xiaozhou, Lin, Youshan Melissa, Haslop, Anna, Tan, Peng Wen, Zeng, Xiaoxia, Lee, Jolene W. L., Zhang, Zhiwei, Sadasivam, Pragalath, Tan, Eng King, Luthra, Sajinder K., Shingleton, William D., Oh, Steve K. W., Zeng, Li, Robins, Edward G.
Publicado 2020

Haploinsufficiency of CYP8B1 associates with increased insulin sensitivity in humans

por Zhong, Shiqi, Chèvre, Raphael, Castaño Mayan, David, Corlianò, Maria, Cochran, Blake J., Sem, Kai Ping, van Dijk, Theo H., Peng, Jianhe, Tan, Liang Juin, Hartimath, Siddesh V., Ramasamy, Boominathan, Cheng, Peter, Groen, Albert K., Kuipers, Folkert, Goggi, Julian L., Drum, Chester, van Dam, Rob M., Tan, Ru San, Rye, Kerry-Anne, Hayden, Michael R., Cheng, Ching-Yu, Chacko, Shaji, Flannick, Jason, Sim, Xueling, Tan, Hong Chang, Singaraja, Roshni R.
Publicado 2022